Biochemistry of Vitamins
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Questions and Answers

Which vitamins are classified as fat-soluble vitamins?

  • Vitamin E, Vitamin B1, Vitamin D, Vitamin A
  • Vitamin A, Vitamin D, Vitamin E, Vitamin K (correct)
  • Vitamin C, Vitamin B12, Vitamin D, Vitamin E
  • Vitamin A, Vitamin B6, Vitamin C, Vitamin K
  • What is a primary source of active vitamin A?

  • Fruits and vegetables
  • Whole grains
  • Meat and fish liver oils (correct)
  • Dairy products only
  • Which function does vitamin A primarily serve in the body?

  • Protein synthesis
  • Energy production
  • Blood clotting
  • Vision (correct)
  • Which vitamin acts as a precursor to vitamin A from plant sources?

    <p>Beta-carotene</p> Signup and view all the answers

    What is a primary effect of vitamin A deficiency?

    <p>Night blindness</p> Signup and view all the answers

    Which vitamin is primarily responsible for the function of rod cells in dim light vision?

    <p>Vitamin A</p> Signup and view all the answers

    What condition may result from a deficiency of vitamin A in the eye?

    <p>Night blindness</p> Signup and view all the answers

    Which of the following vitamins does NOT yield energy but facilitates energy-yielding reactions?

    <p>Vitamin D</p> Signup and view all the answers

    What is one of the roles of retinoic acid in the body?

    <p>Synthesis of glycoproteins</p> Signup and view all the answers

    Which function is primarily associated with water-soluble vitamins?

    <p>Synthesis of collagen and neurotransmitters</p> Signup and view all the answers

    Where can vitamin D3 be primarily obtained from?

    <p>Fish liver oils</p> Signup and view all the answers

    Which of these vitamins is primarily obtained from animal sources?

    <p>Vitamin B12</p> Signup and view all the answers

    Which of the following is a symptom of vitamin A deficiency?

    <p>Skin roughness</p> Signup and view all the answers

    How is vitamin D3 synthesized in the skin?

    <p>Conversion of cholesterol by UV rays</p> Signup and view all the answers

    What effect does retinoic acid have on bone health?

    <p>It accelerates bone growth</p> Signup and view all the answers

    Which of the following fruits is known for its high levels of carotenes?

    <p>Carrot</p> Signup and view all the answers

    What condition is primarily caused by hypercalcemia due to abnormal calcification?

    <p>Kidney stones</p> Signup and view all the answers

    Which type of tocopherol is known to be the most potent?

    <p>Alpha-Tocopherol</p> Signup and view all the answers

    What is the primary dietary source of Vitamin K1?

    <p>Leafy green vegetables</p> Signup and view all the answers

    Which of the following is NOT a function of Vitamin E?

    <p>Promotion of blood clotting</p> Signup and view all the answers

    What factor can lead to a deficiency of Vitamin K?

    <p>Malabsorption syndromes</p> Signup and view all the answers

    Which is true regarding the active forms of Vitamin A?

    <p>Retinol, retinal, and retinoic acid are active forms</p> Signup and view all the answers

    What role do rods play in vision?

    <p>They are responsible for vision in dim light</p> Signup and view all the answers

    What forms rhodopsin in the eyes?

    <p>11-trans retinal and opsin protein</p> Signup and view all the answers

    Where is vitamin D primarily stored in the body?

    <p>Liver</p> Signup and view all the answers

    What enzyme in the liver hydroxylates vitamin D3 to 25-(OH)-D3?

    <p>25-hydroxylase</p> Signup and view all the answers

    Which hormone stimulates the synthesis of calcitriol in the kidney?

    <p>Parathyroid hormone (PTH)</p> Signup and view all the answers

    What does a decrease in blood calcium levels stimulate?

    <p>Secretion of parathyroid hormone (PTH)</p> Signup and view all the answers

    Which of the following is NOT a function of active vitamin D (Calcitriol)?

