Podcast
Questions and Answers
What is one key difference between the nervous system and the endocrine system?
What is one key difference between the nervous system and the endocrine system?
Which function is NOT performed by the nervous system?
Which function is NOT performed by the nervous system?
The central nervous system (CNS) is primarily responsible for which of the following?
The central nervous system (CNS) is primarily responsible for which of the following?
How does the nervous system respond to stimuli?
How does the nervous system respond to stimuli?
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What are the two major divisions of the nervous system?
What are the two major divisions of the nervous system?
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Which of the following activities does the nervous system NOT perform?
Which of the following activities does the nervous system NOT perform?
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Which statement is true about the nervous system?
Which statement is true about the nervous system?
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Which aspect of the nervous system's function enhances its ability to maintain homeostasis?
Which aspect of the nervous system's function enhances its ability to maintain homeostasis?
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What is the initial change in membrane potential that leads to the generation of an action potential?
What is the initial change in membrane potential that leads to the generation of an action potential?
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During what phase of an action potential can the membrane not respond to further stimulation?
During what phase of an action potential can the membrane not respond to further stimulation?
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What occurs when voltage-gated sodium channels open during an action potential?
What occurs when voltage-gated sodium channels open during an action potential?
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What happens to the membrane potential at the peak of an action potential?
What happens to the membrane potential at the peak of an action potential?
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Which of the following correctly describes the role of potassium channels during an action potential?
Which of the following correctly describes the role of potassium channels during an action potential?
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What triggers the closing of sodium channels during the action potential?
What triggers the closing of sodium channels during the action potential?
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What is the primary function of microglia in the central nervous system?
What is the primary function of microglia in the central nervous system?
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What type of conduction occurs in unmyelinated axons during action potential propagation?
What type of conduction occurs in unmyelinated axons during action potential propagation?
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Which cells are responsible for forming the myelin sheath around axons in the central nervous system?
Which cells are responsible for forming the myelin sheath around axons in the central nervous system?
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Which neurotoxin is known to prevent sodium ion movement in neurons?
Which neurotoxin is known to prevent sodium ion movement in neurons?
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What distinguishes white matter from gray matter in the central nervous system?
What distinguishes white matter from gray matter in the central nervous system?
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Which potential represents the membrane state just before reaching the threshold for action potential generation?
Which potential represents the membrane state just before reaching the threshold for action potential generation?
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How do Schwann cells function differently from oligodendrocytes in the peripheral nervous system?
How do Schwann cells function differently from oligodendrocytes in the peripheral nervous system?
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What is the final step in the generation of an action potential?
What is the final step in the generation of an action potential?
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Which type of cell lines the cavities in the central nervous system and assists with the circulation of cerebrospinal fluid?
Which type of cell lines the cavities in the central nervous system and assists with the circulation of cerebrospinal fluid?
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What are the small gaps between adjacent cell processes of oligodendrocytes called?
What are the small gaps between adjacent cell processes of oligodendrocytes called?
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Which cells in the peripheral nervous system surround and support neuron cell bodies?
Which cells in the peripheral nervous system surround and support neuron cell bodies?
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Which condition is characterized by the progressive destruction of myelin sheaths in the nervous system?
Which condition is characterized by the progressive destruction of myelin sheaths in the nervous system?
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What is the main function of oligodendrocytes in the nervous system?
What is the main function of oligodendrocytes in the nervous system?
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Which structure contains the cell bodies of neurons in the peripheral nervous system?
Which structure contains the cell bodies of neurons in the peripheral nervous system?
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What type of matter is primarily composed of myelinated axons in the central nervous system?
What type of matter is primarily composed of myelinated axons in the central nervous system?
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What is the primary function of astrocytes in the central nervous system?
What is the primary function of astrocytes in the central nervous system?
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Which neuroglial cell is responsible for creating the blood-brain barrier?
Which neuroglial cell is responsible for creating the blood-brain barrier?
