Podcast
Questions and Answers
Why is it necessary to know both the RER and the amount of oxygen consumed to accurately estimate energy expenditure?
Why is it necessary to know both the RER and the amount of oxygen consumed to accurately estimate energy expenditure?
- Because the caloric equivalent for oxygen is constant regardless of the nutrient oxidized.
- Because oxygen consumption alone determines energy expenditure.
- Because the RER only accounts for carbohydrate and protein oxidation.
- Because the caloric equivalent for oxygen varies depending on the nutrient being oxidized. (correct)
Assuming protein contribution is negligible, what does an RER of 0.85 indicate about the fuel being used for energy production?
Assuming protein contribution is negligible, what does an RER of 0.85 indicate about the fuel being used for energy production?
- Primarily carbohydrate is being utilized.
- An equal mix of carbohydrate, fat, and protein is being utilized.
- Primarily fat is being utilized.
- A mix of carbohydrate and fat is being oxidized. (correct)
Why is the protein contribution usually excluded from RER calculations in typical exercise physiology settings?
Why is the protein contribution usually excluded from RER calculations in typical exercise physiology settings?
- Protein oxidation does not produce CO~2~.
- Measuring protein oxidation requires complex urine analysis and its energy contribution is relatively small. (correct)
- The RER for protein is equal to 1.0.
- Protein's contribution to energy production is high.
If a person with a mixed carbohydrate and fat diet has an RER of 0.85, approximately how many kilocalories are produced for every liter of oxygen consumed?
If a person with a mixed carbohydrate and fat diet has an RER of 0.85, approximately how many kilocalories are produced for every liter of oxygen consumed?
A researcher measures a subject's oxygen consumption and RER during a resting metabolic rate (RMR) test. Why is it essential to have both values for each minute of the measurement?
A researcher measures a subject's oxygen consumption and RER during a resting metabolic rate (RMR) test. Why is it essential to have both values for each minute of the measurement?
An individual with a desk job who engages in light exercise twice a week wants to estimate their Total Daily Energy Expenditure (TDEE). Which activity factor (AF) from the provided chart should they use to multiply their Resting Metabolic Rate (RMR)?
An individual with a desk job who engages in light exercise twice a week wants to estimate their Total Daily Energy Expenditure (TDEE). Which activity factor (AF) from the provided chart should they use to multiply their Resting Metabolic Rate (RMR)?
A construction worker engages in heavy lifting and physical labor daily, and also participates in hard sports 6 days a week. Which activity factor should they use to estimate their TDEE?
A construction worker engages in heavy lifting and physical labor daily, and also participates in hard sports 6 days a week. Which activity factor should they use to estimate their TDEE?
A 30-year-old woman who is 165 cm tall and weighs 68 kg leads a moderately active lifestyle. Using the Harris-Benedict equation, which calculation is needed to determine her RMR?
A 30-year-old woman who is 165 cm tall and weighs 68 kg leads a moderately active lifestyle. Using the Harris-Benedict equation, which calculation is needed to determine her RMR?
If an individual calculates their TDEE to be 2500 kcal to maintain their current weight, what adjustments should they make to their daily caloric intake to lose weight?
If an individual calculates their TDEE to be 2500 kcal to maintain their current weight, what adjustments should they make to their daily caloric intake to lose weight?
A moderately active 45-year-old male, standing 180 cm tall and weighing 85 kg, uses the Harris-Benedict equation to estimate his RMR. To determine his TDEE for weight maintenance, what additional step must he take after calculating his RMR?
A moderately active 45-year-old male, standing 180 cm tall and weighing 85 kg, uses the Harris-Benedict equation to estimate his RMR. To determine his TDEE for weight maintenance, what additional step must he take after calculating his RMR?
What are the three critical components directly measured by metabolic carts?
What are the three critical components directly measured by metabolic carts?
Why is it important to measure local barometric pressure and ambient temperature when using a metabolic cart?
Why is it important to measure local barometric pressure and ambient temperature when using a metabolic cart?
For best results, how often should data be averaged when using a metabolic cart?
For best results, how often should data be averaged when using a metabolic cart?
Which of the following is a primary reason for using RMR prediction equations instead of direct assessment?
Which of the following is a primary reason for using RMR prediction equations instead of direct assessment?
What is the most important factor in determining the validity of an RMR prediction equation?
What is the most important factor in determining the validity of an RMR prediction equation?
Which type of equation will outperform a body composition-based equation if used in the right population?
Which type of equation will outperform a body composition-based equation if used in the right population?
What is the purpose of applying an activity factor (AF) after estimating RMR?
What is the purpose of applying an activity factor (AF) after estimating RMR?
How should an individual's activity level be considered when applying an activity factor (AF)?
How should an individual's activity level be considered when applying an activity factor (AF)?
A researcher is studying energy expenditure in a group of generally active individuals. Which equation, incorporating body mass (BM), height (H), and age, is most appropriate according to the content provided?
