Podcast
Questions and Answers
What is the primary function of the medullary thymic epithelial cells (MTECs) in the thymus?
What is the primary function of the medullary thymic epithelial cells (MTECs) in the thymus?
- To form the Hassall corpuscles in the medulla of the thymus
- To provide a rich vascular supply and efferent lymphatic vessels to the thymus
- To produce lymphocyte precursors derived from the bone marrow
- To present self-antigens to developing T cells and cause their elimination (correct)
Which of the following cell types are derived from the bone marrow and found in the thymus?
Which of the following cell types are derived from the bone marrow and found in the thymus?
- Macrophages and lymphocyte precursors (correct)
- Hassall corpuscles
- Epithelial cells
- Medullary thymic epithelial cells (MTECs)
What is the origin of the epithelial component of the thymus?
What is the origin of the epithelial component of the thymus?
- Differentiation of lymphocyte precursors derived from the bone marrow
- Transformation of Hassall corpuscles in the medulla of the thymus
- Proliferation of medullary thymic epithelial cells (MTECs)
- Invaginations of the ectoderm in the developing neck and chest of the embryo (correct)
What is the function of the Hassall corpuscles found in the medulla of the thymus?
What is the function of the Hassall corpuscles found in the medulla of the thymus?
What is the primary function of the efferent lymphatic vessels that drain the thymus?
What is the primary function of the efferent lymphatic vessels that drain the thymus?
What is the main function of Langerhans cells?
What is the main function of Langerhans cells?
Which type of cells express TLRs and other innate pattern recognition receptors?
Which type of cells express TLRs and other innate pattern recognition receptors?
Where do epidermal Langerhans cells and dermal dendritic cells present peptide-MHC complexes?
Where do epidermal Langerhans cells and dermal dendritic cells present peptide-MHC complexes?
Which cells are activated by cytokines secreted by keratinocytes and sentinel cells?
Which cells are activated by cytokines secreted by keratinocytes and sentinel cells?
What is the function of fibroblasts in the immune response?
What is the function of fibroblasts in the immune response?
Which cell type is known for its role in producing granulocyte-macrophage colony-stimulating factor?
Which cell type is known for its role in producing granulocyte-macrophage colony-stimulating factor?
Which statement about B cells is correct?
Which statement about B cells is correct?
Where do committed T cell precursors undergo final differentiation?
Where do committed T cell precursors undergo final differentiation?
Which cells found in the bone marrow are permanently differentiated?
Which cells found in the bone marrow are permanently differentiated?
Which cells are responsible for the development of humoral immunological memory?
Which cells are responsible for the development of humoral immunological memory?
What is the function of the thymus?
What is the function of the thymus?
Which cells in the thymus produce cytokines required for early T cell development?
Which cells in the thymus produce cytokines required for early T cell development?
