Antimicrobial Agents: Vancomycin Mechanism of Action

Play an AI-generated podcast conversation about this lesson

What is the mechanism of action of chloramphenicol?

Inhibiting DNA gyrase

Inhibiting cell wall synthesis

Inhibiting protein synthesis by binding to the 50S ribosomal subunit (correct)

Inhibiting dihydropteroate synthase

What is the most serious adverse effect of chloramphenicol in humans?

Abdominal distention

Allergic reactions

Bone marrow suppression and aplastic anemia (correct)

Gray baby syndrome

What is the clinical use of sulfa drugs?

Treating fungal infections

Treating bacterial infections such as urinary tract infections (correct)

Treating parasitic infections

Treating viral infections

What is the mechanism of action of sulfa drugs?

Inhibiting dihydropteroate synthase Signup and view all the answers

Why are sulfonamides not classified as antibiotics?

Because they are not produced by living organisms Signup and view all the answers

What is the potential side effect of taking sulfa drugs for a long period of time?

Blood problems Signup and view all the answers

What is the mechanism of action of vancomycin?

Inhibits bacterial cell wall synthesis Signup and view all the answers

Which type of bacteria is vancomycin used to treat?

Gram-positive bacteria Signup and view all the answers

What is a potential side effect of vancomycin administration?

Red neck syndrome Signup and view all the answers

What is a clinical use of vancomycin?

Pseudomembranous colitis Signup and view all the answers

What is a potential toxicity of aminoglycosides?

Ototoxicity Signup and view all the answers

What is an indication for chloramphenicol use?

Bacterial conjunctivitis Signup and view all the answers

What is a potential consequence of having low blood counts due to sulfonamides?

Delayed healing of gum bleeds Signup and view all the answers

What is the primary route of administration for quinolones?

Oral Signup and view all the answers

Which of the following antibiotics is bactericidal?

Quinolones Signup and view all the answers

What is a potential adverse effect of taking sulfonamides?

Sun sensitivity Signup and view all the answers

Why should dental work be postponed when taking sulfonamides?

Until blood counts return to normal Signup and view all the answers

What is a characteristic of fluoroquinolones?

They are generally very safe Signup and view all the answers