Autoimmune Disorders and Hormone Overproduction Quiz

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Which type of hypersensitivity reaction involves the formation of immune complexes that lead to chronic inflammation and tissue destruction?

Type III

In which type of hypersensitivity reaction are cytotoxic T cells typically involved?

Type IV

Which type of hypersensitivity reaction is responsible for the Arthus reaction?

Type II

Which hypersensitivity reaction is characterized by the presence of autoantibodies against self-tissues or organs?

<p>Type II</p> Signup and view all the answers

Which type of hypersensitivity reaction is involved in allergic contact dermatitis caused by poison ivy?

<p>Type IV</p> Signup and view all the answers

Which type of hypersensitivity reactions can destroy or alter cells by four mechanisms?

<p>Type II allergies</p> Signup and view all the answers

What is the main mediator responsible for the clinical manifestations of Type I allergies?

<p>Histamine</p> Signup and view all the answers

Which type of allergy is IgE mediated and requires sensitization by repeated exposure to allergens?

<p>Type I allergies</p> Signup and view all the answers

What characterizes Type III allergies?

<p>They involve antigen-antibody complexes deposited in vessel walls or tissues</p> Signup and view all the answers

Which type of allergy is characterized by a delayed hypersensitivity reaction mediated by T cells?

<p>Type IV allergies</p> Signup and view all the answers

What is the cause of hyperthyroidism?

<p>Abnormal stimulation of cells leading to overproduction of a hormone</p> Signup and view all the answers

Which autoimmune disease involves the binding of autoantibodies to acetylcholine receptors?

<p>Myasthenia gravis</p> Signup and view all the answers

What is the main characteristic of Multiple Sclerosis?

<p>Relapsing-remitting disease pattern</p> Signup and view all the answers

How does Type I diabetes differ from Type II diabetes?

<p>Type I diabetes leads to destruction of beta cells</p> Signup and view all the answers

What role do T cells play in neuromuscular autoimmunities?

<p>Reduce neurons' ability to send impulses</p> Signup and view all the answers

Which type of allergic reaction is characterized by local and systemic reactions such as urticaria and bronchospasm?

<p>Type I</p> Signup and view all the answers

What is a rare disorder characterized by mast cell proliferation leading to symptoms like flushing, abdominal pain, and hypotension?

<p>Mastocytosis</p> Signup and view all the answers

Which type of allergic reaction is triggered by insulin and usually involves local reactions that disappear after the first 4 weeks of therapy?

<p>Type II</p> Signup and view all the answers

What type of allergic reaction is often associated with latex allergies and can present as anaphylaxis in certain individuals?

<p>Type I</p> Signup and view all the answers

Which type of allergic reaction is typically delayed and mediated by T cells, causing symptoms like syncope and musculoskeletal pain?

<p>Type IV</p> Signup and view all the answers

Which type of allergies mainly affect children and cause skin rash?

<p>Cutaneous allergies</p> Signup and view all the answers

What is the main mediator responsible for the clinical manifestations of Type II allergies?

<p>Complement-mediated lysis</p> Signup and view all the answers

Which type of hypersensitivity reaction involves antigen-antibody complexes deposited in vessel walls or extravascular tissue?

<p>Type III allergies</p> Signup and view all the answers

Which type of allergic reaction is characterized by contact dermatitis caused by poison ivy and metals?

<p>Type IV</p> Signup and view all the answers

In Type I allergies, what is released by mast cells during degranulation that contributes to the clinical manifestations?

<p>Histamine</p> Signup and view all the answers

What type of hypersensitivity reaction is involved in the rejection of a transplanted kidney?

<p>Type IV</p> Signup and view all the answers

Which type of hypersensitivity reaction is characterized by Tc cell destruction of target cells?

<p>Type II allergies</p> Signup and view all the answers

In which type of allergic reaction does autoantibody binding to self-tissues typically occur, leading to chronic inflammation and joint destruction?

<p>Type III</p> Signup and view all the answers

Which type of hypersensitivity reaction involves the production of autoantibodies against organs and tissues, as seen in diseases like Systemic Lupus Erythematosus (SLE)?

<p>Type II</p> Signup and view all the answers

What type of immune response is responsible for allergic reactions to pollens, dust mites, and animal dander?

<p>Humoral</p> Signup and view all the answers

Which type of allergic reaction is often associated with food-dependent exercise-induced anaphylaxis?

<p>Type I</p> Signup and view all the answers

What type of allergic reaction involves the formation of immune complexes leading to chronic inflammation and tissue destruction?

<p>Type III</p> Signup and view all the answers

Which type of allergy is more likely to involve local reactions that disappear after the first 4 weeks of therapy?

<p>Insulin allergy</p> Signup and view all the answers

In which type of hypersensitivity reaction are cytotoxic T cells typically involved?

<p>Type II</p> Signup and view all the answers

What characterizes Type IV hypersensitivity reactions?

