Tricyclic Antidepressants (TCAs)
8 Questions
3 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What neurotransmitters do tricyclic antidepressants inhibit the reuptake of?

Serotonin and norepinephrine

The term 'tricyclic' in tricyclic antidepressants refers to two rings.

False (B)

Which of the following is a tricyclic antidepressant?

  • Amitriptyline
  • Nortriptyline
  • Desipramine
  • All of the above (correct)

Which of the following are indications for tricyclic antidepressants?

<p>All of the above (D)</p> Signup and view all the answers

Which of the following is a contraindication for tricyclic antidepressants?

<p>All of the above (D)</p> Signup and view all the answers

Which of the following is a possible adverse effect of tricyclic antidepressants?

<p>All of the above (D)</p> Signup and view all the answers

Tricyclic antidepressants should not be taken with:

<p>Both A and B (C)</p> Signup and view all the answers

Tricyclic antidepressants are typically considered first-line treatments.

<p>False (B)</p> Signup and view all the answers

Flashcards

Tricyclic Antidepressants (TCAs)

Medications that inhibit the reuptake of serotonin and norepinephrine.

Examples of TCA drugs

Amitriptyline, Nortriptyline, Desipramine, Trimipramine.

Indications for TCAs

Depression, pain, neuropathy, fibromyalgia, anxiety disorders.

Common side effects of TCAs

Blurred vision, dizziness, drowsiness, GI upset, insomnia, cardiovascular issues, sexual dysfunction, seizures.

Signup and view all the flashcards

Contraindications for TCAs

Recent MI, myelography, concurrent use of other antidepressants, pregnancy, lactation, suicidal ideation.

Signup and view all the flashcards

Drugs with interactions with TCAs

Other antidepressants and anticoagulants.

Signup and view all the flashcards

Reuptake

The process of neurotransmitters being reabsorbed back into the presynaptic neuron.

Signup and view all the flashcards

TCAs as First-Line Treatment

TCAs have many side effects and newer medications are preferred.

Signup and view all the flashcards

Arrhythmias (TCA Side Effect)

Irregular heartbeats that can be a side effect of TCAs.

Signup and view all the flashcards

Orthostatic Hypotension (TCA)

A sudden drop in blood pressure when standing up; a TCA side effect.

Signup and view all the flashcards

Study Notes

  • Tricyclic Antidepressants (TCAs) impact two hormones.
  • TCAs inhibit the reuptake of serotonin and norepinephrine.
  • Tricyclic refers to the three rings in the drug's chemical structure.
  • Reuptake means reabsorb.
  • TCAs are not first-line treatments due to many side effects.

Indications for TCAs

  • Depression
  • Pain
  • Neuropathy
  • Fibromyalgia
  • Anxiety disorders

Contraindications for TCAs

  • Recent myocardial infarction (MI)
  • Myelography
  • Concurrent use of other antidepressant medications
  • Pregnancy
  • Lactation
  • Suicidal ideation

Adverse Effects of TCAs

  • Blurry vision
  • Dizziness
  • Drowsiness
  • GI upset
  • Insomnia
  • Cardiovascular issues: arrhythmias, tachycardia, orthostatic hypotension, sexual dysfunction
  • Seizures

Drug-Drug Interactions

  • Other antidepressants
  • Anticoagulants
  • Examples of TCAs
    • Amitriptyline
    • Nortriptyline
    • Desipramine
    • Trimipramine

Studying That Suits You

Use AI to generate personalized quizzes and flashcards to suit your learning preferences.

Quiz Team

Description

Explore Tricyclic Antidepressants (TCAs), which inhibit serotonin and norepinephrine reuptake. These drugs, characterized by their three-ring structure, treat depression, pain, and anxiety. Learn about contraindications, including recent myocardial infarction and pregnancy, and potential side effects like blurry vision and cardiovascular issues.

More Like This

Use Quizgecko on...
Browser
Open
Browser
Browser