B Cell Activation and Signal Transduction Quiz
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Questions and Answers

Which proteins are noncovalently associated with the receptors to form the B cell receptor complex?

  • Syk and ZAP-70
  • CD3 and ζ
  • Igα and Igβ (correct)
  • ITAM and ITIM

Which tyrosine kinases phosphorylate the ITAMs of Igα and Igβ in the B cell receptor complex?

  • ITAM and ITIM
  • B cells and T cells
  • CD3 and ζ
  • Syk and ZAP-70 (correct)

What is the result of receptor-induced signaling in B cells?

  • Expression of genes involved in T cell proliferation
  • Activation of transcription factors (correct)
  • Phosphorylation of ITAMs
  • Activation of CD3 proteins

Which process is similar to the activation of B cells?

<p>Activation of T cells (D)</p> Signup and view all the answers

What is required for antigen receptor-mediated signal transduction in B cells?

<p>Cross-linking of two or more membrane Ig molecules (B)</p> Signup and view all the answers

Which antigens are able to bind to numerous Ig receptors on a B cell at the same time?

<p>Polysaccharides, lipids, and other nonprotein antigens (D)</p> Signup and view all the answers

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