<p>Delayed hypersensitivity mediated by T cells</p> Signup and view all the answers

What type of hypersensitivity reaction is commonly triggered by insulin and involves local reactions that usually disappear after the first 4 weeks of therapy?

<p>Type II</p> Signup and view all the answers

Which type of hypersensitivity reaction involves the presence of autoantibodies against self-tissues or organs?

<p>Type III</p> Signup and view all the answers

In which type of allergic reaction are cytotoxic T cells typically involved, leading to cellular destruction or alteration?

<p>Type II allergies</p> Signup and view all the answers

What characterizes Type IV allergies?

<p>Delayed and T cell mediated</p> Signup and view all the answers

Which type of hypersensitivity reaction is associated with local and systemic reactions such as urticaria and bronchospasm?

<p>Type I allergies</p> Signup and view all the answers

Study Notes

Hypersensitivity Reactions

  • Type III hypersensitivity reaction involves the formation of immune complexes that lead to chronic inflammation and tissue destruction.

Cytotoxic T Cells

  • Cytotoxic T cells are typically involved in Type IV hypersensitivity reactions.

Arthus Reaction

  • The Arthus reaction is a Type III hypersensitivity reaction.

Autoantibodies

  • Autoantibodies against self-tissues or organs characterize Type II hypersensitivity reactions.

Allergic Contact Dermatitis

  • Allergic contact dermatitis caused by poison ivy involves Type IV hypersensitivity reactions.

Cell Destruction

  • Type II hypersensitivity reactions can destroy or alter cells by four mechanisms.

Type I Allergies

  • Histamine is the main mediator responsible for the clinical manifestations of Type I allergies.
  • Type I allergies are IgE-mediated and require sensitization by repeated exposure to allergens.

Type III Allergies

  • Type III allergies are characterized by the presence of immune complexes leading to chronic inflammation and tissue destruction.

Type IV Allergies

  • Type IV allergies are characterized by a delayed hypersensitivity reaction mediated by T cells.

Hyperthyroidism

  • Hyperthyroidism is caused by Graves' disease, an autoimmune disease.

Autoimmune Disease

  • Myasthenia gravis is an autoimmune disease involving the binding of autoantibodies to acetylcholine receptors.

Multiple Sclerosis

  • Multiple Sclerosis is characterized by demyelination of the nervous system.

Diabetes

  • Type I diabetes differs from Type II diabetes in that it involves the destruction of pancreatic beta cells, leading to an absolute insulin deficiency.

Neuromuscular Autoimmunities

  • T cells play a role in neuromuscular autoimmunities by destroying or altering cells.

Allergic Reactions

  • Anaphylaxis is a Type I allergic reaction characterized by local and systemic reactions such as urticaria and bronchospasm.

Mastocytosis

  • Mastocytosis is a rare disorder characterized by mast cell proliferation leading to symptoms like flushing, abdominal pain, and hypotension.

Insulin Allergy

  • Insulin allergy is a Type I allergic reaction usually involving local reactions that disappear after the first 4 weeks of therapy.

Latex Allergy

  • Latex allergy is a Type IV allergic reaction often associated with anaphylaxis in certain individuals.

Contact Dermatitis

  • Contact dermatitis caused by poison ivy and metals involves Type IV hypersensitivity reactions.

Mast Cell Degranulation

  • During degranulation, mast cells release histamine, which contributes to the clinical manifestations of Type I allergies.

Transplant Rejection

  • Transplant rejection involves a Type IV hypersensitivity reaction.

Tc Cell Destruction

  • Tc cells are involved in the destruction of target cells in Type IV hypersensitivity reactions.

Autoantibodies

  • Autoantibodies against self-tissues typically occur in Type III hypersensitivity reactions, leading to chronic inflammation and joint destruction.

Systemic Lupus Erythematosus (SLE)

  • SLE is a Type III hypersensitivity reaction involving the production of autoantibodies against organs and tissues.

Allergic Reactions

  • Allergic reactions to pollens, dust mites, and animal dander involve a Type I immune response.

Exercise-Induced Anaphylaxis

  • Exercise-induced anaphylaxis is often associated with Type I allergic reactions to food.

Immune Complexes

  • Type III hypersensitivity reactions involve the formation of immune complexes leading to chronic inflammation and tissue destruction.

Local Reactions

  • Insulin allergy is a Type I allergic reaction characterized by local reactions that usually disappear after the first 4 weeks of therapy.

Cytotoxic T Cells

  • Cytotoxic T cells are typically involved in Type IV hypersensitivity reactions, leading to cellular destruction or alteration.

Type IV Allergies

  • Type IV allergies are characterized by a delayed hypersensitivity reaction mediated by T cells.

Autoantibodies

  • Autoantibodies against self-tissues or organs characterize Type II hypersensitivity reactions.

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