Atherosclerosis
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Atherosclerosis

Created by
@EvocativeSense

Questions and Answers

Which step of the chronic inflammatory response involves the migration of lymphocytes into the intima?

Step Five

What is the consequence of atherosclerosis that occurs when the lipid core of a plaque is exposed?

Plaque rupture

What is the macroscopic appearance of a fatty streak?

Small yellow flat spots

What is the microscopic appearance of a stable plaque?

<p>Thickened fibrous caps with minimal lipid core</p> Signup and view all the answers

What is the consequence of plaque rupture in atherosclerosis?

<p>Formation of a blood clot</p> Signup and view all the answers

What is the consequence of an increase in lipid accumulation in atherosclerosis?

<p>Luminal narrowing</p> Signup and view all the answers

What is the consequence of luminal narrowing in atherosclerosis?

<p>Decrease in blood supply</p> Signup and view all the answers

What is the consequence of plaque rupture in atherosclerosis?

<p>Formation of a blood clot</p> Signup and view all the answers

What is the consequence of luminal obstruction in atherosclerosis?

<p>Infarction</p> Signup and view all the answers

What is the consequence of a blood clot formation in atherosclerosis?

<p>Luminal obstruction</p> Signup and view all the answers

Which of the following is the correct sequence of events in the development of atherosclerosis?

<p>Endothelial damage, monocyte migration, foam cell formation, fatty streak formation</p> Signup and view all the answers

What is the main cause of endothelial damage in atherosclerosis?

<p>LDL</p> Signup and view all the answers

What happens to monocytes in the development of atherosclerosis?

<p>They migrate through the endothelium</p> Signup and view all the answers

What are foam cells in the context of atherosclerosis?

<p>Macrophages or smooth muscle cells that engulf lipids</p> Signup and view all the answers

What is the earliest lesion of the atheroma called?

<p>Fatty streak</p> Signup and view all the answers

What is the main role of smooth muscle cells in the development of atherosclerosis?

<p>To provide structural support in the tunica media</p> Signup and view all the answers

What initiates the chronic inflammatory response in atherosclerosis?

<p>Endothelial damage</p> Signup and view all the answers

What causes the endothelium to become leaky in atherosclerosis?

<p>LDL oxidation</p> Signup and view all the answers

What is the role of monocytes in the development of atherosclerosis?

<p>To migrate through the endothelium</p> Signup and view all the answers

What is the main factor that attracts monocytes in the development of atherosclerosis?

<p>Inflammatory response</p> Signup and view all the answers

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