39 Questions
What is the prevalence of peripartum onset major depressive disorder in the second trimester?
12.8%
Which antidepressant did Anne have the best response to?
Duloxetine
What is the leading cause of disease burden worldwide for people of childbearing age?
Depression
How many symptoms are required for a diagnosis of Major Depressive Episode according to DSM 5?
5
What happened to Anne after she abruptly stopped taking duloxetine?
She became acutely depressed
What percentage of pregnant persons will experience a depressive episode in the perinatal period?
8%
In a Major Depressive Episode, what symptom must be present among the five or more symptoms?
'Anhedonia' - diminished interest or pleasure
How old is Anne's child who has Autism Spectrum Disorder?
5
What are the common symptoms of depression during pregnancy mentioned in the text?
Disturbed sleep patterns, energy changes, and feelings of worthlessness
Why is diagnosing and treating depression during pregnancy considered crucial according to the text?
To prevent impaired bonding with the newborn
What are the risks of untreated depression in pregnancy to the developing fetus or infant, as mentioned in the text?
Increased risk of preterm birth and long-term cognitive effects
What potential effect of maternal anxiety between 12-22 weeks gestation is associated with ADHD and child anxiety, as per the text?
Externalizing behaviours in children
What is a symptom unique to postpartum depression as highlighted in the text?
Feelings of worthlessness related to parenting
Which factor is mentioned as a biological risk factor for perinatal mood disorders in the text?
Genetic and epigenetic factors
What is the DSM-5 defined onset period for postpartum depression?
During pregnancy or within 4 weeks following delivery
What is the spectrum of postpartum mood changes as per the text?
>50% at risk for MDD
What is a common reason why parents and their partners refuse medication during pregnancy and breastfeeding?
Concerns about potential teratogenicity
Which type of therapy focuses on areas such as grief, role transition, and interpersonal role disputes in treating depressed pregnant and postpartum parents?
Interpersonal Psychotherapy (IPT)
What might lead to considering moving to pharmacological interventions for perinatal depression?
Inability to carry out daily activities
What is recommended regarding the use of psychotropic medications in pregnancy?
Use the minimum number at the lowest effective dose
What is a potential risk associated with abruptly stopping or lowering dose of psychotropic medications before delivery?
Neonatal complications such as respiratory distress
What is an important consideration when using SSRIs in pregnancy during the third trimester?
Increase the dosage to prevent neonatal complications
What is a common concern related to antidepressants and Autism Spectrum Disorders (ASDs) mentioned in the text?
Increased risk of ASDs with antidepressant use
What is stated about the relationship between SSRIs and teratogenicity in pregnancy?
No increased risk of teratogenicity over background risk associated with SSRIs
What is a common biological risk factor for perinatal major depression?
Breastfeeding difficulties
When should screening for perinatal depression occur postpartum?
Between 6-16 weeks postpartum
What is the purpose of using the Edinburgh Postnatal Depression Scale (EPDS)?
To screen for postpartum depression
What psychosocial risk factor is associated with perinatal depression?
Socio-economic status
What does a high EPDS score indicate?
Risk of maternal-infant interaction issues
What should be considered if suicidal ideation is detected during screening with the EPDS?
Immediate hospitalization
How does chronic maternal depression impact the child?
Higher rates of anxiety disorders
What is a potential implication of postpartum depression for the birth parent?
Risk of suicide and relationship disruption
What is the absolute risk of Postpartum Psychosis happening in first-time moms?
1-2%
Which symptom is NOT associated with Postpartum Psychosis?
Memory Loss
What is the relative risk for the first onset of Affective Psychosis within 4 weeks after delivery compared to other periods in a woman's life?
23 times higher
Which mental illness is NOT listed as a Co-Morbid Illness with postpartum concerns?
Schizophrenia
What is considered a psychiatric emergency that requires hospitalization?
Hallucinations
'Breast is Best' in breastfeeding only if:
'Birth parent and baby will be healthy'
'Non-exposure' in relation to medication during pregnancy means:
'Exposed to medication'
Explore the biological and psychosocial risk factors associated with perinatal major depression. Topics include prior history of MDD/PMDD/PPD, psychiatric illness in family members, breastfeeding difficulties, lack of social support, and more.
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