Autoimmune skin diseases quiz

T-cells

Depigmentation caused by any inflammatory disease

T-cells

<p>Both tumours and deep infections</p> Signup and view all the answers

<p>Dermal blood vessels</p> Signup and view all the answers

<p>Antibodies</p> Signup and view all the answers

<p>Subcuticular fat</p> Signup and view all the answers

<p>Epitheliotropic lymphoma</p> Signup and view all the answers

<p>Type III</p> Signup and view all the answers

<p>Desmosomal proteins in upper part of epidermis</p> Signup and view all the answers

<p>Basal epidermis cells</p> Signup and view all the answers

<p>Pustules rapidly developing into crusts</p> Signup and view all the answers

<p>Superficial pyoderma</p> Signup and view all the answers

<p>Type IV</p> Signup and view all the answers

<p>Desmosomal proteins in upper epidermis</p> Signup and view all the answers

<p>Antibody attack</p> Signup and view all the answers

<p>Layers of heaped crusts</p> Signup and view all the answers

<p>Superficial pyoderma</p> Signup and view all the answers

<p>Autoimmune disease</p> Signup and view all the answers

<p>Mycobacteria infections</p> Signup and view all the answers

<p>Kidneys</p> Signup and view all the answers

<p>To detect abnormal immune cells</p> Signup and view all the answers

<p>Biopsy from an area of no self-trauma</p> Signup and view all the answers

<p>Fever</p> Signup and view all the answers

<p>Bacterial infection</p> Signup and view all the answers

<p>To identify common differential diagnoses</p> Signup and view all the answers

<p>4-6</p> Signup and view all the answers

<p>Desmosomal proteins in the upper epidermis, cells of the basal epidermis, sebaceous glands, dermal skin vessels, subcuticular fat</p> Signup and view all the answers

<p>Type II (antibodies - IgG), Type III (immune-complex disease), Type IV (T-cells)</p> Signup and view all the answers

<p>Pustules rapidly developing into crusts, leaving erosions</p> Signup and view all the answers

<p>Sterile pyogranulomatous dermatitis and panniculitis (SPDP)</p> Signup and view all the answers

<p>Superficial pyoderma</p> Signup and view all the answers

<ol> <li>pancreatic neoplasia 2. pancreatitis 3. polyarthritis 4. systemic lupus erythematosus</li> </ol> Signup and view all the answers

<p>Kidneys (glomerulonephropathy), joints (immune-mediated arthropathy), and eyes (retinal haemorrhage)</p> Signup and view all the answers

<p>To rule out common differential diagnoses</p> Signup and view all the answers

<p>4-6 biopsies</p> Signup and view all the answers

<p>The tissue/antigen involved is the main determinant of the clinical signs</p> Signup and view all the answers

<p>Main differential diagnoses for facial cutaneous lupus erythematosus include mucocutaneous pyoderma and epitheliotropic lymphoma.</p> Signup and view all the answers

<p>The immune mechanism involved in vasculitis is antibody (± antibody–immune complexes).</p> Signup and view all the answers

<p>The main target tissue of antibody attack in cutaneous immune-mediated diseases (CIMDs) is dermal blood vessels.</p> Signup and view all the answers

<p>The main target of the antibody attack in Pemphigus foliaceus is desmoglein-1, a protein present in the desmosomes of keratinocytes.</p> Signup and view all the answers

<p>The main differential diagnosis for panniculitis includes tumors and deep infections (e.g., M. bovis).</p> Signup and view all the answers