ATI Pharmacology Made Easy: Pain and Inflammation

Questions and Answers

What should the client watch for as indications of an adverse reaction to celecoxib?

Weight gain

What is the purpose of the client taking low-dose aspirin daily?

Reduces the risks of a cardiovascular event

What instruction should the health care provider give regarding aspirin use before surgery?

Stop taking one week before surgery

What should be monitored when administering morphine IV for pain?

Respiratory depression Signup and view all the answers

What drug should the health care provider have available when administering morphine IV?

Naloxone Signup and view all the answers

What adverse drug reaction should a client taking aspirin look for?

Petechiae Signup and view all the answers

Which instructions should be included when talking to a client about taking oral morphine? (Select all that apply)

Do not take it before driving Signup and view all the answers

What precaution should a provider take when prescribing prednisone for a client with type 1 diabetes?

Increase serum glucose monitoring Signup and view all the answers

How long does it take for tramadol to take effect?

Allow 1 hr for it to take effect Signup and view all the answers

What condition does allopurinol help prevent in clients receiving chemotherapy?

Hyperuricemia Signup and view all the answers

What should the client watch for as an adverse reaction to celecoxib?

Weight gain Signup and view all the answers

Why does the client take low-dose aspirin in addition to celecoxib?

Reduces the risks of a cardiovascular event Signup and view all the answers

What instruction should be given regarding aspirin use prior to surgery?

Stop taking one week before surgery Signup and view all the answers

What should the health care provider monitor for when administering morphine IV?

Respiratory depression Signup and view all the answers

What drug should be available when administering morphine?

Naloxone Signup and view all the answers

What adverse drug reaction should be monitored for when taking aspirin?

Petechiae Signup and view all the answers

Match the following drugs with their classifications:

Morphine = Opioid analgesic Prednisone = Glucocorticoid Ibuprofen = Non-steroidal anti-inflammatory drug Naloxone = Opioid antagonist Signup and view all the answers

Which instructions should be given to a client about taking oral morphine? (Select all that apply)

Rise slowly from sitting or reclining Signup and view all the answers

What precaution should be taken when prescribing prednisone to a client with type 1 diabetes mellitus?

Increase serum glucose monitoring Signup and view all the answers

What is the expected time to onset of tramadol when used for pain management?

Allow 1 hr for it to take effect Signup and view all the answers

What condition should allopurinol be given to reduce the risk of during chemotherapy?

Hyperuricemia Signup and view all the answers

Match the drug with its indication:

Morphine = Sedation Acetaminophen = Fever reduction Butorphanol = Anesthesia adjunct Prednisone = Prevention of organ rejection Signup and view all the answers

What should be prepared for a client immediately following an acetaminophen overdose?

Acetylcysteine Signup and view all the answers

Who should butorphanol not be given to?

Clients using a fentanyl patch for chronic pain Signup and view all the answers

What should a client on celecoxib monitor for that indicates a serious reaction?

Black, tarry stools Signup and view all the answers

What precautions should a nurse teach a client prescribed allopurinol?

Avoid driving or activities that require mental alertness Signup and view all the answers

In which scenario is morphine contraindicated?

For a client who had a cholecystectomy Signup and view all the answers

Which drug interacts with allopurinol?

Warfarin Signup and view all the answers

What adverse drug reactions should be monitored for in a client taking butorphanol? (Select all that apply)

Headache Signup and view all the answers

What should a client report when taking aspirin for an ankle sprain?

Weight gain Signup and view all the answers

Which drug increases the risk of Reye Syndrome in children with viral infections?

Aspirin Signup and view all the answers

What instructions for prednisone should the nurse provide? (Select all that apply)

Increase intake of calcium and vitamin D Signup and view all the answers

What adverse effects should a client taking allopurinol report? (Select all that apply)

Vision changes Signup and view all the answers

What should be monitored for in a client taking furosemide and prednisone together?

Hypokalemia Signup and view all the answers

What is a contraindication for prescribing tramadol?

Seizure disorder Signup and view all the answers

What adverse drug reactions should the nurse tell the client taking celecoxib to report?

Chest pain Signup and view all the answers

What is a contraindication for celecoxib?

Sulfamide allergy Signup and view all the answers

What early indications of acetaminophen toxicity should a client report? (Select all that apply)

Nausea Signup and view all the answers

What instruction should be given about taking allopurinol?

