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Questions and Answers
What is the main difference between isoenzymes?
What is the main difference between isoenzymes?
- They are found in different locations in the body. (correct)
- They catalyze different reactions.
- They are made of completely different amino acids.
- They have different active sites.
Which of the following isoenzymes is found predominantly in the liver or skeletal tissues?
Which of the following isoenzymes is found predominantly in the liver or skeletal tissues?
- LDH5 (correct)
- LDH3
- LDH2
- LDH1
How many subunits does the Lactate dehydrogenase (LDH) enzyme have?
How many subunits does the Lactate dehydrogenase (LDH) enzyme have?
- 3
- 4 (correct)
- 2
- 1
What is the primary function of enzymes?
What is the primary function of enzymes?
Which isoenzyme of Creatine phosphokinase (CPK) is primarily found in the brain?
Which isoenzyme of Creatine phosphokinase (CPK) is primarily found in the brain?
Flashcards
Enzymes
Enzymes
Biological catalysts that speed up chemical reactions in the body.
Isoenzymes
Isoenzymes
Enzymes that catalyze the same reaction but differ in structure or composition.
Lactate Dehydrogenase (LDH)
Lactate Dehydrogenase (LDH)
A tetrameric enzyme with 5 forms, each found in different body tissues.
Creatine Phosphokinase (CPK)
Creatine Phosphokinase (CPK)
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Enzyme function in diagnosis
Enzyme function in diagnosis
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Study Notes
Enzymes in the Body
- Enzymes are biological catalysts that accelerate chemical reactions in the body.
- Isoenzymes catalyze the same reaction but have different structures/subunit compositions.
- Enzymes are used in diagnostic medicine.
Lactate Dehydrogenase (LDH)
- LDH is a tetrameric enzyme with 2 subunits.
- It exists in 5 forms (isoenzymes).
- LDH 1 is found in cardiac cells.
- LDH 2 is found in red blood cells.
- LDH 3 is found in the lungs.
- LDH 4 is found in the kidney/pancreatic cells.
- LDH 5 is found in the liver/skeletal tissues.
Creatine Phosphokinase (CPK)
- CPK is a dimeric enzyme with protomers.
- It exists in 3 forms (isoenzymes).
- BB form is in the brain.
- MM form is in muscle.
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