Biology Chapter: Macromolecules and Reactions
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Questions and Answers

Which type of molecule is NOT a polymer of smaller subunit molecules?

  • Carbohydrates
  • Proteins
  • Nucleic acids
  • Lipids (correct)
  • Cells decrease entropy without expending energy.

    False (B)

    What type of reaction links monomers together to form polymers, releasing a water molecule?

    dehydration reaction

    Proteins are made up of ______.

    <p>amino acids</p> Signup and view all the answers

    Match the biological molecules with their primary function:

    <p>Carbohydrates = Energy storage and structural support Lipids = Energy storage and membrane formation Proteins = Performing cellular functions Nucleic acids = Information storage and short-term energy storage</p> Signup and view all the answers

    Which of the listed chemical features are associated with carbohydrates?

    <p>Linear chain or ring (C)</p> Signup and view all the answers

    Phosphodiester bonds link amino acids together to form proteins.

    <p>False (B)</p> Signup and view all the answers

    According to the diagram, what does 'β' indicate regarding the position of an OH group attached to a carbon in the ring?

    <p>Above the plane of the ring (C)</p> Signup and view all the answers

    A glycosidic β 1->4 linkage involves a condensation reaction between a β1 OH on sugar A and an α4 OH on sugar B.

    <p>False (B)</p> Signup and view all the answers

    What type of reaction occurs between two sugars to form a glycosidic linkage?

    <p>condensation reaction</p> Signup and view all the answers

    Positions of the OH groups attached to each carbon in the ring are described as being either UP (above the plane of the ring) = ______.

    <p>β</p> Signup and view all the answers

    Match the following descriptions with the correct term:

    <p>α = OH group below the plane of the ring β = OH group above the plane of the ring Condensation reaction = Reaction that releases water</p> Signup and view all the answers

    Based on the content, what is the primary structural difference between starch and cellulose that accounts for human digestibility?

    <p>The linkage types between glucose molecules differ in starch and cellulose. (A)</p> Signup and view all the answers

    Given a sugar molecule has multiple OH groups located at various positions throughout the structure, linked sugars are capable of forming a limited array of branched polysaccharide structures.

    <p>False (B)</p> Signup and view all the answers

    How many different ways are there to form D-glucose disaccharides, according to the content provided?

    <p>11</p> Signup and view all the answers

    The position of the OH groups attached to each carbon in the ring are described as being either DOWN (below the plane of the ring) = ______.

    <p>α</p> Signup and view all the answers

    Which type of linkage can humans digest in starch?

    <p>α linkages (D)</p> Signup and view all the answers

    Lipids are hydrophilic membrane barriers.

    <p>False (B)</p> Signup and view all the answers

    What chemical feature do triglycerides have?

    <p>hydrocarbon chains with polar COOH at one end</p> Signup and view all the answers

    Phospholipids are considered to be ______ in chemical nature.

    <p>amphipathic</p> Signup and view all the answers

    In GM2 gangliosides, what replaces the phosphate/polar head group found in phospholipids?

    <p>Carbohydrate (D)</p> Signup and view all the answers

    What enzyme mutation causes Tay-Sachs disease?

    <p>β-hexosaminidase A (C)</p> Signup and view all the answers

    What does the 1st Law of Thermodynamics state?

    <p>The amount of energy in a system is constant. (A)</p> Signup and view all the answers

    Cells operate as isolated systems according to the laws of thermodynamics.

    <p>False (B)</p> Signup and view all the answers

    Amino acids are building blocks of ______.

    <p>proteins</p> Signup and view all the answers

    Match the following terms to their descriptions:

    <p>Triglyceride = Energy storage in animal cells Phospholipid = Amphipathic molecule forming cell membranes Amino acid = Building block of proteins GM2 Ganglioside = Involved in cell-cell communication and neuronal plasticity</p> Signup and view all the answers

    What characterizes a spontaneous reaction in the context of thermodynamics?

    <p>A reaction that will occur without a net addition of energy.</p> Signup and view all the answers

    According to the 2nd Law of Thermodynamics, all processes in the universe tend to increase __________.

    <p>entropy</p> Signup and view all the answers

    Match the thermodynamic laws to their descriptions:

    <p>1st Law = Energy cannot be created or destroyed, only transformed 2nd Law = Processes increase disorder (entropy) and decrease usable energy Spontaneous Reaction = Occurs without net addition of energy</p> Signup and view all the answers

    Which of the following amino acids are classified as acidic?

