Coronary Blood Flow Autoregulation Quiz
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Questions and Answers

What is the primary controller of coronary blood flow according to the text?

  • Neural factors
  • Vasodilator metabolites (correct)
  • Opening of ATP-sensitive K+ channels
  • Pressure changes in the aorta
  • Which factor can induce vasodilatation in coronary circulation due to lack of oxygen?

  • Increased local concentrations of lactate
  • Increased local concentrations of prostaglandins
  • Increased local concentrations of H+ (correct)
  • Increased local concentrations of K+
  • What is the mechanism by which hypoxia can increase coronary blood flow according to the text?

  • Increased smooth muscle contraction
  • Decreased smooth muscle relaxation
  • Opening of ATP-sensitive K+ channels (correct)
  • Closure of ATP-sensitive K+ channels
  • What induces reactive hyperemia in the area supplied by a coronary artery if it's occluded and then released according to the text?

    <p>Increased local concentrations of adenosine</p> Signup and view all the answers

    Which factor does NOT play a role in inducing vasodilatation in coronary circulation according to the text?

    <p>Increased local concentrations of Na+</p> Signup and view all the answers

    What type of tachycardia overrides the reduction in left ventricular coronary flow according to the text?

    <p>Sinus tachycardia</p> Signup and view all the answers

    What is the role of α-adrenergic receptors in coronary arterioles?

    <p>Mediate vasoconstriction</p> Signup and view all the answers

    How does norepinephrine affect coronary vasculature?

    <p>Causes vasoconstriction</p> Signup and view all the answers

    What is the mechanism behind vagal fibers' effect on coronary vessels?

    <p>Release of nitric oxide</p> Signup and view all the answers

    In the presence of a β-adrenergic blocking drug, what effect does noradrenergic stimulation have on coronary blood flow?

    <p>Vasoconstriction</p> Signup and view all the answers

    What is the consequence of systemic blood pressure falling on coronary blood flow regulation?

    <p>Increased coronary blood flow</p> Signup and view all the answers

    Which of the following statements is correct regarding coronary blood flow at rest?

    <p>The myocardium receives approximately 5% of the cardiac output.</p> Signup and view all the answers

    What is the primary mechanism by which the myocardium increases its oxygen consumption during exercise?

    <p>By increasing the coronary blood flow.</p> Signup and view all the answers

    Which region of the myocardium is most susceptible to ischemic damage and the most common site of myocardial infarction?

    <p>The subendocardial layers of the left ventricle.</p> Signup and view all the answers

    Which of the following factors is primarily responsible for the regulation of coronary blood flow during exercise?

    <p>Local metabolic factors released by the myocardium.</p> Signup and view all the answers

    What is the mechanism behind the phenomenon of reactive hyperemia in the coronary circulation?

    <p>Accumulation of vasodilator metabolites during periods of reduced blood flow.</p> Signup and view all the answers

    Which of the following statements accurately describes the phasic changes in coronary blood flow during the cardiac cycle?

    <p>Blood flow to the subendocardial layers of the left ventricle occurs only during diastole.</p> Signup and view all the answers

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