ACS and Atherosclerosis Pathophysiology

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Questions and Answers

Which protein regulates Ca-dependent interactions with myosin in cardiac muscle contraction?

  • Fatty acid-binding protein
  • Myeloperoxidase
  • Myoglobin
  • Troponin (correct)

What is the function of the Z disk in sarcomere structure?

  • Contains myosin filaments
  • Forms a boundary for the sarcomere (correct)
  • Regulates Ca-dependent interactions
  • Promotes cell injury detection

Which enzyme is known to be associated with systemic inflammation after myocardial infarction?

  • Heart-type fatty acid–binding protein
  • Myoglobin
  • C-reactive protein (correct)
  • Ischemia-modified albumin

At what time frame are cardiac troponin levels detectable in the plasma after myocardial injury?

<p>1 to 3 hours (D)</p> Signup and view all the answers

Which protein is used as a marker for cardiac damage but its clinical utility has not been established?

<p>Myoglobin (B)</p> Signup and view all the answers

Which biomarker peaks at 12 to 24 hours after myocardial injury?

<p>Cardiac troponins (B)</p> Signup and view all the answers

In congestive heart failure patients, what was found in their serum according to the text?

<p>Detectable CRP (B)</p> Signup and view all the answers

'Thin filaments' in cardiac muscle contain which of the following proteins?

<p>Actin (C)</p> Signup and view all the answers

What is the main role of cardiac troponin in the immunoassay mentioned in the text?

<p>Detection of myocardial cell injury (B)</p> Signup and view all the answers

What is the characteristic time duration for which TnT and TnI remain elevated after myocardial injury as per the text?

<p>8 to 21 days for TnT, 7 to 14 days for TnI. (A)</p> Signup and view all the answers

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