Biology Chapter 18: Cardiovascular System
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Questions and Answers

Which of the following is NOT a characteristic of blood?

  • It protects against disease.
  • It transports oxygen and carbon dioxide.
  • It helps maintain electrolyte balance. (correct)
  • It regulates body temperature.
  • During centrifugation, what comprises the buffy coat?

  • Only plasma.
  • Only red blood cells.
  • White blood cells and platelets. (correct)
  • Plasma and red blood cells.
  • What is the role of erythropoietin in the process of erythropoiesis?

  • It stimulates the release of white blood cells.
  • It inhibits the breakdown of red blood cells.
  • It triggers the formation of platelets.
  • It promotes the formation of red blood cells. (correct)
  • Which of the following is NOT a type of granulocyte?

    <p>Lymphocytes. (D)</p> Signup and view all the answers

    What is the primary function of platelets in the blood?

    <p>Form blood clots. (C)</p> Signup and view all the answers

    Which of the following blood types is considered the universal donor?

    <p>O- (C)</p> Signup and view all the answers

    What is a differential count in hematology?

    <p>A measurement of the percentage of each type of white blood cell. (A)</p> Signup and view all the answers

    What is the first step in hemostasis, the process of stopping bleeding?

    <p>Vascular spasm. (C)</p> Signup and view all the answers

    What is the primary function of the pericardium?

    <p>To protect and anchor the heart (C)</p> Signup and view all the answers

    Which of the following is NOT a component of the heart's conduction system?

    <p>Aortic valve (D)</p> Signup and view all the answers

    What is the role of intercalated discs in cardiac muscle?

    <p>They allow rapid communication and coordination between cells (D)</p> Signup and view all the answers

    During which phase of an action potential in cardiac muscle does the plateau occur?

    <p>Repolarization (C)</p> Signup and view all the answers

    Which of the following is the correct sequence of blood flow through the heart?

    <p>Right atrium, right ventricle, left atrium, left ventricle (D)</p> Signup and view all the answers

    Which of the following is a characteristic of the sympathetic nervous system's influence on the heart?

    <p>Increases heart rate (C)</p> Signup and view all the answers

    What is the primary function of the pulmonary circulation?

    <p>To exchange gases between the blood and the lungs (C)</p> Signup and view all the answers

    What is the main function of the SA node in the heart?

    <p>To generate electrical impulses that control heart rate (D)</p> Signup and view all the answers

    What primary factor contributes to the resistance of blood flow in the circulatory system?

    <p>Blood viscosity (A)</p> Signup and view all the answers

    Which hormone is primarily responsible for increasing blood pressure through fluid retention and vasoconstriction?

    <p>Angiotensin II (B)</p> Signup and view all the answers

    What is the correct formula for calculating mean arterial pressure (MAP)?

    <p>MAP = Diastolic pressure + 1/3 (Systolic pressure - Diastolic pressure) (D)</p> Signup and view all the answers

    How does blood pressure change in the systemic circulation when resistance increases?

    <p>Blood pressure increases due to reduced flow (C)</p> Signup and view all the answers

    Which statement correctly contrasts blood pressure in the arteries versus veins?

    <p>Arterial blood pressure is higher due to proximity to the heart (A)</p> Signup and view all the answers

    What are the five phases of the cardiac cycle?

    <p>Atrial contraction, isovolumetric contraction, ventricular ejection, isovolumetric relaxation, diastolic filling (D)</p> Signup and view all the answers

    Which three variables influence stroke volume?

    <p>Preload, afterload, contractility (D)</p> Signup and view all the answers

    What is cardiac output, and how is it defined?

    <p>The volume of blood the heart pumps in one minute; heart rate multiplied by stroke volume (B)</p> Signup and view all the answers

    What role do chronotropic agents play in heart rate regulation?

    <p>They increase heart rate and can be influenced by intrinsic factors (A)</p> Signup and view all the answers

    What are the distinguishing features of capillaries compared to arteries and veins?

    <p>Capillaries are singularly layered to allow for exchange with tissues (B)</p> Signup and view all the answers

    What process is most significantly involved in the exchange of nutrients and waste in capillaries?

    <p>Diffusion (A)</p> Signup and view all the answers

    How does the myogenic response help maintain normal blood flow through a tissue?

    <p>It allows for immediate dilation or constriction of vessels in response to blood flow changes (B)</p> Signup and view all the answers

    In terms of blood vessel pathways, what distinguishes alternative pathways from simple pathways?

