Bacterial Mechanisms of Evading Immune Responses
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Questions and Answers

Which mechanism allows Listeria monocytogenes and Shigella to survive within the phagolysosome?

  • Preventing fusion of phagosomes with lysosomes (correct)
  • Producing capsules that resemble host tissue components
  • Producing IgA proteases that destroy secretory IgA
  • Making antigenic variations in pili
  • How do some bacteria like S.pyogenes evade the specific immune response?

  • By preventing fusion of phagosomes with lysosomes
  • By making antigenic variations in pili
  • By producing capsules that resemble host tissue components (correct)
  • By producing IgA proteases that destroy secretory IgA
  • Which enzyme catalyzes the formation of a blood clot, protecting bacteria from phagocytosis?

  • Coagulase (correct)
  • Streptokinase
  • Hyaluronidase
  • Hemolysins
  • What is the role of Streptokinase in bacterial infections?

    <p>Dissolves fibrin clots used by the body to restrict infection areas</p> Signup and view all the answers

    Which enzyme is known as the 'spreading factor' and digests hyaluronic acid?

    <p>Hyaluronidase</p> Signup and view all the answers

    How do hemolysins contribute to bacterial virulence?

    <p>Cause lysis of erythrocytes</p> Signup and view all the answers

    Which type of bacterial toxin is composed of lipopolysaccharide (LPS) and is part of the outer membrane of gram-negative bacteria cell walls?

    <p>Endotoxin</p> Signup and view all the answers

    What type of toxin is secreted by living bacterial cells into the infected tissue, showing strong specificity for a target cell?

    <p>Exotoxin</p> Signup and view all the answers

    Which category of exotoxins adversely impacts the nervous system, leading to symptoms such as paralysis?

    <p>Neurotoxins</p> Signup and view all the answers

    What are the earliest symptoms of disease caused by the activation of the body defenses?

    <p>Pain, soreness, swelling</p> Signup and view all the answers

    Which factor greatly influences the dissemination of infection by determining how pathogens depart from the body?

    <p>Portals of exit</p> Signup and view all the answers

    Exotoxins can be categorized based on their impact on different tissues; which category damages various cell types?

    <p>Cytotoxins</p> Signup and view all the answers

    Which attribute of antibiotics refers to their ability to kill or inhibit the growth of bacteria without harming the host?

    <p>Selective toxicity</p> Signup and view all the answers

    How do most commonly used antibiotics exert their effect?

    <p>Interference with protein synthesis</p> Signup and view all the answers

    Which classification of antimicrobial agents distinguishes between narrow-spectrum and broad-spectrum drugs?

    <p>Antimicrobial spectrum</p> Signup and view all the answers

    What is the estimated percentage of human pathogens that have zoonotic origins?

    <p>70%</p> Signup and view all the answers

    Which disease is caused by Bacillus anthracis and is considered a zoonotic infection?

    <p>Anthrax</p> Signup and view all the answers

    What is the primary mode of action for antibiotics that disrupt cell membranes?

    <p>Directly destroying the cell wall</p> Signup and view all the answers

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