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Questions and Answers
What is the role of CAD in DNA fragmentation during apoptosis?
What is the role of CAD in DNA fragmentation during apoptosis?
- CAD cuts the chromosomal DNA between nucleosomes (correct)
- CAD inhibits the production of DNA fragments
- CAD activates the executioner caspases
- CAD stabilizes the iCAD inhibitor
What happens to iCAD during apoptosis?
What happens to iCAD during apoptosis?
- iCAD is cleaved by executioner caspases (correct)
- iCAD activates DNA fragmentation
- iCAD stabilizes the chromosomal DNA
- iCAD inhibits CAD activity
What is the result of DNA fragmentation during apoptosis on gel electrophoresis?
What is the result of DNA fragmentation during apoptosis on gel electrophoresis?
- Formation of a single band
- Formation of a ladder pattern (correct)
- Formation of a random pattern
- No change in the DNA pattern
Why are smaller molecules more widely separated in the lower part of the gel during electrophoresis?
Why are smaller molecules more widely separated in the lower part of the gel during electrophoresis?
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How are apoptotic nuclei detected in the image shown in the text?
How are apoptotic nuclei detected in the image shown in the text?
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