    <p>Alternative pathways provide multiple routes for blood to reach the same tissue (A)</p> Signup and view all the answers

    Flashcards

    Total Blood Flow

    The volume of blood that circulates through the body in a given period.

    Blood Pressure Gradient

    The difference in blood pressure between two points in the circulatory system.

    Resistance in Blood Flow

    A measure of the opposition to blood flow in vessels, influenced by viscosity, length, and radius.

    Mean Arterial Pressure (MAP)

    The average pressure in a person's arteries during one cardiac cycle.

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    Renin-Angiotensin System

    A hormone system that regulates blood pressure and fluid balance by adjusting blood vessel constriction.

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    Platelet response to damage

    When platelets encounter damage, they adhere to the site, aggregate, and release chemicals to promote clotting.

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    Coagulation

    The process of blood clotting involving platelets and clotting factors to stop bleeding.

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    Intrinsic pathway

    Part of coagulation activated by internal damage to blood vessels, involving a series of factors (like XII, XI, IX, VIII).

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    Extrinsic pathway

    Part of coagulation activated by external trauma, primarily involving tissue factor (TF) and factor VII.

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    Common pathway

    The convergence of intrinsic and extrinsic pathways leading to the activation of prothrombin to thrombin, forming a blood clot.

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    Cardiovascular system function

    The cardiovascular system's primary function is to transport blood, nutrients, gases, and wastes throughout the body.

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    Heart wall layers

    The three heart wall layers are the epicardium, myocardium, and endocardium, each serving distinct functions.

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    Electrical conduction in the heart

    The heart's conduction system generates and spreads electrical impulses, causing the heart to contract rhythmically.

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    Cardiac Cycle Phases

    Five distinct phases of the heartbeat, including diastole and systole.

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    Cardiac Output

    The volume of blood pumped by the heart per minute.

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    Cardiac Reserve

    The difference between resting and maximum cardiac output.

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    Chronotropic Agents

    Substances that alter the heart rate by affecting the pacemaker.

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    Stroke Volume Influencers

    Three variables: preload, afterload, and contractility that determine stroke volume.

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    Capillary Structure

    Capillaries are thin-walled vessels essential for gas and nutrient exchange.

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    Net Filtration Pressure (NFP)

    The difference between hydrostatic pressure and osmotic pressure in capillaries.

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    Vasodilator vs Vasoconstrictor

    Vasodilators widen blood vessels; vasoconstrictors narrow them.

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    Functions of Blood

    Blood carries oxygen, nutrients, hormones, and waste, plays a role in immune response and regulates body temperature.

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    Components of Centrifuged Blood

    A centrifuged blood sample contains plasma, erythrocytes, and the buffy coat (leukocytes and platelets).

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    Hematocrit

    Hematocrit is the percentage of blood volume occupied by red blood cells; clinical usage may differ from medical definition based on measurement context.

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    Colloid Osmotic Pressure

    Colloid osmotic pressure is the pressure exerted by plasma proteins that draws water into the circulatory system, affecting fluid balance.

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    Types of Plasma Proteins

    Major plasma proteins include albumins (regulate osmotic pressure), globulins (immune function), and fibrinogen (blood clotting).

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    Erythropoiesis Process

    Erythropoiesis is the production of red blood cells, stimulated by erythropoietin, mainly in the bone marrow.

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    Granulocytes vs Agranulocytes

    Granulocytes (neutrophils, eosinophils, basophils) contain granules and are primarily involved in immune responses; agranulocytes (monocytes, lymphocytes) lack these granules.

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    Vascular Spasm in Hemostasis

    Vascular spasm is the immediate constriction of blood vessels after injury, reducing blood flow; it is the first step in hemostasis.

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    Study Notes

    Chapter 18: Cardiovascular System: Blood

    • Blood Functions: Blood transports oxygen, nutrients, hormones, and waste products; regulates body temperature and pH; and protects against infection.