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What is the role of the nodes of Ranvier in myelinated axons?
What is the role of the nodes of Ranvier in myelinated axons?
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What are the two main components of the central nervous system (CNS)?
What are the two main components of the central nervous system (CNS)?
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Which division of the peripheral nervous system (PNS) is responsible for carrying sensory information to the CNS?
Which division of the peripheral nervous system (PNS) is responsible for carrying sensory information to the CNS?
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What is a reflex?
What is a reflex?
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Which systems are included in the autonomic nervous system (ANS)?
Which systems are included in the autonomic nervous system (ANS)?
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What is the primary function of the somatic nervous system (SNS)?
What is the primary function of the somatic nervous system (SNS)?
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How do neuroglia differ from neurons in the nervous system?
How do neuroglia differ from neurons in the nervous system?
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What role do receptors play in the nervous system?
What role do receptors play in the nervous system?
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What is the primary output of a neuron?
What is the primary output of a neuron?
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What is the color of gray matter primarily attributed to?
What is the color of gray matter primarily attributed to?
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What initiates the generation of an action potential in a neuron?
What initiates the generation of an action potential in a neuron?
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Which part of the neuron is responsible for carrying outgoing signals?
Which part of the neuron is responsible for carrying outgoing signals?
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What effect would damage to the afferent division of the PNS likely have?
What effect would damage to the afferent division of the PNS likely have?
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In which type of muscle does the autonomic nervous system primarily operate?
In which type of muscle does the autonomic nervous system primarily operate?
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What is the role of effector organs in the nervous system?
What is the role of effector organs in the nervous system?
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Which of the following are common signs and symptoms of multiple sclerosis (MS)?
Which of the following are common signs and symptoms of multiple sclerosis (MS)?
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What is the typical resting membrane potential of a neuron?
What is the typical resting membrane potential of a neuron?
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Which type of ions is found in high concentrations in the extracellular fluid?
Which type of ions is found in high concentrations in the extracellular fluid?
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What is the role of the sodium-potassium exchange pump in neurons?
What is the role of the sodium-potassium exchange pump in neurons?
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What occurs to the membrane potential during an action potential?
What occurs to the membrane potential during an action potential?
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Which neuroglia would likely increase in number during a CNS infection?
Which neuroglia would likely increase in number during a CNS infection?
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What is a characteristic feature of a polarized plasma membrane?
What is a characteristic feature of a polarized plasma membrane?
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What happens to the permeability of the cell membrane during depolarization?
What happens to the permeability of the cell membrane during depolarization?
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How does the selective permeability of the plasma membrane affect ion movement?
How does the selective permeability of the plasma membrane affect ion movement?
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What contributes to the potential difference across the plasma membrane?
What contributes to the potential difference across the plasma membrane?
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What primarily maintains the negative charge inside a resting neuron?
What primarily maintains the negative charge inside a resting neuron?
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In which part of the nervous system are unipolar neurons primarily found?
In which part of the nervous system are unipolar neurons primarily found?
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What causes the resting potential to be stable over time?
What causes the resting potential to be stable over time?
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What is the primary consequence of a disturbed resting membrane potential?
What is the primary consequence of a disturbed resting membrane potential?
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What happens to the membrane potential during depolarization?
What happens to the membrane potential during depolarization?
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What is the effect of opening gated potassium channels in a cell membrane?
What is the effect of opening gated potassium channels in a cell membrane?
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What distinguishes graded potentials from action potentials?
What distinguishes graded potentials from action potentials?
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How does pressure relate to the generation of an action potential?
How does pressure relate to the generation of an action potential?
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Which statement correctly describes the all-or-none principle?
Which statement correctly describes the all-or-none principle?
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Where does an action potential typically begin in a neuron?
Where does an action potential typically begin in a neuron?
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What is primarily responsible for the propagation of an action potential?
What is primarily responsible for the propagation of an action potential?
