Podcast
Questions and Answers
What condition is strongly suggested when a person has four or more of the diagnostic criteria?
What condition is strongly suggested when a person has four or more of the diagnostic criteria?
- Systemic Lupus Erythematosus (SLE) (correct)
- Psoriasis
- Rheumatoid Arthritis
- Multiple Sclerosis
Fatigue is a clear and specific diagnostic criterion for SLE.
Fatigue is a clear and specific diagnostic criterion for SLE.
False (B)
What is a common symptom of SLE that appears as a rash over the cheeks?
What is a common symptom of SLE that appears as a rash over the cheeks?
Malar rash
What type of skin lesion is characterized by being rough, scaly, raised, and red circular?
What type of skin lesion is characterized by being rough, scaly, raised, and red circular?
SLE might involve ___________ of the serous membranes lining the lungs.
SLE might involve ___________ of the serous membranes lining the lungs.
What is the medical term for joint inflammation that causes pain and swelling in SLE?
What is the medical term for joint inflammation that causes pain and swelling in SLE?
What term describes the lower white blood cell count observed in some SLE patients?
What term describes the lower white blood cell count observed in some SLE patients?
What is suggested when a person has four or more criteria for SLE?
What is suggested when a person has four or more criteria for SLE?
What does the term 'malar rash' refer to?
What does the term 'malar rash' refer to?
Oral ulcers in SLE can resemble cold sores.
Oral ulcers in SLE can resemble cold sores.
Which of the following is NOT a clinical criterion for SLE diagnosis?
Which of the following is NOT a clinical criterion for SLE diagnosis?
In SLE, joint inflammation is referred to as ______.
In SLE, joint inflammation is referred to as ______.
What type of inflammation does serositis refer to?
What type of inflammation does serositis refer to?
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Study Notes
Systemic Lupus Erythematosus (SLE) Diagnosis
- SLE criteria are continually updated, aiming for universal consensus on diagnosis.
- Some patients may never meet the full diagnostic criteria for SLE, while others may take years to accumulate enough symptoms for a confirmed diagnosis.
- A strong suggestion of SLE arises when a patient presents with four or more criteria.
- Symptoms of SLE can overlap with other disorders, making diagnosis challenging.
Clinical Criteria for SLE Diagnosis
- Skin Manifestations: Acute/subacute cutaneous involvement includes a malar rash (butterfly rash), photosensitivity, and chronic cutaneous lesions such as discoid lupus (characterized by rough, scaly, raised red circles).
- Oral Lesions: Presence of oral ulcers resembling aphthous ulcers, which can also appear in the nasal area.
- Hair Loss: Alopecia typically presents as patchy thinning.
- Joint Inflammation: Synovitis leads to pain and swelling, typically symmetric, affecting two or more joints, potentially migrating in location.
- Serositis: Involves inflammation of serous membranes lining the lungs (pleura), heart (pericardium), and inner abdomen (peritoneum).
- Hematological Changes: Includes hemolytic anemia and leukopenia.
Systemic Lupus Erythematosus (SLE) Diagnosis
- SLE criteria are continually updated, aiming for universal consensus on diagnosis.
- Some patients may never meet the full diagnostic criteria for SLE, while others may take years to accumulate enough symptoms for a confirmed diagnosis.
- A strong suggestion of SLE arises when a patient presents with four or more criteria.
- Symptoms of SLE can overlap with other disorders, making diagnosis challenging.
Clinical Criteria for SLE Diagnosis
- Skin Manifestations: Acute/subacute cutaneous involvement includes a malar rash (butterfly rash), photosensitivity, and chronic cutaneous lesions such as discoid lupus (characterized by rough, scaly, raised red circles).
- Oral Lesions: Presence of oral ulcers resembling aphthous ulcers, which can also appear in the nasal area.
- Hair Loss: Alopecia typically presents as patchy thinning.
- Joint Inflammation: Synovitis leads to pain and swelling, typically symmetric, affecting two or more joints, potentially migrating in location.
- Serositis: Involves inflammation of serous membranes lining the lungs (pleura), heart (pericardium), and inner abdomen (peritoneum).
- Hematological Changes: Includes hemolytic anemia and leukopenia.
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