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Questions and Answers
What are the major functions of the nervous system?
What are the major functions of the nervous system?
Which component is NOT part of the central nervous system?
Which component is NOT part of the central nervous system?
What role do sensory receptors play in the sensory system?
What role do sensory receptors play in the sensory system?
Which part of the nervous system is responsible for initiating motor activities?
Which part of the nervous system is responsible for initiating motor activities?
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What are afferent nerve fibers responsible for?
What are afferent nerve fibers responsible for?
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External receptors are primarily located on which part of the body?
External receptors are primarily located on which part of the body?
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What does the intellectual nervous system provide the basis for?
What does the intellectual nervous system provide the basis for?
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Which statement about sensory receptors is INCORRECT?
Which statement about sensory receptors is INCORRECT?
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What happens to the retinal receptors when heavy mechanical stimuli are applied to the eye?
What happens to the retinal receptors when heavy mechanical stimuli are applied to the eye?
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What is the definition of excitability in receptors?
What is the definition of excitability in receptors?
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What type of potential changes occur in the receptors upon adequate stimulation?
What type of potential changes occur in the receptors upon adequate stimulation?
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Which type of receptors show hyperpolarization upon adequate stimulation?
Which type of receptors show hyperpolarization upon adequate stimulation?
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Why are Pacinian corpuscles preferred for studying receptor potential?
Why are Pacinian corpuscles preferred for studying receptor potential?
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What changes occur in the nerve terminal of Pacinian corpuscles when pressure is applied?
What changes occur in the nerve terminal of Pacinian corpuscles when pressure is applied?
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What defines phasic receptors?
What defines phasic receptors?
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What is the maximal amplitude of receptor potential that can be achieved in these receptors?
What is the maximal amplitude of receptor potential that can be achieved in these receptors?
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What is found inside the capsule of a Pacinian corpuscle?
What is found inside the capsule of a Pacinian corpuscle?
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What does modality discrimination refer to?
What does modality discrimination refer to?
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According to Muller's law, what happens when a specific receptor is stimulated?
According to Muller's law, what happens when a specific receptor is stimulated?
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What principle extends Muller's law to explain the specific pathways for each sensation?
What principle extends Muller's law to explain the specific pathways for each sensation?
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Why do tonic receptors send continuous impulses to the CNS?
Why do tonic receptors send continuous impulses to the CNS?
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How does the central mechanism of modality discrimination function?
How does the central mechanism of modality discrimination function?
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What primarily distinguishes the function of tonic receptors from phasic receptors?
What primarily distinguishes the function of tonic receptors from phasic receptors?
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What role does labelled line principle play in sensory processing?
What role does labelled line principle play in sensory processing?
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Which type of receptor is specifically stimulated by mechanical forms of energy?
Which type of receptor is specifically stimulated by mechanical forms of energy?
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What unique characteristic do receptors exhibit according to Muller's law?
What unique characteristic do receptors exhibit according to Muller's law?
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Which of the following receptors responds to temperature changes?
Which of the following receptors responds to temperature changes?
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Which type of receptor is responsible for detecting light waves?
Which type of receptor is responsible for detecting light waves?
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What type of receptors are baroreceptors, and where are they found?
What type of receptors are baroreceptors, and where are they found?
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What do nociceptors specifically respond to?
What do nociceptors specifically respond to?
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Which type of receptor is involved in detecting changes in blood pressure?
Which type of receptor is involved in detecting changes in blood pressure?
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Which receptors are triggered by chemical stimuli in the carotid bodies?
Which receptors are triggered by chemical stimuli in the carotid bodies?
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What is the primary factor in intensity discrimination related to peripheral mechanisms?
What is the primary factor in intensity discrimination related to peripheral mechanisms?
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How does the central mechanism affect intensity discrimination?
How does the central mechanism affect intensity discrimination?
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What principle explains the sensation being referred to its original site in the body?
What principle explains the sensation being referred to its original site in the body?
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What phenomenon occurs in amputees where they feel pain in a non-existing limb?
What phenomenon occurs in amputees where they feel pain in a non-existing limb?
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What type of receptors are pain receptors classified as?
