Antigen Presentation Pathway in B Cells

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Questions and Answers

What is the primary function of antibodies produced during the humoral immune response?

  • To activate complement proteins
  • To bind to and neutralize extracellular pathogens (correct)
  • To directly kill pathogens
  • To stimulate the proliferation of T helper cells

Which type of antigen requires the direct involvement of T helper cells for effective antibody production by B cells?

  • Thymus-independent antigens
  • Thymus-dependent antigens (correct)
  • Non-protein antigens
  • Self-antigens

What is the primary role of cytokines secreted by T helper cells during the humoral immune response?

  • To stimulate the proliferation and differentiation of B cells (correct)
  • To activate complement proteins
  • To inhibit the production of antibodies
  • To directly kill pathogens

Which immunoglobulin class is typically associated with the initial antibody response to a foreign antigen?

<p>IgM (C)</p> Signup and view all the answers

What is the primary mechanism by which B cells differentiate into antibody-producing plasma cells during the humoral immune response?

<p>Cytokine-induced differentiation (D)</p> Signup and view all the answers

Which of the following is a key characteristic of the long-term memory response in the humoral immune system?

<p>Rapid production of high-affinity antibodies (B)</p> Signup and view all the answers

What is the main role of the B7 molecules in the activation of TH cells?

<p>To provide a co-stimulatory signal for proper antigen presentation and TH cell activation (C)</p> Signup and view all the answers

What is the primary function of the CD40L molecule expressed on activated TH cells?

<p>To induce B cell proliferation and antibody production (D)</p> Signup and view all the answers

Which of the following cytokines secreted by TH cells is MOST important for inducing immunoglobulin class switching in B cells?

<p>IL-4 (D)</p> Signup and view all the answers

What is the primary function of B cell memory cells generated during the primary immune response?

<p>To rapidly proliferate and secrete antibodies upon re-exposure to the same antigen (A)</p> Signup and view all the answers

What is the key difference between T cell-dependent (TD) and T cell-independent (TI) antigens in terms of B cell activation?

<p>TD antigens require the help of TH cells for B cell activation, while TI antigens do not (D)</p> Signup and view all the answers

Which of the following is the MOST important step in the process of B cell activation and antibody production?

<p>Direct contact between B cells and activated TH cells (B)</p> Signup and view all the answers

What is the main function of B cell activation in the acquired immune response?

<p>Produce antibodies to fight off pathogens (C)</p> Signup and view all the answers

Which type of immune response involves antibody production by B lymphocytes?

<p>Humoral immunity (D)</p> Signup and view all the answers

How do T helper (TH) cells contribute to the immune response?

<p>Release cytokines to activate other immune cells (D)</p> Signup and view all the answers

What process involves B cells switching the class of immunoglobulins they produce?

<p>Immunoglobulin class switching (D)</p> Signup and view all the answers

Which action is NOT typically associated with cytokine secretion in the immune system?

<p>Directly killing infected cells (C)</p> Signup and view all the answers

During B cell activation, what is the primary role of antibodies produced by plasma cells?

<p>Recognize and bind to specific antigens (D)</p> Signup and view all the answers

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