Antimicrobial Agents Quiz

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Questions and Answers

Which type of antibiotic affects a wide range of bacteria, including both Gram-positive and Gram-negative?

  • Chemotherapeutic agent
  • Antimicrobial chemotherapy
  • Broad spectrum antibiotic (correct)
  • Narrow spectrum antibiotic

Which class of antibiotics includes agents that inhibit cell wall synthesis?

  • Penicillins
  • Drug Target Sites
  • β-Lactams (correct)
  • Antibiotic Attributes of an Ideal Antimicrobial Agent

What are the general properties of ideal antimicrobial agents?

  • Highly effective against a broad spectrum of pathogens, low toxicity, and minimal side effects (correct)
  • Effective against both bacteria and viruses, high toxicity, and minimal side effects
  • Only effective against Gram-positive bacteria, low toxicity, and minimal side effects
  • Effective against specific pathogens, high toxicity, and significant side effects

Which type of penicillin is less acid labile and can be taken orally?

<p>Penicillin-V (C)</p> Signup and view all the answers

Which salt of benzylpenicillin is used for prolonged action via intramuscular administration?

<p>Benzathine salt of benzylpenicillin (B)</p> Signup and view all the answers

Why is benzylpenicillin effective against a narrow spectrum of bacteria?

<p>It is unable to penetrate the cell wall of Gram-negative bacteria (C)</p> Signup and view all the answers

Flashcards

Broad-spectrum antibiotic

Affects a wide range of bacteria, including both Gram-positive and Gram-negative.

Beta-Lactams

A class of antibiotics that inhibits cell wall synthesis in bacteria.

Ideal antimicrobial agent properties

Highly effective against pathogens, low toxicity, minimal side effects.

Penicillin-V

Less acid-labile, making it suitable for oral administration.

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Benzathine benzylpenicillin

Used for prolonged action via intramuscular injection.

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Benzylpenicillin's narrow spectrum

Cannot penetrate the cell wall of Gram-negative bacteria.

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Study Notes

Types of Antibiotics

  • Broad-spectrum antibiotics target a wide range of bacteria, including both Gram-positive and Gram-negative types.

Antibiotic Classes

  • Beta-lactam antibiotics include agents that inhibit cell wall synthesis, crucial for bacterial structural integrity.

Ideal Antimicrobial Properties

  • Ideally, antimicrobial agents should have a selective toxicity, minimal side effects on host, effective against pathogens, stability in body fluids, and an ability to penetrate tissues.

Penicillin Types

  • Penicillin V is less acid labile, allowing for oral administration without significant degradation.

Benzylpenicillin Administration

  • Benzylpenicillin procaine salt is used for prolonged action through intramuscular administration, enhancing the antibiotic’s duration in the system.

Spectrum of Benzylpenicillin

  • Benzylpenicillin is effective against a narrow spectrum of bacteria due to its specific mechanism targeting mainly Gram-positive organisms and a select few Gram-negative bacteria.

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