6 Questions
Which proteins are noncovalently associated with the receptors to form the B cell receptor complex?
Igα and Igβ
Which tyrosine kinases phosphorylate the ITAMs of Igα and Igβ in the B cell receptor complex?
Syk and ZAP-70
What is the result of receptor-induced signaling in B cells?
Activation of transcription factors
Which process is similar to the activation of B cells?
Activation of T cells
What is required for antigen receptor-mediated signal transduction in B cells?
Cross-linking of two or more membrane Ig molecules
Which antigens are able to bind to numerous Ig receptors on a B cell at the same time?
Polysaccharides, lipids, and other nonprotein antigens
Test your knowledge on B lymphocyte activation and antigen receptor-mediated signal transduction in B cells.
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