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Questions and Answers
What is a major side effect associated with tetracycline use?
What is a major side effect associated with tetracycline use?
- Nephrotoxicity
- Respiratory distress
- Photosensitivity (correct)
- Cardiovascular complications
Which condition is NOT indicated for treatment with tetracycline?
Which condition is NOT indicated for treatment with tetracycline?
- Syphilis
- Brucellosis
- Methicillin-resistant S. Aureus
- Ocular infections (correct)
Why should tetracycline be avoided during pregnancy?
Why should tetracycline be avoided during pregnancy?
- It is known to cause respiratory issues in infants.
- It is associated with cardiovascular defects.
- It has teratogenic effects and can stain children's teeth. (correct)
- It induces hyperactivity in newborns.
What is a significant drug-drug interaction concern with tetracycline?
What is a significant drug-drug interaction concern with tetracycline?
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What is a potential consequence of continuous use of chloramphenicol eye drops?
What is a potential consequence of continuous use of chloramphenicol eye drops?
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Study Notes
Tetracycline
- Broad-spectrum antibiotic
- Naturally occurring antimicrobial agent
- Used to treat Brucellosis, travelers diarrhea, Syphilis, and Methicillin resistant S.Aureus
- Investigations ongoing to determine other potential uses for the drug
- Binds to the 30S ribosome, inhibiting protein synthesis
- Administered orally
- Absorbed in the stomach and found in joints, ascitic fluid, and pleural fluid
- Can cause nausea and vomiting
- Can cause photosensitivity, leading to sunburns
- Blocking shots are given before sun exposure to prevent photosensitivity
Chloramphenicol
- Highly associated with bone marrow toxicity
- Found in Gille drops and certain eye drops
- Primarily used for eye infections
- Continuous use of eye drops can lead to bone marrow suppression
Drug-Drug Interaction
- Avoid milk ingestion with tetracycline
- Breastfeeding mothers can take tetracycline because calcium in milk will chelate the antibiotic
Tetracycline
- Teratogenic, meaning it can cause birth defects
- Should not be given to pregnant women
- Can stain the teeth of children born to mothers who took tetracycline
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Description
Explore the characteristics and uses of tetracycline and chloramphenicol in this quiz. Learn about their mechanisms, side effects, and drug interactions. Test your knowledge on these important antibiotics used in treating various infections.
