Podcast
Questions and Answers
Which class of drugs slows down the protein synthesis and transcription of viral mRNA in an infected cell?
Which class of drugs slows down the protein synthesis and transcription of viral mRNA in an infected cell?
What is the main target of protease inhibitors like Boceprevir and telaprevir?
What is the main target of protease inhibitors like Boceprevir and telaprevir?
Which enzyme of influenza viruses is crucial in preventing intracellular and cell surface aggregation of viral glycoproteins?
Which enzyme of influenza viruses is crucial in preventing intracellular and cell surface aggregation of viral glycoproteins?
What is the primary mechanism of action of lamivudine and adefovir in inhibiting viral replication?
What is the primary mechanism of action of lamivudine and adefovir in inhibiting viral replication?
Signup and view all the answers
Which drug class targets specific posttranslational modifications of viral proteins?
Which drug class targets specific posttranslational modifications of viral proteins?
Signup and view all the answers
Which of the following drugs is a guanosine analog that causes premature DNA chain termination?
Which of the following drugs is a guanosine analog that causes premature DNA chain termination?
Signup and view all the answers
How do amantadine and rimantadine inhibit viral replication?
How do amantadine and rimantadine inhibit viral replication?
Signup and view all the answers
Which drug is effective against many RNA viruses, including respiratory syncytial virus infections in infants?
Which drug is effective against many RNA viruses, including respiratory syncytial virus infections in infants?
Signup and view all the answers
What is the mechanism of action of ribavirin in inhibiting viral replication?
What is the mechanism of action of ribavirin in inhibiting viral replication?
Signup and view all the answers
Which of the following drugs is converted into di- and triphosphate forms by host cell kinases to cause premature DNA chain termination?
Which of the following drugs is converted into di- and triphosphate forms by host cell kinases to cause premature DNA chain termination?
Signup and view all the answers
What is the mechanism of action of ribavirin 5`-phosphate derivatives?
What is the mechanism of action of ribavirin 5`-phosphate derivatives?
Signup and view all the answers
Which type of viruses can be targeted by reverse transcriptase inhibitors?
Which type of viruses can be targeted by reverse transcriptase inhibitors?
Signup and view all the answers
What is the role of Remdesivir as an antiviral agent?
What is the role of Remdesivir as an antiviral agent?
Signup and view all the answers
Why are reverse transcriptase inhibitors phosphorylated to the active form by host kinases?
Why are reverse transcriptase inhibitors phosphorylated to the active form by host kinases?
Signup and view all the answers
When is Remdesivir currently approved as a COVID-19 treatment?
When is Remdesivir currently approved as a COVID-19 treatment?
Signup and view all the answers
What is the first step in the viral life cycle?
What is the first step in the viral life cycle?
Signup and view all the answers
Which type of antibodies bind to the viral attachment protein to prevent viral entry into cells?
Which type of antibodies bind to the viral attachment protein to prevent viral entry into cells?
Signup and view all the answers
What is a common mechanism of inhibitors that target viral uncoating?
What is a common mechanism of inhibitors that target viral uncoating?
Signup and view all the answers
Which type of antiviral therapy involves the administration of specific antibodies?
Which type of antiviral therapy involves the administration of specific antibodies?
Signup and view all the answers
For viruses that enter through endocytic vesicles, which process can be disrupted by inhibitors of viral uncoating?
For viruses that enter through endocytic vesicles, which process can be disrupted by inhibitors of viral uncoating?
Signup and view all the answers