    <p>Increases absorption of vitamin C in the intestine</p> Signup and view all the answers

    What condition is caused by vitamin D deficiency in young children?

    <p>Rickets</p> Signup and view all the answers

    Which of the following is a common cause of vitamin D deficiency?

    <p>Minimal exposure to sunlight</p> Signup and view all the answers

    What can lead to vitamin D toxicity?

    <p>Self-medication with vitamin D supplements</p> Signup and view all the answers

    Study Notes

    Biochemistry of Vitamins

    • Vitamins are organic compounds
    • They are essential for human health and growth
    • Vitamins are required in small amounts
    • Deficiency of a vitamin can result in a specific nutrition deficiency disease
    • Vitamins are not synthesized in the human body, must be obtained from the diet
    • Vitamins do not participate in tissue structure like carbohydrates, fats, and proteins
    • Vitamins do not yield energy, but facilitate energy-yielding chemical reactions
    • Vitamins act as coenzymes
    • Vitamins are classified based on their solubility into two main groups: fat-soluble and water-soluble
    • Fat-soluble vitamins include vitamins A (ADEK)
    • Water-soluble vitamins include the B vitamins and vitamin C

    Fat-Soluble Vitamins

    • Vitamin A (retinol, retinal, retinoic acid)
      • Active forms of vitamin A are retinol, retinal, and retinoic acid.
      • Sources: Animal sources (meat, liver, milk, butter, egg yolk, fish liver oils) as retinol esters; plant sources (carrots, sweet potatoes) as carotenoids. α, β, γ-carotenes are important carotenoids, with β-carotene having the highest activity.
      • Functions:
        • Vision (rhodopsin in rods for dim light, iodopsin in cones for bright light)
        • Supports normal growth of bones and teeth
        • Role in reproduction in males and females
        • Immunostimulant
        • Anticancer agent, due to antioxidant properties
      • Deficiency: Night blindness, xerophthalmia (cornea drying), growth retardation, increased susceptibility to cancer and anemia, rough skin (xeroderma), and mucous membrane problems of urinary, genital, gastrointestinal, and respiratory tracts leading to infections.
    • Vitamin D (cholecalciferol/ergocalciferol)
      • Sources: Provitamin 7-dehydrocholesterol in animals and man; ergosterol in plants, converted to vitamin D3 (cholecalciferol) by UV exposure and vitamin D2 (ergocalciferol) by UV exposure
      • Active form: calcitriol (1,25-dihydroxycholecalciferol) is formed in the liver and kidney by enzymatic hydroxylation
      • Functions: Essential for calcium and phosphorus absorption in the intestines and bone mineralization.
      • Deficiency: Rickets in children and osteomalacia in adults.
      • Regulation: Controlled by parathyroid hormone (PTH) and blood calcium and phosphate levels.
    • Vitamin E (tocopherols)
      • Sources: Vegetable oils (wheat germ, cottonseed, olive, coconut), liver, egg yolk, milk, colostrum,
      • Functions: Antioxidant, prevents hemolytic anemia, important for pregnancy in animals
    • Vitamin K (phylloquinone/menaquinone)
      • Sources: Plants (spinach, cauliflower, cabbage) as phylloquinone; bacteria in the intestines as menaquinone
      • Functions: Antihemorrhagic (essential for blood clotting), activates osteocalcin in bone.

    Water-Soluble Vitamins

    • Information on Water-Soluble Vitamins not included in the provided text.

    Vitamin Toxicity

    • Vitamin D toxicity (Hypervitaminosis): Usually occurs due to self-medication. Results in hypercalcemia, leading to abnormal calcification in soft tissues (like kidney) and blood vessels, and potentially hypertension

    Additional Note

    • The provided text included multiple questions. Those questions are not included in the summary as the summary focused on the main topics.

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    Description

    Explore the essential role of vitamins in human health and growth through this quiz. Learn about their classifications, sources, functions, and the consequences of deficiencies. Discover the distinction between fat-soluble and water-soluble vitamins.

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