Coronary Blood Flow Autoregulation Quiz

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What is the primary controller of coronary blood flow according to the text?

Neural factors

Vasodilator metabolites (correct)

Opening of ATP-sensitive K+ channels

Pressure changes in the aorta

Which factor can induce vasodilatation in coronary circulation due to lack of oxygen?

Increased local concentrations of lactate

Increased local concentrations of prostaglandins

Increased local concentrations of H+ (correct)

Increased local concentrations of K+

What is the mechanism by which hypoxia can increase coronary blood flow according to the text?

Increased smooth muscle contraction

Decreased smooth muscle relaxation

Opening of ATP-sensitive K+ channels (correct)

Closure of ATP-sensitive K+ channels

What induces reactive hyperemia in the area supplied by a coronary artery if it's occluded and then released according to the text?

Increased local concentrations of adenosine Signup and view all the answers

Which factor does NOT play a role in inducing vasodilatation in coronary circulation according to the text?

Increased local concentrations of Na+ Signup and view all the answers

What type of tachycardia overrides the reduction in left ventricular coronary flow according to the text?

Sinus tachycardia Signup and view all the answers

What is the role of α-adrenergic receptors in coronary arterioles?

Mediate vasoconstriction Signup and view all the answers

How does norepinephrine affect coronary vasculature?

Causes vasoconstriction Signup and view all the answers

What is the mechanism behind vagal fibers' effect on coronary vessels?

Release of nitric oxide Signup and view all the answers

In the presence of a β-adrenergic blocking drug, what effect does noradrenergic stimulation have on coronary blood flow?

Vasoconstriction Signup and view all the answers

What is the consequence of systemic blood pressure falling on coronary blood flow regulation?

Increased coronary blood flow Signup and view all the answers

Which of the following statements is correct regarding coronary blood flow at rest?

The myocardium receives approximately 5% of the cardiac output. Signup and view all the answers

What is the primary mechanism by which the myocardium increases its oxygen consumption during exercise?

By increasing the coronary blood flow. Signup and view all the answers

Which region of the myocardium is most susceptible to ischemic damage and the most common site of myocardial infarction?

The subendocardial layers of the left ventricle. Signup and view all the answers

Which of the following factors is primarily responsible for the regulation of coronary blood flow during exercise?

Local metabolic factors released by the myocardium. Signup and view all the answers

What is the mechanism behind the phenomenon of reactive hyperemia in the coronary circulation?

Accumulation of vasodilator metabolites during periods of reduced blood flow. Signup and view all the answers

Which of the following statements accurately describes the phasic changes in coronary blood flow during the cardiac cycle?

Blood flow to the subendocardial layers of the left ventricle occurs only during diastole. Signup and view all the answers