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Ascomycete Yeasts and Mating-Type Switching

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Ascomycete Yeasts and Mating-Type Switching

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Questions and Answers

What mechanism allows pathogens to evade the host's immune system?

Break-Induced Replication (BIR)

Single-Strand Annealing (SSA)

Antigenic variation (correct)

Non-homologous End-Joining (NHEJ)

How does the yeast mating-type switch differ from common gene regulation mechanisms?

It does not involve homologous recombination.

It involves the expression of multiple genes at once.

It is a slower process than common gene regulation mechanisms.

It allows for switching between distinct sets of genes. (correct)

How does the DNA double-strand break (DSB) occur in the yeast mating-type switch?

It is not known how it occurs.

It is induced by a protein called Ho. (correct)

It occurs spontaneously.

It is caused by radiation.

Which of the following is NOT a model for homologous recombination (HR)?

Non-homologous End-Joining (NHEJ) Signup and view all the answers

What is the role of the silent loci HMR and HML in the yeast mating-type switch?

They provide the genetic material to replace the original MAT sequence. Signup and view all the answers

What is the main advantage of the absolute switch between the 'a' and 'alpha' states in yeast?

It prevents leaked expression of the wrong genes. Signup and view all the answers

What genetic feature allows haploid yeast cells to create cells of the opposite mating type?

The mating-type switching process Signup and view all the answers

What is the preferred state of yeast cells in the wild-type?

Diploidy Signup and view all the answers

Which of the following components is not involved in the mating-type switching system?

Chromosomal double-strand break (DSB) repair mechanism Signup and view all the answers

Why are laboratory strains of yeast mutant for Ho easier to isolate and maintain?

Because they are unable to undergo mating-type switching Signup and view all the answers

What is the mating type locus (MAT) responsible for in yeast cells?

Differentiating the two mating types in haploid cells Signup and view all the answers

Which of the following statements about the model yeast Saccharomyces cerevisiae is true?

It is either diploid or polyploid in the wild Signup and view all the answers