Arsenic Poisoning in Animals

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Questions and Answers

What are the common symptoms of arsenic poisoning in animals?

  • Fever and coughing
  • Intense abdominal pain and staggering gait (correct)
  • Loss of appetite and excessive urination
  • Skin rash and headache

What are the recommended treatments for arsenic poisoning in companion animals?

  • Administering painkillers and providing a high-protein diet
  • Emesis or gastric emptying, if possible, and administering charcoal (correct)
  • Administering charcoal and avoiding water intake
  • Using antibiotics and isolating the animal

Which species is most sensitive to single, lethal doses of inorganic trivalent arsenicals?

  • Horses
  • Birds
  • Cattle
  • Cats (correct)

What makes trivalent arsenicals more toxic than pentavalent compounds?

<p>They are more soluble (C)</p> Signup and view all the answers

What is the recommended treatment for animals with recent exposure to arsenic and no clinical signs of toxicosis?

<p>Emesis followed by activated charcoal with a cathartic, and then oral administration of demulcents (D)</p> Signup and view all the answers

What is the recommended treatment for animals already showing clinical signs of arsenic toxicosis?

<p>Aggressive fluid therapy, blood transfusion (if needed), and administration of dimercaprol (B)</p> Signup and view all the answers

What is the suggested treatment specifically for large animals in arsenic toxicosis?

<p>Use of thioctic acid alone or in combination with dimercaprol (B)</p> Signup and view all the answers

Which is considered to be less toxic and more effective for oral administration in animals with arsenic toxicosis?

<p>Sodium thiosulfate (D)</p> Signup and view all the answers

What should be monitored during treatment of animals with inorganic arsenical toxicosis?

<p>Kidney and liver function (B)</p> Signup and view all the answers

When should inorganic arsenical toxicosis be considered in animals?

<p>When there is intense abdominal pain and mucoid diarrhea (D)</p> Signup and view all the answers

What is the primary cause of the profuse watery diarrhea in inorganic arsenical toxicosis?

<p>Damage to microvascular integrity (C)</p> Signup and view all the answers

Which of the following organs shows the highest levels of arsenic distribution after absorption?

<p>Liver (D)</p> Signup and view all the answers

In what form is most of the absorbed arsenic excreted in the urine?

<p>Inorganic arsenic (B)</p> Signup and view all the answers

What is the main target of arsenic damage in tissues vulnerable to toxicity?

<p>Oxidative enzymes (D)</p> Signup and view all the answers

What is a characteristic feature of peracute inorganic arsenical toxicosis in animals?

<p>Perforation of the gastric wall (D)</p> Signup and view all the answers

Which diagnostic method is generally used for confirming the presence of inorganic arsenic in suspected cases of poisoning?

<p>Chemical testing of stomach contents or tissue samples (A)</p> Signup and view all the answers

What is the main mechanism through which trivalent inorganic and aliphatic organic arsenic compounds exert their toxicity?

<p>Interaction with sulfhydryl enzymes (D)</p> Signup and view all the answers

What is the characteristic feature of poisoning by soluble forms of arsenic compounds?

<p>Necrosis and dryness of the skin (A)</p> Signup and view all the answers

Which organ exhibits characteristic hyperemic lesions known as 'paintbrush lesions' in ruminants with inorganic arsenical toxicosis?

<p>Omasum (B)</p> Signup and view all the answers

What concentration of arsenic in drinking water is considered potentially toxic for large animals?

<p>0.25 ppm (B)</p> Signup and view all the answers

What is the primary cause of death in peracute poisoning by inorganic arsenical compounds?

<p>Cardiovascular collapse (B)</p> Signup and view all the answers

What concentration of arsenic in tissues is associated with toxicity?

<p>3 ppm (wet weight) (C)</p> Signup and view all the answers

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