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What role do leak channels play in relation to graded potentials?
What role do leak channels play in relation to graded potentials?
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What initiates muscle contraction in skeletal muscle fibers?
What initiates muscle contraction in skeletal muscle fibers?
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What type of ion channels open in response to a depolarization reaching threshold?
What type of ion channels open in response to a depolarization reaching threshold?
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How do graded potentials affect large excitable cells like neurons?
How do graded potentials affect large excitable cells like neurons?
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What is the primary function of the initial segment of the axon membrane?
What is the primary function of the initial segment of the axon membrane?
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Which characteristic is unique to excitable membranes?
Which characteristic is unique to excitable membranes?
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What is the effect of a chemical stimulus that opens gated sodium channels?
What is the effect of a chemical stimulus that opens gated sodium channels?
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What is the primary function of axon terminals?
What is the primary function of axon terminals?
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Which type of neuron has a continuous dendrite and axon with its cell body positioned to one side?
Which type of neuron has a continuous dendrite and axon with its cell body positioned to one side?
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Which neurons make up the efferent division of the PNS that carries instructions from the CNS to effectors?
Which neurons make up the efferent division of the PNS that carries instructions from the CNS to effectors?
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What role do astrocytes play in the nervous system?
What role do astrocytes play in the nervous system?
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Where are interneurons primarily found?
Where are interneurons primarily found?
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What type of receptor monitors the activities of internal organs?
What type of receptor monitors the activities of internal organs?
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Which of the following is a characteristic of multipolar neurons?
Which of the following is a characteristic of multipolar neurons?
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What is a major limitation of typical CNS neurons?
What is a major limitation of typical CNS neurons?
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What is the role of sensory neurons in the nervous system?
What is the role of sensory neurons in the nervous system?
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Which of the following best describes bipolar neurons?
Which of the following best describes bipolar neurons?
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What type of neurons interconnect different neurons and are involved in complex responses?
What type of neurons interconnect different neurons and are involved in complex responses?
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Which type of receptor provides information about external environmental sensations?
Which type of receptor provides information about external environmental sensations?
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What is not a characteristic of neuroglia?
What is not a characteristic of neuroglia?
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Neural stem cells are primarily ___ in the adult nervous system.
Neural stem cells are primarily ___ in the adult nervous system.
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Study Notes
Nervous System Introduction
- Two systems maintain homeostasis: nervous and endocrine
- Nervous system responds quickly, but briefly
- Endocrine system responds slowly, but lasts longer
- Nervous system coordinates body position, eye movements, and internal processes
- Nervous system monitors internal/external environment, and issues commands for homeostasis
- Nervous system activity patterns can shift quickly
Anatomical and Functional Divisions
- Nervous system has three main functions: monitors internal/external environments, integrates sensory information, coordinates organ system responses
- Two major anatomical divisions:
- Central Nervous System (CNS): brain and spinal cord, processes sensory data and motor commands, seat of higher functions (e.g., intelligence, memory, emotion)
- Peripheral Nervous System (PNS): all neural tissue outside the CNS, communicates between CNS and body
- Two functional divisions of PNS:
- Afferent division: brings sensory information to CNS from receptors (sensory structures); detects internal and external changes
- Efferent division: carries motor commands from CNS to muscles and glands (effectors); causes action in the target tissues or organs
