Antihypertensive Agents Quiz

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Questions and Answers

Which type of medication is recommended by NICE in the UK for individuals under 55 years old with high blood pressure?

  • Angiotensin II receptor antagonists
  • Calcium channel blockers
  • Thiazide diuretics
  • ACE inhibitors (correct)

Why are thiazide diuretics not prescribed as often as some newer drugs?

  • They are more expensive compared to newer drugs
  • Due to being less effective than newer drugs
  • Because they are associated with increased risk of new-onset diabetes (correct)
  • Because they have more side effects than newer drugs

What is the mechanism of action of calcium channel blockers?

  • Preventing the conversion of angiotensin I into angiotensin II
  • Blocking the entry of calcium into muscle cells in artery walls (correct)
  • Blocking the entry of sodium into muscle cells
  • Inhibition of angiotensin-converting enzyme (ACE)

Why are potassium-sparing diuretics like amiloride and triamterene seldom prescribed as monotherapy?

<p>Stronger public evidence is needed for their blood pressure reducing effect (C)</p> Signup and view all the answers

What enzyme do ACE inhibitors inhibit?

<p>Angiotensin-converting enzyme (ACE) (B)</p> Signup and view all the answers

What is the primary goal of antihypertensive therapy?

<p>To prevent complications of high blood pressure (C)</p> Signup and view all the answers

How much can a reduction of blood pressure by 5 mmHg decrease the risk of stroke according to evidence?

<p>34% (A)</p> Signup and view all the answers

Which class of antihypertensives is among the most important and widely used medications?

<p>ACE inhibitors (D)</p> Signup and view all the answers

What plays a part in determining the dosage and type of medication administered for hypertension?

<p>Patient's associated clinical conditions and end-organ damage (D)</p> Signup and view all the answers

Why is it important to consider the side effect profiles, ability to prevent endpoints, and cost of different classes of antihypertensive drugs?

<p>To minimize the negative impacts on national healthcare budgets (D)</p> Signup and view all the answers

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