Bioavailability of Amoxicillin Quiz

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Questions and Answers

What does the term 'efficacy' refer to in pharmacology?

  • The selectivity of a drug towards a particular receptor
  • The greatest maximal response that can be produced from a particular drug (correct)
  • The process by which a drug is eliminated from the body
  • The dose at which a drug produces its therapeutic effect

Which of the following statements falls under the category of pharmacokinetics?

  • The half-life of a drug (correct)
  • Pharmacodynamics
  • The selectivity of a drug towards a receptor
  • Drug indication

What does a high therapeutic index (TI) indicate about a drug?

  • The drug is toxic
  • The drug is not effective
  • The drug is potent
  • The drug is safe (correct)

If a drug is known to be selective to receptor (A), what does this imply?

<p>Drug (a) cannot bind to receptor (B) (C)</p> Signup and view all the answers

What is the main purpose of therapeutic drug monitoring?

<p>To confirm the therapeutic dose of a drug (D)</p> Signup and view all the answers

How is half-life defined in pharmacokinetics?

<p>The time required for a drug's plasma concentration to decrease by half after administration (C)</p> Signup and view all the answers

How does drug-protein binding affect pharmacological activity?

<p>Drugs bound to plasma proteins are inactive and do not produce any effect (D)</p> Signup and view all the answers

What does a higher volume of distribution (Vd) indicate about a drug?

<p>The drug is distributed throughout the body in higher amounts (A)</p> Signup and view all the answers

What does drug elimination primarily refer to?

<p>1 and 2 (D)</p> Signup and view all the answers

What is the main goal when administering a drug on multiple doses over an extended period?

<p>To ensure drug plasma level remains within the therapeutic range (A)</p> Signup and view all the answers

Which term is used to describe the dose required to produce a specific therapeutic response in 50% of a group of patients?

<p>Median effective dose (ED50) (B)</p> Signup and view all the answers

What does the Therapeutic Index (TI) describe?

<p>The ratio of LD50 to ED50 (A)</p> Signup and view all the answers

What is the significance of a large Therapeutic Index (TI) value for a drug?

<p>It signifies that the drug is relatively safe (C)</p> Signup and view all the answers

Which aspect of pharmacokinetics does not involve drug-receptor binding?

<p>Elimination (D)</p> Signup and view all the answers

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