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What does ABP stand for?
What does ABP stand for?
Which of the following abbreviations represents a condition related to the prostate gland?
Which of the following abbreviations represents a condition related to the prostate gland?
What does the abbreviation DKA stand for?
What does the abbreviation DKA stand for?
Which abbreviation is associated with heart rhythm assessment?
Which abbreviation is associated with heart rhythm assessment?
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What does the abbreviation INR stand for in medical terms?
What does the abbreviation INR stand for in medical terms?
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Which abbreviation refers to a type of diabetes requiring insulin treatment?
Which abbreviation refers to a type of diabetes requiring insulin treatment?
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What does the abbreviation MRSA stand for?
What does the abbreviation MRSA stand for?
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Which abbreviation refers to a test used to assess glucose tolerance?
Which abbreviation refers to a test used to assess glucose tolerance?
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What does the abbreviation ESR stand for in medical terms?
What does the abbreviation ESR stand for in medical terms?
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What does the abbreviation OTC stand for in medical context?
What does the abbreviation OTC stand for in medical context?
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What does the abbreviation PR stand for in medical context?
What does the abbreviation PR stand for in medical context?
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What does the abbreviation CK stand for in medical terms?
What does the abbreviation CK stand for in medical terms?
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Which abbreviation represents a condition related to the kidneys?
Which abbreviation represents a condition related to the kidneys?
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What does the abbreviation ECG stand for in medical terms?
What does the abbreviation ECG stand for in medical terms?
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Which abbreviation refers to a test used to assess glucose tolerance?
Which abbreviation refers to a test used to assess glucose tolerance?
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What does the abbreviation HRT stand for in medical context?
What does the abbreviation HRT stand for in medical context?
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Which abbreviation is associated with antibiotic-resistant bacteria?
Which abbreviation is associated with antibiotic-resistant bacteria?
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What does the abbreviation DVT stand for in medical context?
What does the abbreviation DVT stand for in medical context?
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Which abbreviation refers to a type of diabetes requiring insulin treatment?
Which abbreviation refers to a type of diabetes requiring insulin treatment?
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What does the abbreviation N&V stand for in medical terms?
What does the abbreviation N&V stand for in medical terms?
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What does the abbreviation HCG stand for in medical terms?
What does the abbreviation HCG stand for in medical terms?
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What does the abbreviation IBD stand for?
What does the abbreviation IBD stand for?
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What does the medical abbreviation 'CRF' stand for?
What does the medical abbreviation 'CRF' stand for?
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Which of the following abbreviations represents a condition related to the heart?
Which of the following abbreviations represents a condition related to the heart?
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What does the abbreviation 'PTH' stand for in medical terms?
What does the abbreviation 'PTH' stand for in medical terms?
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What does the medical abbreviation 'NTG' stand for?
What does the medical abbreviation 'NTG' stand for?
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What does the abbreviation 'PE' stand for in medical context?
What does the abbreviation 'PE' stand for in medical context?
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What does the medical abbreviation 'PTT' stand for?
What does the medical abbreviation 'PTT' stand for?
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What does the abbreviation 'ESR' stand for in medical terms?
What does the abbreviation 'ESR' stand for in medical terms?
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What does the medical abbreviation 'CAD' stand for?
What does the medical abbreviation 'CAD' stand for?
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Which abbreviation refers to a type of diabetes requiring insulin treatment?
Which abbreviation refers to a type of diabetes requiring insulin treatment?
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What does the medical abbreviation 'CrCl' stand for?
What does the medical abbreviation 'CrCl' stand for?
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Which abbreviation represents a pulmonary function test?
Which abbreviation represents a pulmonary function test?
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What does the abbreviation 'NKDA' stand for in medical terms?
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What does the abbreviation 'PRN' stand for in medical context?
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What does the abbreviation 'Amp' represent in medical terms?
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Which abbreviation is associated with osteoarthritis?
Which abbreviation is associated with osteoarthritis?
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What does the medical abbreviation 'Syr' stand for?
What does the medical abbreviation 'Syr' stand for?
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What does the abbreviation 'O.D.' stand for in medical context?
What does the abbreviation 'O.D.' stand for in medical context?
