Arsenic Poisoning in Animals
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Arsenic Poisoning in Animals

Test your knowledge about the symptoms, diagnosis, and treatment of arsenic poisoning in animals caused by inorganic arsenic compounds such as arsenite or arsenate. Learn about the clinical signs and diagnostic procedures for evaluating suspected cases.

Created by
@HopefulSage

Questions and Answers

What are the common symptoms of arsenic poisoning in animals?

Intense abdominal pain and staggering gait

What are the recommended treatments for arsenic poisoning in companion animals?

Emesis or gastric emptying, if possible, and administering charcoal

Which species is most sensitive to single, lethal doses of inorganic trivalent arsenicals?

Cats

What makes trivalent arsenicals more toxic than pentavalent compounds?

<p>They are more soluble</p> Signup and view all the answers

What is the recommended treatment for animals with recent exposure to arsenic and no clinical signs of toxicosis?

<p>Emesis followed by activated charcoal with a cathartic, and then oral administration of demulcents</p> Signup and view all the answers

What is the recommended treatment for animals already showing clinical signs of arsenic toxicosis?

<p>Aggressive fluid therapy, blood transfusion (if needed), and administration of dimercaprol</p> Signup and view all the answers

What is the suggested treatment specifically for large animals in arsenic toxicosis?

<p>Use of thioctic acid alone or in combination with dimercaprol</p> Signup and view all the answers

Which is considered to be less toxic and more effective for oral administration in animals with arsenic toxicosis?

<p>Sodium thiosulfate</p> Signup and view all the answers

What should be monitored during treatment of animals with inorganic arsenical toxicosis?

<p>Kidney and liver function</p> Signup and view all the answers

When should inorganic arsenical toxicosis be considered in animals?

<p>When there is intense abdominal pain and mucoid diarrhea</p> Signup and view all the answers

What is the primary cause of the profuse watery diarrhea in inorganic arsenical toxicosis?

<p>Damage to microvascular integrity</p> Signup and view all the answers

Which of the following organs shows the highest levels of arsenic distribution after absorption?

<p>Liver</p> Signup and view all the answers

In what form is most of the absorbed arsenic excreted in the urine?

<p>Inorganic arsenic</p> Signup and view all the answers

What is the main target of arsenic damage in tissues vulnerable to toxicity?

<p>Oxidative enzymes</p> Signup and view all the answers

What is a characteristic feature of peracute inorganic arsenical toxicosis in animals?

<p>Perforation of the gastric wall</p> Signup and view all the answers

Which diagnostic method is generally used for confirming the presence of inorganic arsenic in suspected cases of poisoning?

<p>Chemical testing of stomach contents or tissue samples</p> Signup and view all the answers

What is the main mechanism through which trivalent inorganic and aliphatic organic arsenic compounds exert their toxicity?

<p>Interaction with sulfhydryl enzymes</p> Signup and view all the answers

What is the characteristic feature of poisoning by soluble forms of arsenic compounds?

<p>Necrosis and dryness of the skin</p> Signup and view all the answers

Which organ exhibits characteristic hyperemic lesions known as 'paintbrush lesions' in ruminants with inorganic arsenical toxicosis?

<p>Omasum</p> Signup and view all the answers

What concentration of arsenic in drinking water is considered potentially toxic for large animals?

<p>0.25 ppm</p> Signup and view all the answers

What is the primary cause of death in peracute poisoning by inorganic arsenical compounds?

<p>Cardiovascular collapse</p> Signup and view all the answers

What concentration of arsenic in tissues is associated with toxicity?

<p>3 ppm (wet weight)</p> Signup and view all the answers

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