    <p>Aspartic acid (A)</p> Signup and view all the answers

    All amino acid side chains are nonpolar and do not ionize at neutral pH.

    <p>False (B)</p> Signup and view all the answers

    What does ATP stand for?

    <p>Adenosine triphosphate</p> Signup and view all the answers

    The basic amino acids include histidine, lysine, and __________.

    <p>arginine</p> Signup and view all the answers

    Match the following amino acids with their classification:

    <p>Aspartic acid = Acidic Glutamic acid = Acidic Histidine = Basic Lysine = Basic</p> Signup and view all the answers

    Which type of chemical features do nucleotides exhibit?

    <p>Uniform chemical structure with side group variability (B)</p> Signup and view all the answers

    Nucleotides are only found as components of DNA and cannot act as energy carriers.

    <p>False (B)</p> Signup and view all the answers

    What type of order do living things create and maintain?

    <p>Order in a universe tending to greater disorder</p> Signup and view all the answers

    The pK value represents the pH at which __________ of all molecules of an ionizable substance are charged.

    <p>half</p> Signup and view all the answers

    Match the following compounds with their roles:

    <p>Amino acids = Building blocks of proteins Nucleotides = Building blocks of nucleic acids ATP = Short-term energy carrier DNA = Genetic material</p> Signup and view all the answers

    Flashcards

    Monomers

    Small subunit molecules that link to form polymers.

    Polymers

    Large molecules made from linked monomers.

    Carbohydrates

    Molecules made of sugar monomers for energy and support.

    Lipids

    Fatty acids linked to glycerol, used for energy storage.

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    Proteins

    Composed of amino acids, they perform most cellular functions.

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    Nucleic acids

    Polymers of nucleotides used for information storage.

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    Condensation reactions

    Reactions that link monomers to form polymers, releasing water.

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    α and β configurations

    Different orientations of OH groups on sugar carbons; β is up, α is down.

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    Glycosidic linkage

    The bond formed between two sugar molecules during a condensation reaction.

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    Polysaccharide structure

    Large carbohydrate molecules formed by multiple sugar units linking together.

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    Starch vs Cellulose

    Starch is digestible energy storage; cellulose is non-digestible structural support.

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    D-Glucose disaccharides

    Different combinations of two glucose units; 11 ways to link them.

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    Positions of OH groups

    The locations of OH groups on a sugar determine its properties and bonds.

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    Branched polysaccharides

    Carbohydrates with branching structures formed by multiple glycosidic linkages.

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    Energy storage vs Structural molecules

    Energy storage molecules, like starch, are digestible; structural ones, like cellulose, are not.

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    Starch vs Cellulose Digestion

    We can digest starch but not cellulose due to enzyme specificity.

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    Triglycerides

    Fats that store energy in animals, composed of glycerol and fatty acids.

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    Amphipathic

    Molecules having both hydrophobic and hydrophilic parts.

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    Gangliosides

    Lipids similar to phospholipids with a carbohydrate head group, important for communication.

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    GM2 Ganglioside

    A type of ganglioside involved in cell communication and plasticity.

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    Tay-Sachs Disease

    Genetic disorder caused by GM2 accumulation due to a mutation in an enzyme.

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    b-Hexosaminidase A

    An enzyme that metabolizes GM2; its mutation causes Tay-Sachs disease.

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    Amino Acids

    Building blocks of proteins with a uniform structure and variable side groups.

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    Protein Structure Directionality

    Amino acids have directionality from amino terminus to carboxyl terminus.

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    1st Law of Thermodynamics

    Energy in a closed system is constant; it cannot be created or destroyed, only converted.

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    2nd Law of Thermodynamics

    All processes increase disorder (entropy); usable energy decreases over time.

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    Spontaneous Reaction

    A reaction that occurs without a net addition of energy.

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    Energetically Favorable Reactions

    Reactions that decrease available energy and occur spontaneously.

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    Cells and Energy Exchange

    Cells are not isolated; they exchange energy with their environment to maintain order.

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    Ionizable amino acids

    Amino acids that can gain or lose protons at physiological pH.

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    Acidic amino acids

    Amino acids that donate protons, increasing acidity; examples include aspartate and glutamate.

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    Basic amino acids

    Amino acids that accept protons, making them positively charged; includes histidine, lysine, arginine.

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    pK value

    The pH at which half of an ionizable substance's molecules are charged.

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    Nucleotides

    Building blocks of nucleic acids, involved in energy transfer and signaling.

