Podcast
Questions and Answers
What is one feature that a successful control system of the cell cycle should possess?
What is one feature that a successful control system of the cell cycle should possess?
- Lack of backup mechanisms
- A clock/timer to provide a fixed amount of time for each event (correct)
- Trigger events randomly
- Ability to skip events if needed
Why is having a mechanism to ensure events are only triggered once per cycle important?
Why is having a mechanism to ensure events are only triggered once per cycle important?
- To speed up the cell cycle
- To allow events to repeat multiple times
- To prevent replication errors (correct)
- To increase adaptability
What role do checkpoints play in the cell cycle?
What role do checkpoints play in the cell cycle?
- To skip DNA replication
- To trigger events randomly
- To speed up mitosis
- To prevent the progression of the next phase if the previous event is incomplete (correct)
Why is adaptability an important feature of the cell-cycle control system?
Why is adaptability an important feature of the cell-cycle control system?
What happens if DNA replication is not complete in the cell cycle?
What happens if DNA replication is not complete in the cell cycle?
Why is having an all-or-none switch that triggers events important in the cell-cycle control system?
Why is having an all-or-none switch that triggers events important in the cell-cycle control system?
What happens if chromosomes are not properly attached to the mitotic spindles?
What happens if chromosomes are not properly attached to the mitotic spindles?
How do checkpoints generally operate?
How do checkpoints generally operate?
Why are negative signals important in the context of chromosome attachment to the mitotic spindle?
Why are negative signals important in the context of chromosome attachment to the mitotic spindle?
What evidence supports the assertion that cell cycle checkpoints operate through negative signals?
What evidence supports the assertion that cell cycle checkpoints operate through negative signals?
What controls the activity of Cyclin-dependent Kinases (CDKs) throughout the cell cycle?
What controls the activity of Cyclin-dependent Kinases (CDKs) throughout the cell cycle?
Why do cells with defects in checkpoints often accumulate mutations?
Why do cells with defects in checkpoints often accumulate mutations?