24 Questions
Which of the following is true about chlorhexidine gluconate (Hibiclens)?
It is effective against GPCs, GNRs, and fungi
Which antibiotic inhibits DNA helicase (DNA gyrase)?
Quinolones
What is the mechanism of action of metronidazole (Flagyl)?
Production of oxygen radicals that breakup DNA
What is the mechanism of action of sulfonamides?
PABA analogue, inhibits purine synthesis
Which type of antibiotics have irreversible binding to ribosome and are considered bactericidal?
Aminoglycosides
What is the most common method of antibiotic resistance?
Transfer of plasmids
What is the mechanism of action of penicillins?
Inhibition of cell wall synthesis
What type of antibiotics are tetracycline, clindamycin, and erythromycin?
Bacteriostatic antibiotics with irreversible ribosomal binding
Which antibiotic produces oxygen radicals that break up DNA?
Metronidazole (Flagyl)
Which antibiotic inhibits RNA polymerase?
Rifampin
What is the mechanism of action of trimethoprim?
Inhibition of dihydrofolate reductase, which inhibits purine synthesis
What antibiotic is effective against GPCs and GNRs but poor for fungi?
Iodophors (Betadine)
What is the specific antibiotic effective for enterococci but not effective for Pseudomonas, Acinetobacter, or Serratia?
Ampicillin
Which drug has a side effect of inhibiting platelets and has a high salt load?
Timentin (ticarcillin/clavulanic acid)
Which antibiotic has the longest half-life and is therefore best for prophylaxis?
Cefotetan
Which antipseudomonal penicillin is effective for enterococci and Pseudomonas, Acinetobacter, and Serratia?
Zosyn (piperacillin/tazobactam)
Which antibiotic is not effective for MEP: MRSA, Enterococcus, and Proteus?
Carbapenems (meropenem, imipenem)
Which antibiotic facilitates aminoglycoside penetration and has the side effects of reversible nephrotoxicity and irreversible ototoxicity?
Beta-lactams (ampicillin, amoxicillin)
Which antifungal drug binds ergosterols in the wall and alters membrane permeability?
Amphotericin
Which antituberculosis drug inhibits RNA polymerase?
Rifampin
Which antiviral drug is used for CMV infections and has the side effects of decreased bone marrow and CNS toxicity?
Ganciclovir
What is the side effect of hepatotoxicity associated with which antituberculosis drug?
Isoniazid
Which antiviral drug is used for HSV infections and EBV?
Acyclovir
What side effect is associated with erythromycin (macrolides)?
Nausea (PO), cholestasis (IV)
Test your knowledge of antiseptics, disinfectants, and antibiotics with this quiz. Learn about the different types of antiseptics used in surgery and the mechanism of action of various antibiotics.
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