Atherosclerosis Pathology Overview
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Questions and Answers

What is the main histological feature of atherosclerosis?

  • Collateral circulation
  • Fatty streaks
  • Necrotic center (correct)
  • Lipid-filled foam cells
  • Which diagnostic test can be used to assess the degree of obstruction in arteries?

  • Radioisotopic studies
  • High-sensitivity C-reactive protein levels
  • Serum lipid levels
  • Exercise stress testing (correct)
  • What is the primary function of fibrous caps in atheromatous plaques?

  • Cause local cell metabolism
  • Protrude into vascular lumina
  • Prevent plaque rupture (correct)
  • Form lipid-filled foam cells
  • Which serum levels can indicate the presence of inflammation in a patient with atherosclerosis?

    <p>C-reactive protein levels</p> Signup and view all the answers

    What do fatty streaks represent in the progression of atherosclerosis?

    <p>Not significantly obstructive to blood flow</p> Signup and view all the answers

    Why is monitoring serum lipid levels important in patients with atherosclerosis?

    <p>To monitor treatment efficacy and assess risk</p> Signup and view all the answers

    Study Notes

    Atherosclerosis Characteristics

    • The main histological feature of atherosclerosis is the accumulation of lipids, inflammatory cells, and fibrous tissue in the arterial wall.

    Diagnostic Tests

    • Angiography or Duplex ultrasound can be used to assess the degree of obstruction in arteries.

    Fibrous Caps Function

    • The primary function of fibrous caps in atheromatous plaques is to separate the lipid-rich core from the blood flow and prevent thrombosis.

    Inflammation Indicators

    • Elevated C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) serum levels can indicate the presence of inflammation in a patient with atherosclerosis.

    Atherosclerosis Progression

    • Fatty streaks represent the initial stage of atherosclerosis, characterized by the accumulation of lipids in the arterial wall.

    Lipid Level Monitoring

    • Monitoring serum lipid levels, specifically low-density lipoprotein (LDL) and high-density lipoprotein (HDL) cholesterol, is important in patients with atherosclerosis to assess the risk of cardiovascular events and monitor the effectiveness of lipid-lowering therapy.

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    Description

    Learn about the characteristics and morphology of atherosclerosis, including atheromas, fibrous caps, and fatty streaks. Explore the formation of necrotic centers and cholesterol crystals in atheromas. Important picture descriptions included.

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