5 Questions
What is the role of MHC class I molecules in the body?
Facilitate antigen presentation to T cells
Which part of the MHC class I molecules anchors them in the cell membrane?
Hydrophobic section
Which domains of MHC class I molecules form a groove bounded by two α‐helices and a β‐pleated sheet floor?
α1 and β1
Which part of the MHC class I molecule resembles classic Ig domains in its folding pattern?
α3 region
Which type of cells can perform cross-presentation of extracellular antigens on MHC class I molecules?
Dendritic cells
Learn about the process of antigen presentation by antigen-presenting cells and the activation of helper T cells. Understand the role of class II MHC molecules, cytokines, and costimulatory reactions in the immune response.
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