Asthma Syndrome Definition Quiz

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Questions and Answers

What is the defining characteristic of asthma according to the provided text?

  • Intermittent narrowing of the bronchi
  • Recurrent and reversible obstruction of the airways (correct)
  • Permanent obstruction of the airways
  • Irreversible narrowing of the bronchioles

What is the distribution of bronchial hyperreactivity in the general population?

  • Multimodal
  • Bimodal
  • Normal
  • Unimodal (correct)

What mediators are involved in the inflammatory changes in the airways during asthma pathophysiology?

  • Histamine and serotonin
  • Cytokines IL-1 and IL-6
  • Neuropeptides and bradykinin
  • Leukotrienes and PAF (correct)

Which cells are recruited to the airways during asthma pathophysiology?

<p>Mast cells and eosinophils (B)</p> Signup and view all the answers

What is one common trigger for bronchospasm in individuals with asthma?

<p>Physical exercise (C)</p> Signup and view all the answers

What effect does inhalation of an allergen have on airway smooth muscle in individuals with asthma?

<p>Contraction leading to airway narrowing (C)</p> Signup and view all the answers

What is the range of heritability percentage in asthma susceptibility studies?

<p>25-80% (B)</p> Signup and view all the answers

Which gene was the first to be identified as an asthma susceptibility gene?

<p>ADAM-33 (C)</p> Signup and view all the answers

Which category of genes are associated with Th2 cell signaling in asthma susceptibility?

<p>Th2 cell signaling genes (D)</p> Signup and view all the answers

Which chromosomal location is associated with asthma susceptibility according to GWAS?

<p>Chr18 (D)</p> Signup and view all the answers

Which factor plays a role in lung development in relation to asthma susceptibility?

<p>ADAM33 (C)</p> Signup and view all the answers

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