Eat a small meal before taking this drug Signup and view all the answers

What instructions should be given to a client who has a new prescription for tramadol? (Select all that apply)

Increase fiber and fluid intake Signup and view all the answers

What manifestations should be monitored in an opioid-dependent client prescribed butorphanol? (Select all that apply)

Hypertension Signup and view all the answers

What adverse drug reactions should be monitored in a client receiving morphine? (Select all that apply)

Sedation Signup and view all the answers

What adverse drug reaction should a nurse monitor for in a client taking prednisone for rheumatoid arthritis?

Bone loss Signup and view all the answers

What manifestation of hypersensitivity syndrome should a nurse monitor in a client taking allopurinol?

Fever Signup and view all the answers

What adverse drug reactions should be monitored in a client receiving naloxone? (Select all that apply)

Ventricular arrhythmias Signup and view all the answers

What intervention should a nurse include for a client taking prednisone?

Monitor the client's blood glucose Signup and view all the answers

What conditions is acetaminophen indicated for? (Select all that apply)

To relieve mild pain Signup and view all the answers

What manifestations of salicylism should a nurse instruct the client taking aspirin to report? (Select all that apply)

Tinnitus Signup and view all the answers

What should a client taking low-dose aspirin to prevent cardiovascular events know about ibuprofen?

Ibuprofen will reduce the cardioprotective effects of low-dose aspirin Signup and view all the answers

What client condition is a contraindication for acetaminophen?

Alcohol use disorder Signup and view all the answers

Study Notes

Celecoxib (Celebrex) used for osteoarthritis may cause weight gain; clients should monitor and report this.
Aspirin is taken with celecoxib to reduce cardiovascular event risk.
Clients must discontinue aspirin one week before surgery to prevent bleeding.
Morphine IV can lead to respiratory depression; monitoring is essential during administration.
Naloxone should be readily available when administering morphine for potential overdose reversal.

Aspirin and Adverse Reactions

Clients starting aspirin for cardiovascular prevention must watch for petechiae as a potential adverse effect.
Weight gain should be reported by clients taking aspirin for conditions like ankle sprains.
Aspirin poses a risk of Reye Syndrome in children with viral infections.

Opioid and Non-Opioid Analgesics

Instructions for oral morphine include taking it with food and rising slowly to prevent dizziness.
Tramadol takes about one hour for effect; clients should be informed accordingly.
Butorphanol is contraindicated for clients using fentanyl patches due to potential safety issues.

Monitoring and Precautions

Increased serum glucose monitoring is essential for clients prescribed prednisone, especially those with diabetes.
Clients on allopurinol must monitor for sore throat, bruising, vertigo, and vision changes as adverse effects.
Concurrent use of furosemide and prednisone may result in hypokalemia; appropriate monitoring is advised.
Bone loss is a potential adverse reaction for clients on long-term prednisone treatment.

Toxicity and Overdoses

In cases of acetaminophen overdose, acetylcysteine is the antidote to prepare for administration.
Clients taking acetaminophen should report early toxicity signs like diaphoresis, nausea, and diarrhea.
Naloxone treatment for opioid toxicity requires monitoring for increased pain and respiratory rate changes.

Drug Interactions and Contraindications

Warfarin interacts with allopurinol; healthcare providers should review concurrent medications for potential interactions.
Celecoxib is contraindicated in clients with a sulfamide allergy; awareness of allergies is crucial for safe prescribing.
Acetaminophen is contraindicated in clients with alcohol use disorder due to liver safety concerns.

Client Education

Safety measures for clients starting new medications include instruction on gradual dose discontinuation for prednisone and monitoring for signs of gastric bleeding.
Clients taking tramadol should be informed to increase fiber and fluid intake to mitigate constipation risks.
Clients should be advised against driving or activities requiring alertness when starting new medications like allopurinol.

Summary of Common Analgesics

Effective use of analgesics includes knowing the adverse effects, monitoring requirements, and safe practices to minimize risks while managing pain.

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Description

Test your knowledge on the pharmacological aspects of pain and inflammation management in this flashcard quiz. Focus on the use of celecoxib and its interactions, indications, and possible adverse reactions. Ideal for nursing and pharmacy students preparing for exams.