12 Questions
What mechanism allows pathogens to evade the host's immune system?
Antigenic variation
How does the yeast mating-type switch differ from common gene regulation mechanisms?
It allows for switching between distinct sets of genes.
How does the DNA double-strand break (DSB) occur in the yeast mating-type switch?
It is induced by a protein called Ho.
Which of the following is NOT a model for homologous recombination (HR)?
Non-homologous End-Joining (NHEJ)
What is the role of the silent loci HMR and HML in the yeast mating-type switch?
They provide the genetic material to replace the original MAT sequence.
What is the main advantage of the absolute switch between the 'a' and 'alpha' states in yeast?
It prevents leaked expression of the wrong genes.
What genetic feature allows haploid yeast cells to create cells of the opposite mating type?
The mating-type switching process
What is the preferred state of yeast cells in the wild-type?
Diploidy
Which of the following components is not involved in the mating-type switching system?
Chromosomal double-strand break (DSB) repair mechanism
Why are laboratory strains of yeast mutant for Ho easier to isolate and maintain?
Because they are unable to undergo mating-type switching
What is the mating type locus (MAT) responsible for in yeast cells?
Differentiating the two mating types in haploid cells
Which of the following statements about the model yeast Saccharomyces cerevisiae is true?
It is either diploid or polyploid in the wild
Learn about the unique mating behaviors of Ascomycete yeasts, where haploid cells express different mating types MATa and MATalpha, while diploid cells express both. Explore the process of mating-type switching and how it allows haploid yeast cells to create cells of the other mating type.
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