Pathology Lecture 1: Arterial Atherosclerosis and Arteriosclerosis

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15 Questions

What is the main characteristic of atherosclerosis?

Patches of intimal thickening and accumulation of lipids

Which risk factor is considered a constitutional (fixed) risk factor for atherosclerosis?

Male gender

What is the pathogenesis of atherosclerosis according to the reaction to injury hypothesis?

Chronic inflammation and healing response due to injury to vessel wall

What is the main characteristic of arteriosclerosis?

Stiffening and loss of elasticity in arteries

Which type of aneurysm involves a tear in the inner layer of the artery wall?

Dissecting aneurysm

What is the composition of fatty streaks in atherosclerosis?

Lipid-filled foamy macrophages

Which vessels are most extensively involved in atherosclerotic lesions?

Coronary arteries and popliteal arteries

What is the main stage of biobodexi in atherosclerosis?

Release of cytokines

What is the characteristic feature of atheromas on cross-sectioning?

Soft, lipid-rich center covered with smooth muscle cells

What is present in the necrotic core of atherosclerotic plaques?

Cholesterol crystals and foam cells

What tissue changes are associated with acute plaque changes in atherosclerosis?

Erosion, ulceration, or rupture

What is the primary cause of the yellow color of atheromas?

Presence of cholesterol crystals and foam cells

What are the earliest recognizable lesions in atherosclerosis?

"Elongated streaks"

What is the characteristic feature of atherosclerotic lesions on cross-sectioning?

"Eccentric" appearance due to patchy lesions

What are the components of a fibrous cap in atherosclerotic plaques?

(Smooth muscle cells, macrophages, foam cells)

Test your knowledge on recognizing arterial atherosclerosis, describing arteriosclerosis and its types, and outlining types of aneurysms and dissection of arteries. This quiz covers the theoretical objectives from CRS 202 Lecture 1 by Dr. Kariman Hussein.

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