34 Questions
Where does the B cell undergo nearly all of its development?
Red bone marrow
What is the primary function of the thymus gland in the immune system?
Maturation of T cells
Which organ takes over most hematopoietic functions as development proceeds?
Bone marrow
What type of cells make up the yellow bone marrow?
Fat cells
Where is the thymus gland located in the body?
Between the sternum and the aorta
Which organ serves as a primary lymphoid organ where lymphocytes mature?
Bone marrow
Where does the immature T cell, called a thymocyte, primarily mature?
Thymus gland
Which organ is responsible for hematopoiesis and consists largely of fat cells?
Yellow bone marrow
What is the primary function of the primary lymphoid organs in the immune system?
Selection of lymphocytes
Which organ is a bilobed organ located between the sternum and the aorta of the heart?
Thymus gland
In which organ does the B cell mostly undergo its development?
Red bone marrow
Which connective tissue structure further divides the thymus into lobules?
Trabeculae
What is the main function of tonsils in the body?
To recognize and eliminate pathogens
Where is mucosa-associated lymphoid tissue (MALT) found in the body?
Underlying the mucosa of various organs
What specific role do Peyer’s patches play in the immune system?
Initiate immune responses against ingested substances
What type of cells within MALT samples material from the intestinal lumen for immune responses?
M cells
What can happen if there is a blockage of the lumen in the appendix involving MALT?
Immune response activation
Why are tonsils often removed in children with recurring throat infections?
To eliminate interference with breathing and swallowing
What is the main difference between a naïve lymphocyte and an activated lymphocyte?
Naïve lymphocytes have not yet encountered an antigen, while activated lymphocytes have.
What is the function of germinal centers in secondary lymphoid organs?
Sites of rapidly dividing and differentiating B lymphocytes
What is the role of high endothelial venules in secondary lymphoid organs?
Facilitate direct entry of cells from the blood into the tissues
What is the primary function of lymph nodes in the immune system?
Remove debris and pathogens from the lymph
Where do lymphocytes primarily develop and mature?
Primary lymphoid organs
What is a defining feature of lymphoid follicles in secondary lymphoid organs?
Sites of the formation of B and T cells
What is the primary function of dendritic cells and macrophages in the lymph node?
Internalizing and killing pathogens
Which structural feature provides support to the lymph node by laying down reticular fibers?
Fibroblasts
What is the main function of the spleen in relation to blood?
Filtering blood and removing microbes
Which statement best describes the function of red pulp in the spleen?
Acts as a filtration system for the blood using immune cells
What is the role of white pulp in the spleen?
Mounting adaptive T and B cell responses
Where are lymphoid nodules commonly found in the body?
Respiratory and digestive tracts
What is the role of tonsils in developing immunity?
Developing immunity to oral pathogens
Which type of cells are found in dense clusters within lymphoid nodules?
T cells
What is the function of medullary sinuses in the lymph node?
Collecting lymph before leaving via efferent vessels
What provides structural support to the lymph nodes along with the capsule and trabeculae?
Reticular fibers laid down by fibroblasts
Explore the differentiation and development of B and T cells, which play a crucial role in the adaptive immune response. Learn about the primary lymphoid organs, bone marrow, and thymus gland, where lymphocytes mature and proliferate to effectively target pathogens while preserving body cells. Dive into the intricacies of the adaptive immune system.
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