Antigen Presentation and Helper T Cell Activation
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Questions and Answers

What is the role of MHC class I molecules in the body?

  • Facilitate antigen presentation to dendritic cells
  • Facilitate antigen presentation to basophils
  • Facilitate antigen presentation to B cells
  • Facilitate antigen presentation to T cells (correct)

Which part of the MHC class I molecules anchors them in the cell membrane?

  • α1 domain
  • C‐terminus
  • Hydrophobic section (correct)
  • β2‐microglobulin

Which domains of MHC class I molecules form a groove bounded by two α‐helices and a β‐pleated sheet floor?

  • α1 and β1 (correct)
  • α1 and α2
  • α3 and β2‐microglobulin
  • α2 and β2

Which part of the MHC class I molecule resembles classic Ig domains in its folding pattern?

<p>α3 region (D)</p> Signup and view all the answers

Which type of cells can perform cross-presentation of extracellular antigens on MHC class I molecules?

<p>Dendritic cells (A)</p> Signup and view all the answers

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