Arsenic Compounds and Their Uses
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Arsenic Compounds and Their Uses

This quiz covers the properties and uses of arsenic compounds, including arsenious oxide and copper arsenite, in various industries such as agriculture, manufacturing, and more.

Created by
@AgileBohrium

Questions and Answers

In which tissue is arsenic present in the greatest quantity?

Liver

What is the typical appearance of stool in acute arsenic poisoning?

Rice-water like, colorless, and odorless

Which of the following symptoms is NOT typical of acute arsenic poisoning?

Seizures

In what time frame do symptoms of acute arsenic poisoning typically appear?

<p>Within 1 hour</p> Signup and view all the answers

What is the primary use of arsenic trioxide?

<p>Insecticides and rat poisons</p> Signup and view all the answers

Which of the following is a natural source of arsenic?

<p>Some sea fish</p> Signup and view all the answers

Study Notes

Arsenic Compounds

  • Arsenious oxide (arsenic trioxide) is the most toxic form of arsenic, with no taste or smell, and is sparingly soluble in water.
  • It is used in fruit sprays, sheep-dips, weed-killers, insecticides, rat poisons, flypapers, calico-printing, wallpapers, and as a mordant in dyeing.

Copper Arsenite and Copper Acetoarsenite

  • Copper arsenite (Scheele's green) and copper acetoarsenite (Paris green or emerald green) are used as coloring agents in substances, including confectionary.

Arsenic Sulphide and Arsine

  • Arsenic sulphide is used as a depilatory, coloring pigment, and in flypaper.
  • Arsine is a colorless gas with a garlic-like odor.

Natural Sources of Arsenic

  • Arsenic can be found naturally in soil, water, and some sea fish (mussels, prawns).
  • High arsenic content in soil and subsoil water can cause endemic toxicity.

Action of Arsenic

  • Arsenic interferes with cellular respiration by uncoupling mitochondrial oxidative phosphorylation.
  • It combines with sulfhydryl groups of mitochondrial enzymes, inhibiting cellular glucose uptake, gluconeogenesis, fatty acid oxidation, and acetyl CoA production.
  • Locally, arsenic causes irritation of mucous membranes, and remotely, depression of the nervous system.

Carcinogenic Effects of Arsenic

  • Arsenic is a carcinogenic substance linked to lung, skin, and bladder carcinoma in populations with multiple exposures.

Absorption and Excretion of Arsenic

  • Arsenic is absorbed orally through the GIT, skin, and lungs, and can also be absorbed parenterally.
  • It is present in almost all tissues, with the highest concentration found in the liver, kidneys, and spleen.
  • Arsenic is excreted mainly by the kidneys, but also through feces, bile, sweat, milk, nails, and hair.

Signs and Symptoms of Acute Poisoning

  • Symptoms usually appear within 1 hour of ingestion, but may be delayed if arsenic is taken with food.
  • GIT symptoms include sweet metallic taste, nausea, persistent vomiting, burning in the mouth and throat, difficulty in swallowing, and garlic odor in breath.
  • Other symptoms include intense thirst, pain in the esophagus and abdomen, purging accompanied by tenesmus, and pain and irritation around the anus.
  • Renal symptoms include oliguria, uremia, albuminuria, red cells, and casts, as well as pain during micturition.
  • CVS symptoms include hypotension, circulatory collapse, ventricular tachycardia, and fibrillation.
  • Hepatic symptom includes fatty infiltration.
  • MS symptoms include pain in limbs and weakness.
  • CNS symptoms include headache, vertigo, and hyperthermia.

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