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    ATP

    Adenosine triphosphate, the main energy carrier in cells.

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    Chemical structure of nucleotides

    Nucleotides have a uniform structure but vary in their nitrogenous base.

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    Polar nature of nucleotides

    Nucleotides are polar molecules that have charged areas associated with their structure.

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    Order in living things

    Living organisms maintain order, counteracting the tendency toward disorder in nature.

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    Functions of proteins

    Proteins perform most cellular functions, influenced by their amino acid sequences.

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    Study Notes

    Biological Molecules: Building Blocks of Cells

    • Cells are composed of a specific set of small carbon-based molecules, fundamentally similar across all living organisms.
    • Essential molecules within cells are polymers of smaller subunits (monomers).
    • Carbohydrates, composed of sugar monomers, function as energy storage and structural components within cells.
    • Lipids, made from fatty acids (often linked to glycerol), serve as energy storage and assemble membranes.
    • Proteins, comprised of amino acids, carry out most cellular functions.
    • Nucleic acids, from nucleotide monomers, store genetic information and provide short-term energy.
    • Cells maintain order (reduce entropy) at the cost of energy expenditure.

    Chemical Composition of a Bacterial Cell (Approximate)

    • Water comprises 70% of a bacterial cell's weight.
    • Inorganic ions account for 1%.
    • Sugars and precursors make up 1%.
    • Amino acids and precursors total 0.4%.
    • Nucleotides and precursors equal 0.4%.
    • Fatty acids and precursors are found at 1%.
    • Other small molecules add up to around 0.2%.
    • Macromolecules (proteins, nucleic acids, and polysaccharides) constitute 26%.
    • Roughly 3000 different types of macromolecules exist.
    • There are approximately 250 types of sugars and precursors.
    • About 100 types are seen in amino acids and precursors.
    • Approximately 100 types of molecules are found in nucleotides and precursors.
    • Around 50 types exist for fatty acid and other precursors.

    Components of Cells

    • Water (70%) is the primary component of cells.
    • Other small molecules (~300) account for a smaller proportion.
    • Macromolecules (proteins, nucleic acids, polysaccharides) account for about 3000 different molecules.
    • These molecules include proteins (15%), polysaccharides (2%), small molecules/ions (4%), phospholipids (2%), DNA/RNA (7%).

    Formation of Polymers

    • Monomers are joined to form polymers through dehydration (condensation) reactions.
    • A water molecule is removed during this process.

    Carbohydrates

    • Carbohydrate structures are generally linear chains or ring structures.
    • These structures have multiple hydroxyl (OH) groups attached.
    • Sugars undergo various linkages, each with numbered carbons (starting from the oxygen in the ring).
    • Key linkage classifications include alpha (α) and beta (β), based on the OH group's position.

    Lipids

    • Lipids have hydrocarbon tails and polar carboxyl groups (COOH).
    • These properties make lipids hydrophobic.
    • Triglycerides are a form of lipid used for energy storage.
    • Phospholipids, a specific type of lipid, form cell membranes due to their amphipathic nature (having both hydrophilic and hydrophobic regions).

    Amino Acids

    • Amino acids have a uniform structure with an amino group (-NH2) and a carboxyl group (-COOH) bonded to a central carbon atom.
    • The side chains (R groups) vary, defining each unique type of amino acid.
    • Amino acids readily ionize at neutral pH.
    • Amino acids can be acidic, basic, or electrically charged among other properties.

    Nucleotides

    • Nucleotides have a uniform structure consisting of a nitrogenous base, a five-carbon sugar (ribose or deoxyribose), and a phosphate group.
    • Nitrogenous bases vary, with notable examples being adenine and others.
    • They play vital roles as energy carriers and building blocks of nucleic acids (DNA and RNA).
    •   Adenosine triphosphate (ATP) is an important short-term energy carrier in cells. 

    Cells and Thermodynamics

    • Cells increase biological order, but this contradicts the second law of thermodynamics which holds that the universe tends to increasing disorder (entropy).
    • Cells are not isolated, they exchange energy and matter with their surroundings.
    • Energy input is used to generate order within cells.
    • Some energy converts into heat which increases disorder in the surrounding environment.
    • "Spontaneous" reactions proceed without net energy input, not necessarily instantaneously.

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    Test your knowledge on biological macromolecules, their structures, and the reactions that form them. This quiz covers proteins, carbohydrates, and the types of bonds that link monomers together. Perfect for biology students seeking to enhance their understanding of molecular biology.

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