A researcher is studying energy expenditure in a group of generally active individuals. Which equation, incorporating body mass (BM), height (H), and age, is most appropriate according to the content provided?
Which of the following best describes the relationship between Basal Metabolic Rate (BMR) and Resting Metabolic Rate (RMR)?
Which of the following best describes the relationship between Basal Metabolic Rate (BMR) and Resting Metabolic Rate (RMR)?
A researcher is preparing to measure a subject's RMR. Which of the following pre-test conditions is NOT required, according to the guidelines?
A researcher is preparing to measure a subject's RMR. Which of the following pre-test conditions is NOT required, according to the guidelines?
How would you modify the Mifflin-St. Jeor equation for a female subject when calculating resting energy expenditure?
How would you modify the Mifflin-St. Jeor equation for a female subject when calculating resting energy expenditure?
Indirect calorimetry estimates RMR by measuring:
Indirect calorimetry estimates RMR by measuring:
Why is the respiratory exchange ratio (RER) useful in metabolic studies?
Why is the respiratory exchange ratio (RER) useful in metabolic studies?
Under what condition are the respiratory quotient (RQ) and respiratory exchange ratio (RER) expected to be most similar?
Under what condition are the respiratory quotient (RQ) and respiratory exchange ratio (RER) expected to be most similar?
Using the Weir equation, which variable has the greatest impact on RMR?
Using the Weir equation, which variable has the greatest impact on RMR?
A subject's expired breath is analyzed, and it's found that the concentration of oxygen has decreased compared to atmospheric air. What does this indicate?
A subject's expired breath is analyzed, and it's found that the concentration of oxygen has decreased compared to atmospheric air. What does this indicate?
Which equation is designed specifically for calculating resting metabolic rate in subjects with obesity?
Which equation is designed specifically for calculating resting metabolic rate in subjects with obesity?
What is the significance of using Fat-Free Mass (FFM) in predictive equations for resting metabolic rate?
What is the significance of using Fat-Free Mass (FFM) in predictive equations for resting metabolic rate?
Why is it important to conduct RMR assessments in a dark room with no distractions?
Why is it important to conduct RMR assessments in a dark room with no distractions?
According to the provided text, which component makes up the smallest percentage of TDEE?
According to the provided text, which component makes up the smallest percentage of TDEE?
If a person's RER is consistently around 0.7, what does this suggest about their primary fuel source?
If a person's RER is consistently around 0.7, what does this suggest about their primary fuel source?
A researcher measures VO2 at 2 L/min and VCO2 at 1.6 L/min. What is the RER, and what does it suggest about the fuel utilization?
A researcher measures VO2 at 2 L/min and VCO2 at 1.6 L/min. What is the RER, and what does it suggest about the fuel utilization?
A researcher finds it difficult for subjects to adhere to overnight stays in the metabolic lab when measuring BMR. What is a more practical alternative mentioned in the text?
A researcher finds it difficult for subjects to adhere to overnight stays in the metabolic lab when measuring BMR. What is a more practical alternative mentioned in the text?
Flashcards
Resting Metabolic Rate (RMR)
Resting Metabolic Rate (RMR)
The energy expenditure at rest in a neutral environment.
Activity Factor (AF)
Activity Factor (AF)
A numerical factor representing a person's typical daily activity level.
TDEE
TDEE
Total Daily Energy Expenditure: estimate of calories burned in a day.
Sedentary Activity Factor
Sedentary Activity Factor
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Extremely Active Factor
Extremely Active Factor
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Respiratory Exchange Ratio (RER)
Respiratory Exchange Ratio (RER)
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RER for Carbohydrate
RER for Carbohydrate
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RER for Fat
RER for Fat
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Typical Resting RER
Typical Resting RER
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Kcal per Liter O2 (RER = 0.85)
Kcal per Liter O2 (RER = 0.85)
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Metabolic Cart
Metabolic Cart
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Barometric Pressure & Ambient Temperature
Barometric Pressure & Ambient Temperature
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Mixing Chamber
Mixing Chamber
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RMR Prediction Equations
RMR Prediction Equations
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Population (for RMR equations)
Population (for RMR equations)
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Average Activity Level
Average Activity Level
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RMR
RMR
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Mifflin-St Jeor Equation
Mifflin-St Jeor Equation
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VO2
VO2
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VCO2
VCO2
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Respiratory Quotient (RQ)
Respiratory Quotient (RQ)
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VCO2/VO2 Ratio
VCO2/VO2 Ratio
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RQ/RER Formula
RQ/RER Formula
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FFM
FFM
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Basal Metabolic Rate (BMR)
Basal Metabolic Rate (BMR)
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Total Daily Energy Expenditure (TDEE)
Total Daily Energy Expenditure (TDEE)
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Activity Thermogenesis (AT)
Activity Thermogenesis (AT)
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Exercise Activity Thermogenesis (EAT)
Exercise Activity Thermogenesis (EAT)
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Nonexercise Activity Thermogenesis (NEAT)
Nonexercise Activity Thermogenesis (NEAT)
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Indirect Calorimetry
Indirect Calorimetry
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Weir Equation for RMR
Weir Equation for RMR
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Study Notes
- Basal metabolic rate (BMR) is the minimum energy needed to sustain vital functions while awake, measured in kcal/day.
