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Antihypertensive Agents Quiz

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Questions and Answers

Which type of medication is recommended by NICE in the UK for individuals under 55 years old with high blood pressure?

Angiotensin II receptor antagonists

Calcium channel blockers

Thiazide diuretics

ACE inhibitors (correct)

Why are thiazide diuretics not prescribed as often as some newer drugs?

They are more expensive compared to newer drugs

Due to being less effective than newer drugs

Because they are associated with increased risk of new-onset diabetes (correct)

Because they have more side effects than newer drugs

What is the mechanism of action of calcium channel blockers?

Preventing the conversion of angiotensin I into angiotensin II

Blocking the entry of calcium into muscle cells in artery walls (correct)

Blocking the entry of sodium into muscle cells

Inhibition of angiotensin-converting enzyme (ACE)

Why are potassium-sparing diuretics like amiloride and triamterene seldom prescribed as monotherapy?

Stronger public evidence is needed for their blood pressure reducing effect Signup and view all the answers

What enzyme do ACE inhibitors inhibit?

Angiotensin-converting enzyme (ACE) Signup and view all the answers

What is the primary goal of antihypertensive therapy?

To prevent complications of high blood pressure Signup and view all the answers

How much can a reduction of blood pressure by 5 mmHg decrease the risk of stroke according to evidence?

34% Signup and view all the answers

Which class of antihypertensives is among the most important and widely used medications?

ACE inhibitors Signup and view all the answers

What plays a part in determining the dosage and type of medication administered for hypertension?

Patient's associated clinical conditions and end-organ damage Signup and view all the answers

Why is it important to consider the side effect profiles, ability to prevent endpoints, and cost of different classes of antihypertensive drugs?

To minimize the negative impacts on national healthcare budgets Signup and view all the answers