BBT 302: Molecules of Life - Vitamins
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Questions and Answers

What is the recommended dietary allowance (RDA) of Vitamin K for adults?

  • 25 IU for women and 30 IU for men
  • 30 IU for both men and women
  • There are no established requirements (correct)
  • 30 IU for men and 25 IU for women
  • Which of the following statements about Vitamin K deficiency is accurate?

  • It may lead to hemorrhage in infants due to the lack of clotting factors. (correct)
  • It is rarely observed in infants due to maternal nutrition.
  • It is commonly found among adults in developed countries.
  • It can cause excessive blood clotting in infants.
  • What are the main dietary sources of Vitamin K1?

  • Grains and cereals
  • Green vegetables like spinach and cabbage (correct)
  • Dairy products and meats
  • Fruits and nuts
  • What distinguishes Vitamin K1 from Vitamin K2 structurally?

    <p>Vitamin K1 contains fewer isoprene units than Vitamin K2.</p> Signup and view all the answers

    Why was Vitamin K initially identified and named?

    <p>Because of its role in blood coagulation, observed in chicks.</p> Signup and view all the answers

    What was the original designation of Vitamin E when it was first discovered?

    <p>Anti sterility factor</p> Signup and view all the answers

    Which form of tocopherol is considered the most potent with maximum Vitamin E activity?

    <p>Alpha-tocopherol</p> Signup and view all the answers

    What major role does Vitamin E play in the human body?

    <p>Preventing oxidation of substances</p> Signup and view all the answers

    Which food sources are known to be high in Vitamin E?

    <p>Cottonseed oil and peanut oil</p> Signup and view all the answers

    How does a deficiency in Vitamin E affect fertility in animals?

    <p>Causes formation of non-motile sperms</p> Signup and view all the answers

    Which of the following statements about Vitamin E is false?

    <p>It primarily aids in nutrient absorption.</p> Signup and view all the answers

    What structural feature differentiates various tocopherols?

    <p>Substituents on carbon 5, 7, and 8</p> Signup and view all the answers

    What is the typical human requirement for Vitamin E, according to the content?

    <p>Rarely requires supplementation</p> Signup and view all the answers

    Study Notes

    Vitamins Overview

    • Vitamins are essential nutrients that play crucial roles in biological functions.
    • Fat-soluble vitamins include Vitamin E and Vitamin K, both vital for various physiological processes.

    Vitamin E

    • Discovered in vegetable oils and known as the anti-sterility factor due to its link to reproductive health.
    • Isolated from wheat germ oil and termed tocopherol; found in corn oil, rice oil, cottonseed oil, soybean, and peanuts, but not in fish liver or olive oil.
    • Comprised of tocopherols, derived from 6-hydroxychroman with an isoprenoid side chain.
    • α-tocopherol is the most biologically active form, containing three methyl groups at different carbon positions.

    Role of Vitamin E

    • Functions as an antioxidant, preventing the oxidation of substances and food spoilage.
    • Essential for reproduction, positively affecting ectoderm and endoderm (Vitamin A) and mesoderm (Vitamin E) during embryonic development.
    • Protects vitamin A from degradation and supports mitochondrial integrity by preserving unsaturated fatty acids in membranes.

    Vitamin E Deficiency

    • Can lead to sterility, embryo re-absorption, degeneration of testicular germinal epithelium, and production of non-motile sperm.
    • Recommended Dietary Allowance (RDA) for Vitamin E:
      • Men: 30 IU
      • Women: 25 IU
      • Pregnant and lactating women: 30 IU
      • Infants: 1 to 2.5 IU
    • Conversion: 1 IU is equivalent to 1.1 mg of pure compound.

    Vitamin K

    • Identified when newborn chicks fed artificial diets suffered from fatal hemorrhage due to prolonged blood clotting times.
    • Designated as Vitamin K for its role in coagulation and also known as the anti-hemorrhagic factor.
    • Exists in two forms: Vitamin K1 (found in green vegetables like spinach and cabbage) and Vitamin K2 (found in fermented fish meal and produced by intestinal bacteria).
    • Vitamin K1 is more potent compared to K2.

    Role of Vitamin K

    • Vital for synthesizing prothrombin, a blood-clotting factor essential for converting fibrinogen to fibrin during clot formation.
    • Deficiency in infants results in severe bleeding risks due to the lack of blood clotting capabilities before developing Vitamin K-producing intestinal flora.
    • Administration of Vitamin K to pregnant mothers can prevent deficiency in newborns.

    Vitamin K Deficiency

    • Occurs rarely in adults but can lead to significant bleeding complications in infants.
    • There is currently no standardized requirement for Vitamin K consumption established for humans.

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    Vitamins Lecture Notes PDF

    Description

    Explore the fascinating world of vitamins in this quiz on nucleic acids and their biological roles, focusing particularly on fat-soluble vitamins like Vitamin E. Learn about their sources, recommended dietary allowances (RDA), and impacts on sterility in animals. Test your understanding of how vitamins are essential to our health.

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