40 Questions
What is the cardinal rule when using antibiotics?
Use the correct dosing schedule
Why is a loading dose recommended for antibiotics?
To achieve therapeutic blood levels quickly
What is the role of antibiotic therapy in periodontal disease?
To eliminate bacteria associated with the disease
What is the mechanism of action of tetracyclines in periodontal therapy?
Inhibit cell wall synthesis
Which antibiotic is known for its broad spectrum of activity and bacteriostatic properties in periodontal therapy?
Tetracycline
What are the common pathogens associated with gingivitis?
Fuso, strep, & actinomycetes
What is the definition of an antibiotic?
A substance that kills or inhibits the growth of microorganisms
What is the term for an antimicrobial that acts on a limited number of microbial species?
Narrow Spectrum Antimicrobial
Which term refers to a substance that kills or destroys microorganisms by inhibiting their growth?
Microcidal
What is the action of a Microstatic antimicrobial?
The organism is reversibly inhibited at specific metabolic processes
Which term refers to an antimicrobial that acts on a wide range of species?
Broad Spectrum Antimicrobial
What is the definition of chemotherapy in the context of antibiotics?
A treatment of systemic infections with specific drugs
Which antibiotic is considered a choice for treating periodontal abscesses?
Metronidazole
What is the most common adverse effect of Metronidazole?
Metallic taste
Which antibiotic is contraindicated in the first trimester of pregnancy?
Tetracycline HCl
Which antibiotic is known for its potent bacteriostatic activity against strict anaerobes?
Clindamycin
Which antibiotic can induce ulcerative colitis as an adverse effect?
Clindamycin
Which antibiotic has weak activity against A.A., Eikenella, and Fusobacterium?
Erythromycin
Which systemic antibiotic regimen is considered more effective than a single agent for treating aggressive and recurrent periodontitis?
$Amoxicillin (500 mg TID) and metronidazole (250 mg TID) for 8 days$
What is the advantage of local delivery devices for antibiotics in periodontal treatment?
$Bypasses the metabolism by the liver$
Antibiotics are primarily used to promote the growth of microorganisms.
False
Chemotherapy involves the treatment of systemic infections with drugs that selectively suppress the infecting microorganism without significantly affecting the host.
True
An antimicrobial refers to both antibiotics and synthetic agents active against microbes.
True
Microcidal agents inhibit the growth of microorganisms by reversibly inhibiting specific metabolic processes.
False
Narrow Spectrum Antimicrobials act on a wide range of microbial species.
False
Broad Spectrum Antimicrobials inhibit the growth of a limited number of microbial species.
False
Tetracyclines are considered bactericidal antibiotics.
False
Metronidazole is relatively ineffective in suppressing A. actinomycetemcomitans.
True
Amoxicillin in combination with clavulonic acid is not indicated in the presence of oral bacteria capable of producing β-lactamase.
False
Doxycycline has more patient compliance than tetracycline due to its once-daily dosing.
True
Penicillin G is considered a broad-spectrum antibiotic.
False
Erythromycin is effective against Gram-negative bacteria such as Legionella and Mycoplasma.
True
Ciprofloxacin is effective in the treatment of periodontal super infections caused by enteric bacteria, pseudomonas, or staphylococci.
True
Clindamycin has weak activity against facultative pathogens like A.a. and Eikenella.
False
Erythromycin reaches effective concentrations in gingival fluid and has strong activity against A.A., Eikenella, and Fusobacterium.
False
Azithromycin is primarily bacteriostatic and has a narrow spectrum of activity.
False
Tetracycline HCl for 21 days is one of the most effective regimens for treating aggressive and recurrent periodontitis.
False
Local delivery devices for antibiotics in periodontal treatment have limitations including dose limitation due to a relatively small area.
True
Local delivery devices for antibiotics bypass the metabolism by the liver, making them a safe and convenient route of administration.
True
Systemic antibiotics rarely enhance the treatment of chronic periodontitis.
True
Test your knowledge about the use of antibiotics and local delivery devices in periodontology. Learn about the terminology and definitions related to antibiotics and their role in eliminating infections caused by pathogenic microorganisms.
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