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Questions and Answers
In single-dose bioavailability studies, the sampling time for blood and/or urine is usually at least how many times the half-life of the active drug ingredient or therapeutic moiety?
In single-dose bioavailability studies, the sampling time for blood and/or urine is usually at least how many times the half-life of the active drug ingredient or therapeutic moiety?
- Two times
- Three times (correct)
- Ten times
- Five times
In multiple-dose bioavailability studies, what is compared to determine steady-state levels of the active drug ingredient or therapeutic moiety?
In multiple-dose bioavailability studies, what is compared to determine steady-state levels of the active drug ingredient or therapeutic moiety?
- Rate of absorption
- Elimination half-life
- Volume of distribution
- Test product and the reference material (correct)
What is measured in single-dose bioavailability studies?
What is measured in single-dose bioavailability studies?
- Elimination half-life only
- Time taken to reach peak concentration
- Volume of distribution
- Peak concentration in the blood and the total area under the curve (correct)
In single-dose bioavailability studies, what type of design is usually used?
In single-dose bioavailability studies, what type of design is usually used?
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What is the fasting state in which single-dose bioavailability studies are conducted?
What is the fasting state in which single-dose bioavailability studies are conducted?
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