Podcast
Questions and Answers
Which form of pemphigus is characterized by lesions formed just above the basal cell layer?
Which form of pemphigus is characterized by lesions formed just above the basal cell layer?
- Pemphigus erythematosus
- Discoid Lupus Erythematosus
- Pemphigus foliaceus
- Pemphigus vulgaris (correct)
Which breed seems to be over-represented in cases of pemphigus foliaceus?
Which breed seems to be over-represented in cases of pemphigus foliaceus?
- Labradors
- Chow Chows
- Akitas
- B and C (correct)
What are the primary lesions associated with pemphigus foliaceus?
What are the primary lesions associated with pemphigus foliaceus?
- Pustules (correct)
- Alopecia
- Collarettes
- Crusts
Which autoimmune skin disease is considered the most common in dogs and cats?
Which autoimmune skin disease is considered the most common in dogs and cats?
What is the condition characterized by a specific humoral or cell-mediated immune response against the component of adhesion molecules on keratinocytes?
What is the condition characterized by a specific humoral or cell-mediated immune response against the component of adhesion molecules on keratinocytes?
What are the superficial forms of pemphigus?
What are the superficial forms of pemphigus?
What is the hallmark of pemphigus?
What is the hallmark of pemphigus?
In which locations are the lesions typically found in pemphigus foliaceus?
In which locations are the lesions typically found in pemphigus foliaceus?
What are the systemic signs associated with pemphigus foliaceus?
What are the systemic signs associated with pemphigus foliaceus?
What are the targeted adhesion molecules in pemphigus complex?
What are the targeted adhesion molecules in pemphigus complex?
What is a common presentation of pemphigus foliaceus in cats and dogs?
What is a common presentation of pemphigus foliaceus in cats and dogs?
Which diagnostic methods are involved in the diagnosis of pemphigus foliaceus?
Which diagnostic methods are involved in the diagnosis of pemphigus foliaceus?
Which form of pemphigus is uncommon in dogs and rare in cats?
Which form of pemphigus is uncommon in dogs and rare in cats?
What are the common affected breeds with increased incidence of pemphigus erythematosus?
What are the common affected breeds with increased incidence of pemphigus erythematosus?
What regions are affected by pemphigus vulgaris?
What regions are affected by pemphigus vulgaris?
What are the common clinical signs of animals affected by pemphigus?
What are the common clinical signs of animals affected by pemphigus?
What conditions are part of the differential diagnosis for pemphigus foliaceus?
What conditions are part of the differential diagnosis for pemphigus foliaceus?
What do cytology and histopathology show in pemphigus vulgaris?
What do cytology and histopathology show in pemphigus vulgaris?
What is the rare form of pemphigus that is severe and affects mucocutaneous regions?
What is the rare form of pemphigus that is severe and affects mucocutaneous regions?
What is a rare presentation of pemphigus foliaceus in cats?
What is a rare presentation of pemphigus foliaceus in cats?
Which autoimmune skin disease involves hair follicles and requires aggressive treatment?
Which autoimmune skin disease involves hair follicles and requires aggressive treatment?
What is hypothesized to trigger Discoid Lupus Erythematosus (DLE) in dogs?
What is hypothesized to trigger Discoid Lupus Erythematosus (DLE) in dogs?
What are the clinical signs of DLE in dogs?
What are the clinical signs of DLE in dogs?
What is a potential complication of treatment for autoimmune skin diseases in dogs and cats?
What is a potential complication of treatment for autoimmune skin diseases in dogs and cats?
What is included in the treatment for Discoid Lupus Erythematosus (DLE) in dogs?
What is included in the treatment for Discoid Lupus Erythematosus (DLE) in dogs?
What may not be diagnostic for Discoid Lupus Erythematosus (DLE) in dogs?
What may not be diagnostic for Discoid Lupus Erythematosus (DLE) in dogs?
What is the second most common autoimmune skin disease in dogs?
What is the second most common autoimmune skin disease in dogs?
What is a differential diagnosis for DLE in dogs?
What is a differential diagnosis for DLE in dogs?
What may show characteristic changes in the diagnosis of DLE in dogs?
What may show characteristic changes in the diagnosis of DLE in dogs?
What may be required for severe cases of DLE in dogs?
What may be required for severe cases of DLE in dogs?
Study Notes
Autoimmune Skin Diseases in Dogs and Cats
- Pemphigus Complex involves hair follicles and requires aggressive treatment
- Treatment includes oral glucocorticoids, cytotoxic drugs, glucocorticoid pulse therapy, mycophenolate mofetil, and leflunomide
- Patient response to therapy is unpredictable, and there are potentially severe side effects
- Complications of treatment include drug adverse effects, secondary infections, and demodicosis
- Discoid Lupus Erythematosus (DLE) is the second most common autoimmune skin disease in dogs
- DLE is hypothesized to be triggered by ultraviolet light and specific autoantibodies
- Clinical signs of DLE include nasal depigmentation, ulcers, and crusts exacerbated by sunlight
- Differential diagnoses for DLE include nasal pyoderma, pemphigus foliaceus, and uveodermatologic syndrome
- Cytology may show no significant findings, while histopathology reveals characteristic changes
- Direct immunofluorescence may not be diagnostic for DLE
- Treatment for DLE includes systemic vitamin E, tetracycline and niacinamide, topical steroids, and tacrolimus
- Severe cases may require systemic steroids, oral cyclosporine, and lifelong treatment with sun precautions
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Description
Test your knowledge of autoimmune skin diseases in dogs and cats with this quiz. Explore topics such as Pemphigus Complex, Discoid Lupus Erythematosus (DLE), treatment options, and differential diagnoses.