Ascomycete Yeasts and Mating-Type Switching
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Questions and Answers

What mechanism allows pathogens to evade the host's immune system?

  • Break-Induced Replication (BIR)
  • Single-Strand Annealing (SSA)
  • Antigenic variation (correct)
  • Non-homologous End-Joining (NHEJ)

How does the yeast mating-type switch differ from common gene regulation mechanisms?

  • It does not involve homologous recombination.
  • It involves the expression of multiple genes at once.
  • It is a slower process than common gene regulation mechanisms.
  • It allows for switching between distinct sets of genes. (correct)

How does the DNA double-strand break (DSB) occur in the yeast mating-type switch?

  • It is not known how it occurs.
  • It is induced by a protein called Ho. (correct)
  • It occurs spontaneously.
  • It is caused by radiation.

Which of the following is NOT a model for homologous recombination (HR)?

<p>Non-homologous End-Joining (NHEJ) (A)</p> Signup and view all the answers

What is the role of the silent loci HMR and HML in the yeast mating-type switch?

<p>They provide the genetic material to replace the original MAT sequence. (B)</p> Signup and view all the answers

What is the main advantage of the absolute switch between the 'a' and 'alpha' states in yeast?

<p>It prevents leaked expression of the wrong genes. (C)</p> Signup and view all the answers

What genetic feature allows haploid yeast cells to create cells of the opposite mating type?

<p>The mating-type switching process (B)</p> Signup and view all the answers

What is the preferred state of yeast cells in the wild-type?

<p>Diploidy (A)</p> Signup and view all the answers

Which of the following components is not involved in the mating-type switching system?

<p>Chromosomal double-strand break (DSB) repair mechanism (A)</p> Signup and view all the answers

Why are laboratory strains of yeast mutant for Ho easier to isolate and maintain?

<p>Because they are unable to undergo mating-type switching (D)</p> Signup and view all the answers

What is the mating type locus (MAT) responsible for in yeast cells?

<p>Differentiating the two mating types in haploid cells (B)</p> Signup and view all the answers

Which of the following statements about the model yeast Saccharomyces cerevisiae is true?

<p>It is either diploid or polyploid in the wild (D)</p> Signup and view all the answers

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