- Efferent division has two parts:
- Somatic nervous system (SNS): controls skeletal muscle contractions (voluntary and involuntary); e.g., lifting a glass, or pulling hand back from a hot stove (reflex)
- Autonomic nervous system (ANS): regulates smooth muscle, cardiac muscle, and glandular secretions at subconscious level; has sympathetic (speeds up heart rate) and parasympathetic (slows heart rate) divisions, which often have opposing effects
Neurons and Neuroglia
- Neurons: basic functional units of nervous system; communicate with other neurons and cells
- Neuroglia: regulate environment around neurons, provide support, and act as phagocytes (far more numerous than neurons); most can divide
- Neuron structure (representative neuron): cell body, dendrites, axon, axon terminals
Neuron Structure
- Neuron cell body contains large, round nucleus with a nucleolus; organelles that provide energy and synthesize compounds
- Cytoplasm also contains numerous mitochondria, ribosomes, and rough endoplasmic reticulum (RER)
- Clusters of RER and free ribosomes are called Nissl bodies
- Dendrites and a single axon project from the cell body
- Dendrites and cell body plasma membrane are sensitive to stimulation
- Electric signals are generated (action potentials) at the axon hillock and travel along the axon
- Axon may branch into collaterals, which end in axon terminals (synaptic terminals or knobs)
- Synapse: site of communication between neurons
- Most CNS neurons cannot divide due to lack of centrioles
Neuron Classification
-
Multipolar neurons: two or more dendrites, and one axon
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Unipolar neurons: dendrites and axon are continuous; cell body lies off to one side; most sensory neurons in PNS, with long axons
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Bipolar neurons: one dendrite, one axon, cell body between them; small and rare; found in special sense organs (vision, smell, hearing)
Functional Neuron Classification
- Sensory neurons: afferent; receive information from sensory receptors, relayed to other neurons in CNS
- Somatic sensory receptors: detect external environment or position
- External receptors: detect touch, pressure, pain, temperature, taste, smell, sight, equilibrium, hearing
- Proprioceptors: monitor position and movement of skeletal muscles and joints
- Visceral receptors: monitor digestive, respiratory, cardiovascular, urinary, and reproductive systems; detect distension, deep pressure, and pain
- Motor neurons: efferent; carry instructions from CNS to effectors (other tissues, organs, or organ systems); SNS - skeletal muscles; ANS – smooth muscle, cardiac muscles, glands
- Interneurons: association neurons; entirely within CNS; interconnect other neurons; responsible for distributing sensory info and coordinating motor activity
Neuroglia of CNS
- Astrocytes: largest and most numerous neuroglia; maintain blood-brain barrier, regulate chemical environment, wrap around capillaries
- Oligodendrocytes: smaller cell bodies than astrocytes; have sheet-like processes that wrap around axons; myelination of several axons
- Microglia: smallest and least numerous; phagocytic cells; derived from white blood cells; protect against pathogens
- Ependymal cells: simple cuboidal epithelial cells; line cavities in CNS filled with CSF; some produce CSF, others circulate it with cilia
Organization of neurons in nervous system
- PNS: neuron cell bodies in ganglia, surrounded by satellite cells; axons bundled in nerves (spinal, cranial)
- CNS: collection of neuron cell bodies (gray matter) with a common function is called a center; center with a discrete boundary (nucleus); white matter contains bundles of axons (tracts)
Demyelination disorders
- Demyelination: progressive destruction of myelin sheaths; loss of sensation, and motor control (e.g., multiple sclerosis (MS))
Action Potentials
- Action potential: propagated change in membrane potential of excitable cells; involves opening and closing of voltage-gated channels in response to a graded potential
- All-or-none principle: given stimulus triggers a typical action potential or none at all
- Resting membrane potential: -70 mV ; cell interior negatively charged relative to extracellular fluid; maintained by ion pumps and ion channels
- Depolarization: shift in membrane potential toward 0 mV; opening of sodium channels speeds up sodium ion movement into the cell
- Repolarization: return to resting potential; opening of potassium channels increases potassium ion movement out of cell; opening of sodium channels is blocked (refractory period)
- Generation of action potentials involves graded depolarization, opening of voltage-gated sodium channels, inactivation of sodium channels, activation of potassium channels, return to resting potential
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Description
Test your knowledge on the nervous system and its functions in this quiz. Explore key concepts including the structure, divisions, and physiological processes involved in nervous system responses. Perfect for students studying biology and looking to reinforce their understanding of this essential topic.