    • Six Characteristics of Blood: (and their significance to health and homeostasis)

      • High Viscosity: Thick, sticky consistency resists rapid flow
      • Temperature: Higher than body temperature, aiding in heat distribution
      • Slightly Alkaline pH: Maintains a stable environment for cells
      • Volume: Roughly 8% of total body weight, regulating blood pressure and volume
      • Color: Red due to hemoglobin, indicating oxygen levels
      • Solute composition: Essential for osmotic balance and pH regulation
    • Components of Centrifuged Blood Sample:

      • Plasma: Liquid component, primarily water, dissolved proteins, and other solutes.
      • Buffy Coat: Thin layer of leukocytes (white blood cells) and platelets.
      • Red Blood Cells (Erythrocytes): Dense, red layer containing hemoglobin for oxygen transport.
    • Hematocrit: Percentage of red blood cells in a blood sample. Medical definition differs from clinical usage where hematocrit may not be adjusted for sample volume.

    • Three Formed Elements:

      • Erythrocytes: Red blood cells, major component in blood
      • Leukocytes: White blood cells, crucial for immune defense, less abundant compared to erythrocytes.
      • Platelets: Cell fragments, critical in blood clotting.
    • Colloid Osmotic Pressure: Pressure exerted by plasma proteins; crucial for water balance.

    • Plasma Proteins:

      • Albumin: Maintains colloid osmotic pressure, transports hormones, and fatty acids.
      • Globulins: Involved in immune functions and transporting various substances.
      • Fibrinogen: Essential for blood clot formation.
    • Plasma Solutes: Nutrients, proteins, electrolytes, cellular waste products, gases (oxygen, carbon dioxide).

    • Hematopoiesis: Blood cell formation in red bone marrow. Hematopoietic stem cells differentiate into various blood cell lineages. Colony-stimulating factors (CSFs) are vital.

    • Erythropoiesis: Production of red blood cells in response to oxygen needs. Hormones like EPO (erythropoietin) stimulate erythrocyte production.

    • Leukopoiesis: Formation of white blood cells (granulocytes, monocytes, lymphocytes).

    • Thrombopoiesis: Platelet production.

    • Erythrocyte Structure: Biconcave discs for optimal surface area for gas exchange.

    • Erythrocyte Production Stimulation: Reduced oxygen (low O2) levels

    • Erythrocyte Component Recycling: Breakdown of aged or damaged erythrocytes by the spleen and liver. Hemoglobin components are recycled.

    • Blood Types: Various blood types (A, B, AB, O) based on antigens on red blood cells influence recipient compatibility.

    Chapter 19: Cardiovascular System: The Heart

    • Heart Function: Pumps blood throughout the body, driving circulation.

    • Heart Structure and Function: Four chambers (two atria, two ventricles) with valves for unidirectional blood flow

    • Pulmonary vs. Systemic Circulation: Pulmonary circulation carries deoxygenated blood to the lungs and returns oxygenated blood to the heart. Systemic circulation pumps oxygenated blood to the body and returns deoxygenated blood to the heart.

    • Heart Location: Within the thoracic cavity, slightly left of the midline.

    • Pericardium: Double-walled sac surrounding the heart. Surfaces secrete fluid for friction reduction.

    • Heart Wall Layers: Epicardium (outer), myocardium (middle muscle layer), endocardium (inner).

    • Heart Valves: Prevent backflow; Atrioventricular (tricuspid and mitral) and semilunar (pulmonary and aortic) valves).

    • Coronary Arteries: Supply the heart muscle with oxygenated blood.

    • Coronary Veins: Collect deoxygenated blood from the heart muscle.

    • Cardiac Muscle: Intercalated discs allow rapid depolarization, crucial for coordinated contractions.

    • Conduction System: SA node (pacemaker), AV node, bundle of His, Purkinje fibers coordinate heart contraction.

    • Innervation: Sympathetic and parasympathetic systems alter heart rate.

    Chapter 20: Cardiovascular System: Vessels and Circulation

    • Blood Vessel Tunics: Intima (inner), media (middle muscle layer), and externa (outer).

    • Arteries vs. Capillaries vs. Veins: Structural differences reflect function; e.g. thicker muscle in arteries, thin walls in capillaries, valves in veins.

    • Capillaries: Sites of exchange between blood and tissues.

    • Veins: Return blood to the heart, aided by valves preventing backflow.

    • Blood Flow in Capillaries: Blood flow is slow for optimal gas and nutrient exchange.

    • Arterial/Venous Pressure: Blood flow is related to the pressure difference between arterial and venous ends of a vessel.

    • Lymphatic System: Assists with fluid balance and plays a role in immune response.

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    Description

    Explore the critical functions and characteristics of blood in Biology Chapter 18. Understand how blood transportation, regulation, and protection mechanisms work to maintain homeostasis. Learn about the components of a centrifuged blood sample and their significance in health.

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