5 Questions
What is the role of CAD in DNA fragmentation during apoptosis?
CAD cuts the chromosomal DNA between nucleosomes
What happens to iCAD during apoptosis?
iCAD is cleaved by executioner caspases
What is the result of DNA fragmentation during apoptosis on gel electrophoresis?
Formation of a ladder pattern
Why are smaller molecules more widely separated in the lower part of the gel during electrophoresis?
To show a greater apparent effect on gel mobility
How are apoptotic nuclei detected in the image shown in the text?
By adding a fluorescent label to DNA ends
Test your knowledge of DNA fragmentation during apoptosis with this quiz. Explore the process of CAD activation and its role in producing DNA fragments, which form a distinct ladder pattern on gel electrophoresis. Delve into the molecular mechanisms underlying this essential aspect of programmed cell death.
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