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Autoimmune Polyendocrinopathies Quiz
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Autoimmune Polyendocrinopathies Quiz

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Questions and Answers

Which syndrome is associated with X-linked polyendocrinopathy, immune dysfunction, and diarrhea syndrome?

  • IPEX syndrome (correct)
  • Polygenic mutation syndrome
  • Autoimmune polyendocrine syndrome type 2 (APS-2)
  • Schmidt syndrome

    • What is the main role of the autoimmune regulator gene (AIRE) in autoimmune polyendocrine syndrome type I (APS-1)?

  • Regulates insulin production
  • Causes enamel hypoplasia
  • Triggers adrenal insufficiency (correct)
  • Controls ectodermal development

    • In autoimmune polyendocrine syndrome type 2 (APS-2), which condition is commonly observed?

  • Type 1 diabetes (correct)
  • Adrenal insufficiency
  • Hypoparathyreosis
  • Candidiasis

    • What is the significance of Forkhead transcription factor (FOXP) in autoimmune polyendocrine syndromes?

    <p>Essential for ectodermal development</p> Signup and view all the answers

    Which of the following is a characteristic manifestation of autoimmune polyendocrine syndrome type 1 (APS-1)?

    <p>Enamel hypoplasia</p> Signup and view all the answers

    What is the role of peripheral antigen-expressing cells (PAE cells) in autoimmune polyendocrine syndromes?

    <p>Regulate immune responses in the thymus</p> Signup and view all the answers

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