Asthma Syndrome Definition Quiz
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Questions and Answers

What is the defining characteristic of asthma according to the provided text?

  • Intermittent narrowing of the bronchi
  • Recurrent and reversible obstruction of the airways (correct)
  • Permanent obstruction of the airways
  • Irreversible narrowing of the bronchioles
  • What is the distribution of bronchial hyperreactivity in the general population?

  • Multimodal
  • Bimodal
  • Normal
  • Unimodal (correct)
  • What mediators are involved in the inflammatory changes in the airways during asthma pathophysiology?

  • Histamine and serotonin
  • Cytokines IL-1 and IL-6
  • Neuropeptides and bradykinin
  • Leukotrienes and PAF (correct)
  • Which cells are recruited to the airways during asthma pathophysiology?

    <p>Mast cells and eosinophils</p> Signup and view all the answers

    What is one common trigger for bronchospasm in individuals with asthma?

    <p>Physical exercise</p> Signup and view all the answers

    What effect does inhalation of an allergen have on airway smooth muscle in individuals with asthma?

    <p>Contraction leading to airway narrowing</p> Signup and view all the answers

    What is the range of heritability percentage in asthma susceptibility studies?

    <p>25-80%</p> Signup and view all the answers

    Which gene was the first to be identified as an asthma susceptibility gene?

    <p>ADAM-33</p> Signup and view all the answers

    Which category of genes are associated with Th2 cell signaling in asthma susceptibility?

    <p>Th2 cell signaling genes</p> Signup and view all the answers

    Which chromosomal location is associated with asthma susceptibility according to GWAS?

    <p>Chr18</p> Signup and view all the answers

    Which factor plays a role in lung development in relation to asthma susceptibility?

    <p>ADAM33</p> Signup and view all the answers

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