6 Questions
Which cells migrate toward the B cell zone and interact with antigen-stimulated B lymphocytes in peripheral lymphoid organs?
CD4+ helper T cells
What is required for the initial activation of T cells?
Antigen recognition and costimulation
What stimulates the expression of costimulators on antigen-presenting cells (APCs)?
Protein antigens administered with adjuvants
Which chemokine receptor is increased in expression by activated T cells?
CXCR5
Which cells migrate towards one another and meet at the edges of lymphoid follicles or in inter-follicular areas?
T cells and B cells
What is one mechanism for ensuring that rare antigen-specific lymphocytes can locate one another during immune responses?
Regulated migration
Test your knowledge on the activation of CD4+ helper T cells and their interaction with B lymphocytes in peripheral lymphoid organs. Explore the requirements for T cell activation and the antigens that stimulate these cells.
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