- BMR constitutes the largest portion of total daily energy expenditure (TDEE).
- TDEE comprises BMR (60-75%), the thermic effect of feeding (TEF, 10%), and activity thermogenesis (AT, 15-30%).
- Activity thermogenesis includes exercise activity thermogenesis (EAT) and nonexercise activity thermogenesis (NEAT).
- True BMR requires overnight stays in a metabolic lab due to strict sleep and fasting requirements.
- Resting metabolic rate (RMR) is measured instead, requiring resting and fasting, but not overnight stays.
Guidelines for RMR Assessment
- Fast from all calorie-containing food and beverages for at least 8 hours.
- Rest in a dark, distraction-free room for 30 minutes before the test.
- Abstain from exercise for at least 24 hours.
- Avoid caffeine or other stimulants for at least 12 hours prior to the test.
- RMR can be assessed anytime if the above conditions are met, but mornings are preferred for comfort and overnight fasting.
- RMR assessed via indirect calorimetry, using metabolic carts to measure carbon dioxide (VCO2) production and oxygen (VO2) consumption.
- Atmospheric composition: 20.93% oxygen, 0.03% carbon dioxide, 79.04% nitrogen.
- Expired breath differs as oxygen decreases, carbon dioxide increases, but nitrogen remains unchanged.
Weir Equation for Estimating RMR
- RMR = 1.44 × [(VO2 × 3.9) + (VCO2 × 1.1)]
- Oxygen consumption and carbon dioxide production reflect the fractions of these gases in air and expired breath, as well as air volume per breath.
- Metabolic carts measure percentages of oxygen and carbon dioxide in expired breath and breath volume.
- Gas volume is affected by temperature and pressure, making local barometric pressure and ambient temperature important measurements.
- Some metabolic carts measure expired gases, ventilation, temperature, and pressure per breath; others use a mixing chamber for averages.
- One-minute averages are recommended for best data.
Estimating Resting Metabolic Rate
- Directly assessing RMR can be difficult, costly (>$60,000), and require trained technicians.
- Prediction equations are commonly used in field settings.
- Prediction equations use metrics like height, weight, body composition, age, and sex.
- Equation validity depends on the population it was developed for.
- Body weight-based equations can outperform body composition-based ones if used in the correct population.
- RMR is converted to TDEE using an activity factor (AF).
- AF estimates a person's average daily activity level
- Sedentary (desk job, little exercise): multiply by 1.2
- Lightly Active (light exercise/sports 1–3 days/week): multiply by 1.375
- Moderately Active (moderate exercise/sports 3–5 days/week): multiply by 1.55
- Very Active (hard exercise/sports 6–7 days/week): multiply by 1.725
- Extremely Active (hard daily exercise/sports and physical job or training): multiply by 1.9
- TDEE = RMR × AF estimates the kilocalories needed to maintain weight.
- Consume below this number for weight loss and above it for weight gain.
Respiratory Exchange Ratio and Respiratory Quotient
- Respiratory quotient (RQ) or respiratory exchange ratio (RER) indicates the type of fuel being used.
- RQ and RER differ only in measurement location: cellular level and expired gases, respectively; this lab refers to RER.
- RER is calculated as VCO2 / VO2
- Ratios measure carbon dioxide produced relative to oxygen consumed.
- Carbohydrate, fat, and protein require different oxygen amounts for oxidation.
- Caloric equivalent for oxygen varies depending on the nutrient oxidized, requiring RER knowledge.
- Kilocalories produced per liter of oxygen consumed depend on the utilized substrate or RER.
- RER values: 1.0 for carbohydrate, 0.70 for fat, 0.82 for protein.
- Protein contribution to energy production is low (generally less than 5%).
- RER is generally considered to be nonprotein RER due to the complexity of analysis
- Kilocalories produced per liter of oxygen consumed depends on whether fuel mix of carbohydrate and fat .
- RER value of 0.85 at rest with a mixed diet is about 4.86 kcal produced per 1 L of oxygen consumed.
- Researchers must measure oxygen consumption and RER value to determine kilocalories produced per minute.
- Carbohydrate's RER is 1.0, while fat's RER is 0.7
- Carb oxidation: C6H12O6+6 O2 → 6 CO2 + 6 H2O + 38 АТР
- Fat Oxidation: C16H32O2 + 23 O2 → 16 CO2 + 16 H2O + 129 АТР
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Description
Explore basal metabolic rate (BMR) and resting metabolic rate (RMR), key components of total daily energy expenditure (TDEE). Understand the guidelines for accurate RMR assessment, including fasting and rest requirements. Learn how these measurements differ and their significance in energy expenditure.