Antiviral Medications Mechanisms Quiz
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Questions and Answers

Which class of drugs slows down the protein synthesis and transcription of viral mRNA in an infected cell?

  • Interferon (correct)
  • Polymerase inhibitors
  • Neuraminidase inhibitors
  • Protease inhibitors

What is the main target of protease inhibitors like Boceprevir and telaprevir?

  • Viral mRNA splicing
  • Viral genome replication
  • Viral-specific posttranslational modifications (correct)
  • Viral glycoproteins

Which enzyme of influenza viruses is crucial in preventing intracellular and cell surface aggregation of viral glycoproteins?

  • RNA polymerase
  • Neuraminidase (correct)
  • Reverse transcriptase
  • Helicase

What is the primary mechanism of action of lamivudine and adefovir in inhibiting viral replication?

<p>Slowing down protein synthesis and transcription of viral mRNA (C)</p> Signup and view all the answers

Which drug class targets specific posttranslational modifications of viral proteins?

<p>Protease inhibitors (B)</p> Signup and view all the answers

Which of the following drugs is a guanosine analog that causes premature DNA chain termination?

<p>Acyclovir (D)</p> Signup and view all the answers

How do amantadine and rimantadine inhibit viral replication?

<p>By blocking the hydrogen channel formed by the viral M2 proton pore (C)</p> Signup and view all the answers

Which drug is effective against many RNA viruses, including respiratory syncytial virus infections in infants?

<p>Ribavirin (D)</p> Signup and view all the answers

What is the mechanism of action of ribavirin in inhibiting viral replication?

<p>Inhibiting GTP formation (A)</p> Signup and view all the answers

Which of the following drugs is converted into di- and triphosphate forms by host cell kinases to cause premature DNA chain termination?

<p>Valacyclovir (A)</p> Signup and view all the answers

What is the mechanism of action of ribavirin 5`-phosphate derivatives?

<p>Inhibit viral RNA polymerase (A)</p> Signup and view all the answers

Which type of viruses can be targeted by reverse transcriptase inhibitors?

<p>Retroviruses (D)</p> Signup and view all the answers

What is the role of Remdesivir as an antiviral agent?

<p>Inhibits viral RNA polymerase (D)</p> Signup and view all the answers

Why are reverse transcriptase inhibitors phosphorylated to the active form by host kinases?

<p>To inhibit viral reverse transcriptase (A)</p> Signup and view all the answers

When is Remdesivir currently approved as a COVID-19 treatment?

<p>Within 5 days of symptoms (C)</p> Signup and view all the answers

What is the first step in the viral life cycle?

<p>Viral attachment to the cell (B)</p> Signup and view all the answers

Which type of antibodies bind to the viral attachment protein to prevent viral entry into cells?

<p>Neutralizing antibodies (B)</p> Signup and view all the answers

What is a common mechanism of inhibitors that target viral uncoating?

<p>Interfering with disassembly of capsid (A)</p> Signup and view all the answers

Which type of antiviral therapy involves the administration of specific antibodies?

<p>Immunotherapy (D)</p> Signup and view all the answers

For viruses that enter through endocytic vesicles, which process can be disrupted by inhibitors of viral uncoating?

<p>Interaction with fusion protein (A)</p> Signup and view all the answers

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