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Questions and Answers
What is the purpose of a dosage regimen?
What is the purpose of a dosage regimen?
- To decrease the maintenance dose in liver or renal disease
- To increase the risk of drug toxicity
- To quickly achieve the volume of distribution
- To maintain plasma concentration within therapeutic levels (correct)
What is the formula for the maintenance dose?
What is the formula for the maintenance dose?
- Cp x Dose interval
- Cp x Vd x F
- Cp x Cl x Dose interval (correct)
- Cp x Cl
What does the loading dose aim to achieve?
What does the loading dose aim to achieve?
- Increase the risk of drug toxicity
- Decrease the maintenance dose in liver or renal disease
- Quickly achieve the volume of distribution and desired plasma level (correct)
- Maintain plasma concentration within therapeutic levels
What is the purpose of reaching steady state in pharmacokinetics?
What is the purpose of reaching steady state in pharmacokinetics?
What is the disadvantage of loading doses if excess levels occur?
What is the disadvantage of loading doses if excess levels occur?
What determines the time needed to reach steady state in pharmacokinetics?
What determines the time needed to reach steady state in pharmacokinetics?
What is the primary purpose of a maintenance dose in pharmacology?
What is the primary purpose of a maintenance dose in pharmacology?
In what conditions would the maintenance dose be decreased?
In what conditions would the maintenance dose be decreased?
'Steady state' in pharmacokinetics is reached in how many half-lives?
'Steady state' in pharmacokinetics is reached in how many half-lives?
'Rate in=Rate out' signifies which pharmacokinetic concept?
'Rate in=Rate out' signifies which pharmacokinetic concept?
Which of the following best defines bioavailability?
Which of the following best defines bioavailability?
What factors can affect bioavailability?
What factors can affect bioavailability?
What is the formula for calculating bioavailability (F)?
What is the formula for calculating bioavailability (F)?
What is therapeutic equivalence in terms of drug effects and safety profile?
What is therapeutic equivalence in terms of drug effects and safety profile?
Which parameter is used to calculate dosage regimen related to loading dose, dosing rate, maintenance dose, and steady-state bioavailability?
Which parameter is used to calculate dosage regimen related to loading dose, dosing rate, maintenance dose, and steady-state bioavailability?
What is the bioavailability of a drug if it has an oral AUC of 20 mg.hr/ml and an intravenous AUC of 60 mg.hr/ml?
What is the bioavailability of a drug if it has an oral AUC of 20 mg.hr/ml and an intravenous AUC of 60 mg.hr/ml?
Which factor does not affect bioavailability?
Which factor does not affect bioavailability?
What pharmacokinetic parameter does bioavailability fall under?
What pharmacokinetic parameter does bioavailability fall under?
Which term describes the same effect and safety profile in the treatment of a disease/condition?
Which term describes the same effect and safety profile in the treatment of a disease/condition?
What does the term 'Therapeutic equivalence' refer to in pharmacology?
What does the term 'Therapeutic equivalence' refer to in pharmacology?
Which factor affects bioavailability based on the information provided?
Which factor affects bioavailability based on the information provided?
What is the formula for calculating bioavailability (F) based on the given example?
What is the formula for calculating bioavailability (F) based on the given example?
What is the primary purpose of a maintenance dose in pharmacology?
What is the primary purpose of a maintenance dose in pharmacology?
What does 'Rate in=Rate out' signify in pharmacokinetics?
What does 'Rate in=Rate out' signify in pharmacokinetics?
What pharmacokinetic parameter does bioavailability fall under?
What pharmacokinetic parameter does bioavailability fall under?
In what conditions would the maintenance dose be decreased according to pharmacological principles?
In what conditions would the maintenance dose be decreased according to pharmacological principles?
'Steady state' in pharmacokinetics is reached in how many half-lives?
'Steady state' in pharmacokinetics is reached in how many half-lives?
What is the disadvantage of loading doses if excess levels occur?
What is the disadvantage of loading doses if excess levels occur?
What is the formula for calculating the loading dose (Ld) in pharmacokinetics?
What is the formula for calculating the loading dose (Ld) in pharmacokinetics?
What is the disadvantage of loading doses if excess levels occur in pharmacokinetics?
What is the disadvantage of loading doses if excess levels occur in pharmacokinetics?
Which formula represents the maintenance dose (Md) in pharmacokinetics?
Which formula represents the maintenance dose (Md) in pharmacokinetics?
When reaching steady-state in pharmacokinetics, what does the rate in equal to?
When reaching steady-state in pharmacokinetics, what does the rate in equal to?
In what conditions would the maintenance dose be decreased in pharmacokinetics?
In what conditions would the maintenance dose be decreased in pharmacokinetics?
What determines the time needed to reach steady state in pharmacokinetics?
What determines the time needed to reach steady state in pharmacokinetics?
'Steady-state' in pharmacokinetics is reached in how many half-lives?
'Steady-state' in pharmacokinetics is reached in how many half-lives?
'Must have comparable efficacy and safety' refers to which concept in pharmacology?
'Must have comparable efficacy and safety' refers to which concept in pharmacology?
What is the primary purpose of a dosage regimen in pharmacokinetics?
What is the primary purpose of a dosage regimen in pharmacokinetics?
Which term describes the same effect and safety profile in the treatment of a disease/condition?
Which term describes the same effect and safety profile in the treatment of a disease/condition?
