Antimicrobial Agents Mechanisms and Interactions

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Questions and Answers

What is the main function of folic acid synthesis in bacterial and mammalian cells?

  • Essential for nucleotide synthesis (correct)
  • Aids in cell division
  • Facilitates ATP production
  • Promotes protein synthesis

How do tetracyclines primarily enter bacterial cells?

  • Simple diffusion
  • Endocytosis
  • Facilitated diffusion
  • Active transport via ATP-dependent system (correct)

What characteristic of doxycycline and minocycline makes them more preferable than tetracycline and oxytetracycline?

  • Higher protein binding
  • Less absorption interference from food (correct)
  • Increased renal excretion
  • Greater activity against staphylococcus species

Which type of excretion is common for tetracyclines like doxycycline and minocycline?

<p>Renal excretion (A)</p> Signup and view all the answers

How are sulfamethoxazole and trimethoprim (SMZ-TMP) classified in terms of their effect on bacterial species?

<p>Synergistic (C)</p> Signup and view all the answers

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