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Questions and Answers
What is the main histological feature of atherosclerosis?
What is the main histological feature of atherosclerosis?
- Collateral circulation
- Fatty streaks
- Necrotic center (correct)
- Lipid-filled foam cells
Which diagnostic test can be used to assess the degree of obstruction in arteries?
Which diagnostic test can be used to assess the degree of obstruction in arteries?
- Radioisotopic studies
- High-sensitivity C-reactive protein levels
- Serum lipid levels
- Exercise stress testing (correct)
What is the primary function of fibrous caps in atheromatous plaques?
What is the primary function of fibrous caps in atheromatous plaques?
- Cause local cell metabolism
- Protrude into vascular lumina
- Prevent plaque rupture (correct)
- Form lipid-filled foam cells
Which serum levels can indicate the presence of inflammation in a patient with atherosclerosis?
Which serum levels can indicate the presence of inflammation in a patient with atherosclerosis?
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What do fatty streaks represent in the progression of atherosclerosis?
What do fatty streaks represent in the progression of atherosclerosis?
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Why is monitoring serum lipid levels important in patients with atherosclerosis?
Why is monitoring serum lipid levels important in patients with atherosclerosis?
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Study Notes
Atherosclerosis Characteristics
- The main histological feature of atherosclerosis is the accumulation of lipids, inflammatory cells, and fibrous tissue in the arterial wall.
Diagnostic Tests
- Angiography or Duplex ultrasound can be used to assess the degree of obstruction in arteries.
Fibrous Caps Function
- The primary function of fibrous caps in atheromatous plaques is to separate the lipid-rich core from the blood flow and prevent thrombosis.
Inflammation Indicators
- Elevated C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) serum levels can indicate the presence of inflammation in a patient with atherosclerosis.
Atherosclerosis Progression
- Fatty streaks represent the initial stage of atherosclerosis, characterized by the accumulation of lipids in the arterial wall.
Lipid Level Monitoring
- Monitoring serum lipid levels, specifically low-density lipoprotein (LDL) and high-density lipoprotein (HDL) cholesterol, is important in patients with atherosclerosis to assess the risk of cardiovascular events and monitor the effectiveness of lipid-lowering therapy.
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