Autoregulation of Blood Flow Mechanisms
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Questions and Answers

What is the main mechanism behind myogenic autoregulation of blood flow?

  • Increased tissue metabolism
  • Accumulation of vasodilator metabolites
  • Vascular smooth muscle response to stretch (correct)
  • Release of vasodilator prostaglandins
  • Which of the following is not an example of a vasodilator metabolite that contributes to metabolic autoregulation?

  • K+ (correct)
  • Adenosine
  • CO2
  • Histamine
  • How does increased tissue metabolism affect arterioles and precapillary sphincters in metabolic autoregulation?

  • Causes relaxation (correct)
  • Induces hyperpolarization
  • Has no effect
  • Causes vasoconstriction
  • What happens when hypoxia occurs in the context of metabolic autoregulation?

    <p>Opens ATP-sensitive K+ channels causing vasodilatation</p> Signup and view all the answers

    Which vasodilator metabolite is especially found in the brain and skin for metabolic autoregulation?

    <p>Adenosine</p> Signup and view all the answers

    What effect does local changes in interstitial fluid osmolarity have on smooth muscle in autoregulation?

    <p>Hyperpolarization</p> Signup and view all the answers

    What is the main site of peripheral resistance (PR) in the circulation?

    <p>Arterioles</p> Signup and view all the answers

    In the context of blood flow regulation, what condition leads to large reductions in blood flow due to mild narrowing?

    <p>Atherosclerosis</p> Signup and view all the answers

    What physiological process allows small changes in arteriolar diameter to lead to relatively large changes in blood flow?

    <p>Myogenic autoregulation</p> Signup and view all the answers

    What type of blood flow involves all particles flowing parallel to the wall of the tube, but not at the same velocity?

    <p>Laminar Flow</p> Signup and view all the answers

    Which factor leads to blood flow changes aimed at increasing the blood supply to active tissues?

    <p>Accumulation of vasodilator metabolites</p> Signup and view all the answers

    What type of flow results from changes in blood velocity turning streamline flow into a more chaotic state?

    <p>Turbulent Flow</p> Signup and view all the answers

    What factors determine blood flow in a vessel?

    <p>Pressure gradient and resistance</p> Signup and view all the answers

    How does increased hematocrit affect blood flow in a vessel?

    <p>Increases viscosity and decreases flow</p> Signup and view all the answers

    Which of the following is a mechanism of metabolic autoregulation of blood flow?

    <p>Accumulation of vasodilator metabolites</p> Signup and view all the answers

    How does the length of a vessel affect blood flow?

    <p>Directly proportional to resistance</p> Signup and view all the answers

    Which factor has the most significant effect on the resistance encountered by blood in a vessel?

    <p>Radius of the vessel</p> Signup and view all the answers

    What role do vasoactive substances play in arteriolar diameter and blood flow?

    <p>They can dilate or constrict arterioles to regulate blood flow</p> Signup and view all the answers

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