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Which abbreviation represents a condition related to the liver?
Which abbreviation represents a condition related to the liver?
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What does the abbreviation 'BTW' stand for in medical terms?
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What does the medical abbreviation 'Ax' represent?
What does the medical abbreviation 'Ax' represent?
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Which of the following abbreviations refers to a type of diabetes insipidus?
Which of the following abbreviations refers to a type of diabetes insipidus?
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What does the abbreviation 'TDS' stand for in medical context?
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What does the medical abbreviation 'GFR' stand for?
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Which abbreviation represents a condition related to the respiratory system?
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What does the abbreviation 'liq' represent in medical terms?
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Which abbreviation is associated with eye care?
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What does the abbreviation 'PKU' stand for in medical terms?
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Which abbreviation refers to a type of diabetes requiring insulin treatment?
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Study Notes
- Azithromycin is a widely used antibiotic with diverse applications in treating various bacterial infections.
- It is effective against Acute bacterial sinusitis caused by H. influenzae, M. catarrhalis, or S. pneumoniae, and Acute otitis media caused by H. influenzae, M. catarrhalis or S. pneumoniae. However, it's not a first-line treatment for these conditions.
- Azithromycin is used for treating Community-acquired pneumonia due to C. pneumoniae, H. influenzae, M. pneumoniae, or S. pneumoniae, Genital ulcer disease (chancroid) in men due to H. ducreyi, Pharyngitis or tonsillitis caused by S. pyogenes, and preventing and treating acute bacterial exacerbations of chronic obstructive pulmonary disease due to H. influenzae, M. catarrhalis, or S. pneumoniae.
- Azithromycin has a broad but shallow antibacterial activity. It inhibits some Gram-positive bacteria, some Gram-negative bacteria, and many atypical bacteria.
- Azithromycin is not widely used as monotherapy for Neisseria gonorrhoeae due to low barrier to resistance development.
- Extensive use of azithromycin has resulted in growing Streptococcus pneumoniae resistance.
- Some common side effects of azithromycin include diarrhea (5%), nausea (3%), and abdominal pain (3%). Less than 1% of people stop taking the drug due to side effects.
- Serious side effects include nervousness, skin reactions, anaphylaxis, Clostridium difficile infection, hearing loss, cholestatic hepatitis, delirium, and heart block. The drug interacts with certain drugs used to treat abnormal heart rhythms and can cause abnormal changes in the electrical activity of the heart.
- Azithromycin is effective against aerobic and facultative Gram-positive microorganisms such as Staphylococcus aureus (Methicillin-sensitive only), Streptococcus agalactiae, Streptococcus pneumoniae, Streptococcus pyogenes, and aerobic and facultative anaerobic Gram-negative microorganisms like Bordetella pertussis, Haemophilus ducreyi, Haemophilus influenzae, Legionella pneumophila, Moraxella catarrhalis, and Neisseria gonorrhoeae.
- The safety of azithromycin during pregnancy and breastfeeding is unclear, but no harm has been found during pregnancy and only low levels are found in breast milk. It's recommended to use azithromycin with caution during breastfeeding.
- Azithromycin appears to be effective in treating chronic obstructive pulmonary disease and potentially useful in asthma and sinusitis due to its suppression of inflammatory processes.
- Azithromycin prevents bacteria from growing by interfering with their protein synthesis. It binds to the 50S subunit of the bacterial ribosome, thus inhibiting translation of mRNA. Nucleic acid synthesis is not affected.
- Azithromycin is an acid-stable antibiotic, so it can be taken orally with no need of protection from gastric acids. It is readily absorbed, but absorption is greater on an empty stomach. Time to peak concentration (Tmax) in adults is 2.1 to 3.2 hours for oral dosage forms. Due to its high concentration in phagocytes, azithromycin is actively transported to the site of infection. During active phagocytosis, large concentrations are released. The concentration of azithromycin in the tissues can be over 50 times higher than in plasma due to ion trapping and its high lipid solubility.
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Description
Test your knowledge about Azithromycin, an antibiotic medication used to treat various bacterial infections such as middle ear infections, strep throat, and pneumonia. Learn about its uses, side effects, and more!