What type of receptors are pain receptors classified as?
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Which type of pain receptor responds only to mechanical trauma?
Which type of pain receptor responds only to mechanical trauma?
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What type of pain receptor responds to tissue damage from chemical agents?
What type of pain receptor responds to tissue damage from chemical agents?
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At what temperature do thermal pain receptors become activated?
At what temperature do thermal pain receptors become activated?
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Study Notes
Nervous System Overview
- The nervous system is responsible for detecting, analyzing, and transmitting information.
- It's divided into the central nervous system (CNS) and the peripheral nervous system.
- The CNS includes the brain and spinal cord.
- The peripheral nervous system includes 12 pairs of cranial nerves and 31 pairs of spinal nerves.
Sensory System Overview
- The sensory nervous system detects internal and external changes and informs the CNS.
- It consists of sensory receptors, afferent nerve fibers, and sensory centers in the brain and spinal cord.
Sensory Receptors
- Sensory receptors are specialized structures located at the peripheral terminations of afferent nerves.
- They detect stimuli and convert them into nerve impulses.
- Receptors are classified based on location (external or internal) and the nature of the stimulus they detect.
External Receptors
- Located on the body surface, primarily in the skin.
- Respond to stimuli from the external environment.
Internal Receptors
- Found in deeper structures and viscera.
- Respond to changes within the body.
Receptor Classification by Stimuli
- Mechanoreceptors: Respond to mechanical stimuli (touch, pressure, vibration, sound, stretch).
- Chemoreceptors: Respond to chemical stimuli (taste, smell, blood gases).
- Thermoreceptors: Respond to changes in temperature (cold and warm).
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Pain receptors (nociceptors): Respond to injurious stimuli.
- Can be further classified into:
- Mechanical: Respond to mechanical trauma.
- Chemical: Respond to chemical agents.
- Thermal: Respond to extreme temperatures.
- Can be further classified into:
- Photoreceptors: Respond to electromagnetic waves of light.
Receptor Properties
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Specificity: Receptors are highly sensitive to a specific type of stimuli called the adequate stimulus.
- This principle is known as Muller's law.
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Excitability: Receptors respond to their adequate stimuli.
- Usually, this response involves depolarization through increased membrane permeability to sodium ions (Na+).
- Visual receptors (rods and cones) show hyperpolarization upon stimulation.
- The potential changes that occur in receptors during stimulation are called receptor potentials.
- Rate of Discharge: The frequency of nerve impulses generated by a receptor is proportional to the intensity of the stimulus.
- Adaptation: Receptors can become less responsive to a constant stimulus over time.
Intensity Discrimination
- The CNS determines stimulus intensity based on:
- Rate of impulse discharge: A higher rate indicates a stronger stimulus.
- Number of receptors activated: More receptors activated means a stronger stimulus.
Locality Discrimination
- The CNS identifies the location of a stimulus through:
- Somatotopic map: Each area of the body is represented in a specific area of the cerebral cortex with dedicated neural pathways.
- Law of projection: Although the sensory impulse arrives at the cerebral cortex, the sensation is perceived as originating from the site of stimulation in the body.
- Phantom limb phenomenon: A severe pain is felt in a missing limb.
- Phantom sensations: May occur after removal of other body parts (e.g., breast, teeth, eye).
Pain Sensation
- Pain is an unpleasant sensory and emotional experience associated with actual tissue damage.
- Pain receptors (nociceptors) are free nerve endings.
- They are specific to tissue damage, with subtypes that respond to different types of injuries (mechanical, chemical, thermal).
Coding of Sensory Information
- The CNS analyzes sensory information to determine:
- Modality (type): Each type of sensory receptor is associated with a unique sensory modality (e.g., touch, pain, sight)
- Intensity: Determined by the rate of impulse discharge and the number of receptors activated.
- Locality: The location of the stimulus is identified based on the specific pathway it travels through.
- Muller's law: Explains the principle of modality discrimination – a specific receptor type always produces the same sensory modality.
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Labelled line principle: Each sensory modality has a dedicated anatomical pathway for transmitting information to the brain.
- This ensures that the correct type of sensation is perceived.
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