38 Questions
What is the lethal dosage of Atropine in adults?
100 mg
Which of the following is an ocular side effect associated with Atropine?
Facial flushing
What is the specific antidote for Atropine toxicity?
Physostigmine
In which condition is Atropine useful as a treatment in ophthalmology?
Amblyopia
What are the initial signs of systemic side effects of Atropine?
Dryness of mouth and skin
In whom should extreme caution be taken with the administration of Atropine?
Children aged 6-12 years old
Which receptor subtype is primarily affected by atropine as a cycloplegic agent?
M1 receptors
What is the recommended antidote for Atropine toxicity?
Physostigmine
Which of the following is a possible ocular side effect of Atropine use?
Increased intraocular pressure (IOP)
What is a potential systemic side effect of Atropine administration?
Dry mouth
In ophthalmology, what is a common clinical use of Atropine?
Prevention of posterior synechiae in uveitis
Which pharmacological class does Atropine belong to when used as a cycloplegic agent?
Parasympatholytic
What is the antidote for Atropine toxicity?
Physostigmine
Which of the following statements regarding Atropine's ocular side effects is incorrect?
Full recovery within 24 hours
What are the systemic side effects associated with Atropine use?
Increase in intraocular pressure in patients with primary open-angle glaucoma (POAG)
In ophthalmology, what is a common clinical use of Atropine?
Drug of choice for cycloplegic refraction
Which statement is true about Cyclopentolate as compared to Atropine?
Less mydriatic and cycloplegic effect on dark irides
Which parasympatholytic agent has similar adverse effects to Atropine?
Scopolamine
What is the specific antidote for Atropine toxicity?
Physostigmine
What is the recommended dosage of physostigmine in adults for treating Atropine toxicity?
1-2mg
What is the primary method of administration for physostigmine in children for Atropine toxicity?
Subcutaneous
Which age group requires extreme caution when administering Atropine due to increased toxicity risks?
Children between 6-12 years old
What are the initial signs of Atropine toxicity on the cardiovascular system?
Bradycardia
Which medication is NOT a suitable antidote for Atropine toxicity?
Diazepam
Which parasympatholytic agent, due to its toxicity, is not a drug of choice?
Scopolamine
Which parasympatholytic agent has a commercial availability in 0.5%, 1.0%, and 2.0%?
Cyclopentolate
Which parasympatholytic agent is an alternative treatment when an allergic reaction to Atropine occurs?
Scopolamine
Which parasympatholytic agent has a shorter duration of mydriatic and cycloplegic action compared to Atropine?
Homatropine
Which parasympatholytic agent is an adjunct treatment for iridocyclitis but should not be used for accommodative esotropia?
Homatropine
Which parasympatholytic agent has a mydriatic and cycloplegic effect of shorter duration due to its concentration?
Scopolamine
Which medication is the antidote for Atropine toxicity?
Edrophonium Chloride
What is the main effect of Atropine on the post-ganglionic effector structures in the eye?
Dilation of the iris
What is the mechanism of action of Pilocarpine in the context of Atropine toxicity?
Stimulates M3 receptors
In Lambert-Eaton Myasthenic Syndrome, how does the autoimmune disorder affect the neuromuscular junction?
Affects voltage-gated calcium channels
What role does the E-W nucleus play in the efferent oculo-parasympathetic pathway?
Serves as an origin point
Which condition is treated with steroids in Lambert-Eaton Myasthenic Syndrome?
Lambert-Eaton Myasthenic Syndrome
What is the primary neurotransmitter involved in both pre and post-ganglionic synapses in the oculo-parasympathetic pathway?
5000
Which medication class does Atropine belong to when used as a cycloplegic agent?
Ocular Cholinergic Antagonists
Test your knowledge on the clinical uses and ocular side effects of Atropine, a naturally occurring alkaloid from the plant Atropa belladona. Learn about its applications in cycloplegic refraction, treatment of myopia, and more.
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