Parasympatholitics PHARM TEST
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Questions and Answers

What is the lethal dosage of Atropine in adults?

  • 10 mg
  • 50 mg
  • 100 mg (correct)
  • 1 mg
  • Which of the following is an ocular side effect associated with Atropine?

  • Decreased salivation
  • Increased tear production
  • Facial flushing (correct)
  • Decrease in intraocular pressure
  • What is the specific antidote for Atropine toxicity?

  • Succinylcholine
  • Naloxone
  • Diazepam
  • Physostigmine (correct)
  • In which condition is Atropine useful as a treatment in ophthalmology?

    <p>Amblyopia</p> Signup and view all the answers

    What are the initial signs of systemic side effects of Atropine?

    <p>Dryness of mouth and skin</p> Signup and view all the answers

    In whom should extreme caution be taken with the administration of Atropine?

    <p>Children aged 6-12 years old</p> Signup and view all the answers

    Which receptor subtype is primarily affected by atropine as a cycloplegic agent?

    <p>M1 receptors</p> Signup and view all the answers

    What is the recommended antidote for Atropine toxicity?

    <p>Physostigmine</p> Signup and view all the answers

    Which of the following is a possible ocular side effect of Atropine use?

    <p>Increased intraocular pressure (IOP)</p> Signup and view all the answers

    What is a potential systemic side effect of Atropine administration?

    <p>Dry mouth</p> Signup and view all the answers

    In ophthalmology, what is a common clinical use of Atropine?

    <p>Prevention of posterior synechiae in uveitis</p> Signup and view all the answers

    Which pharmacological class does Atropine belong to when used as a cycloplegic agent?

    <p>Parasympatholytic</p> Signup and view all the answers

    What is the antidote for Atropine toxicity?

    <p>Physostigmine</p> Signup and view all the answers

    Which of the following statements regarding Atropine's ocular side effects is incorrect?

    <p>Full recovery within 24 hours</p> Signup and view all the answers

    What are the systemic side effects associated with Atropine use?

    <p>Increase in intraocular pressure in patients with primary open-angle glaucoma (POAG)</p> Signup and view all the answers

    In ophthalmology, what is a common clinical use of Atropine?

    <p>Drug of choice for cycloplegic refraction</p> Signup and view all the answers

    Which statement is true about Cyclopentolate as compared to Atropine?

    <p>Less mydriatic and cycloplegic effect on dark irides</p> Signup and view all the answers

    Which parasympatholytic agent has similar adverse effects to Atropine?

    <p>Scopolamine</p> Signup and view all the answers

    What is the specific antidote for Atropine toxicity?

    <p>Physostigmine</p> Signup and view all the answers

    What is the recommended dosage of physostigmine in adults for treating Atropine toxicity?

    <p>1-2mg</p> Signup and view all the answers

    What is the primary method of administration for physostigmine in children for Atropine toxicity?

    <p>Subcutaneous</p> Signup and view all the answers

    Which age group requires extreme caution when administering Atropine due to increased toxicity risks?

    <p>Children between 6-12 years old</p> Signup and view all the answers

    What are the initial signs of Atropine toxicity on the cardiovascular system?

    <p>Bradycardia</p> Signup and view all the answers

    Which medication is NOT a suitable antidote for Atropine toxicity?

    <p>Diazepam</p> Signup and view all the answers

    Which parasympatholytic agent, due to its toxicity, is not a drug of choice?

    <p>Scopolamine</p> Signup and view all the answers

    Which parasympatholytic agent has a commercial availability in 0.5%, 1.0%, and 2.0%?

    <p>Cyclopentolate</p> Signup and view all the answers

    Which parasympatholytic agent is an alternative treatment when an allergic reaction to Atropine occurs?

    <p>Scopolamine</p> Signup and view all the answers

    Which parasympatholytic agent has a shorter duration of mydriatic and cycloplegic action compared to Atropine?

    <p>Homatropine</p> Signup and view all the answers

    Which parasympatholytic agent is an adjunct treatment for iridocyclitis but should not be used for accommodative esotropia?

    <p>Homatropine</p> Signup and view all the answers

    Which parasympatholytic agent has a mydriatic and cycloplegic effect of shorter duration due to its concentration?

    <p>Scopolamine</p> Signup and view all the answers

    Which medication is the antidote for Atropine toxicity?

    <p>Edrophonium Chloride</p> Signup and view all the answers

    What is the main effect of Atropine on the post-ganglionic effector structures in the eye?

    <p>Dilation of the iris</p> Signup and view all the answers

    What is the mechanism of action of Pilocarpine in the context of Atropine toxicity?

    <p>Stimulates M3 receptors</p> Signup and view all the answers

    In Lambert-Eaton Myasthenic Syndrome, how does the autoimmune disorder affect the neuromuscular junction?

    <p>Affects voltage-gated calcium channels</p> Signup and view all the answers

    What role does the E-W nucleus play in the efferent oculo-parasympathetic pathway?

    <p>Serves as an origin point</p> Signup and view all the answers

    Which condition is treated with steroids in Lambert-Eaton Myasthenic Syndrome?

    <p>Lambert-Eaton Myasthenic Syndrome</p> Signup and view all the answers

    What is the primary neurotransmitter involved in both pre and post-ganglionic synapses in the oculo-parasympathetic pathway?

    <p>5000</p> Signup and view all the answers

    Which medication class does Atropine belong to when used as a cycloplegic agent?

    <p><strong>Ocular Cholinergic Antagonists</strong></p> Signup and view all the answers

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