Podcast
Questions and Answers
Which type of antibiotic affects a wide range of bacteria, including both Gram-positive and Gram-negative?
Which type of antibiotic affects a wide range of bacteria, including both Gram-positive and Gram-negative?
- Chemotherapeutic agent
- Antimicrobial chemotherapy
- Broad spectrum antibiotic (correct)
- Narrow spectrum antibiotic
Which class of antibiotics includes agents that inhibit cell wall synthesis?
Which class of antibiotics includes agents that inhibit cell wall synthesis?
- Penicillins
- Drug Target Sites
- β-Lactams (correct)
- Antibiotic Attributes of an Ideal Antimicrobial Agent
What are the general properties of ideal antimicrobial agents?
What are the general properties of ideal antimicrobial agents?
- Highly effective against a broad spectrum of pathogens, low toxicity, and minimal side effects (correct)
- Effective against both bacteria and viruses, high toxicity, and minimal side effects
- Only effective against Gram-positive bacteria, low toxicity, and minimal side effects
- Effective against specific pathogens, high toxicity, and significant side effects
Which type of penicillin is less acid labile and can be taken orally?
Which type of penicillin is less acid labile and can be taken orally?
Which salt of benzylpenicillin is used for prolonged action via intramuscular administration?
Which salt of benzylpenicillin is used for prolonged action via intramuscular administration?
Why is benzylpenicillin effective against a narrow spectrum of bacteria?
Why is benzylpenicillin effective against a narrow spectrum of bacteria?
Flashcards
Broad-spectrum antibiotic
Broad-spectrum antibiotic
Affects a wide range of bacteria, including both Gram-positive and Gram-negative.
Beta-Lactams
Beta-Lactams
A class of antibiotics that inhibits cell wall synthesis in bacteria.
Ideal antimicrobial agent properties
Ideal antimicrobial agent properties
Highly effective against pathogens, low toxicity, minimal side effects.
Penicillin-V
Penicillin-V
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Benzathine benzylpenicillin
Benzathine benzylpenicillin
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Benzylpenicillin's narrow spectrum
Benzylpenicillin's narrow spectrum
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Study Notes
Types of Antibiotics
- Broad-spectrum antibiotics target a wide range of bacteria, including both Gram-positive and Gram-negative types.
Antibiotic Classes
- Beta-lactam antibiotics include agents that inhibit cell wall synthesis, crucial for bacterial structural integrity.
Ideal Antimicrobial Properties
- Ideally, antimicrobial agents should have a selective toxicity, minimal side effects on host, effective against pathogens, stability in body fluids, and an ability to penetrate tissues.
Penicillin Types
- Penicillin V is less acid labile, allowing for oral administration without significant degradation.
Benzylpenicillin Administration
- Benzylpenicillin procaine salt is used for prolonged action through intramuscular administration, enhancing the antibiotic’s duration in the system.
Spectrum of Benzylpenicillin
- Benzylpenicillin is effective against a narrow spectrum of bacteria due to its specific mechanism targeting mainly Gram-positive organisms and a select few Gram-negative bacteria.
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