Antibiotics and Ribosomal Units Pharmacology Quiz
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Questions and Answers

Which of the following antibiotics inhibits the 50S ribosomal subunit and prevents the transpeptidation reaction during protein synthesis?

  • Aminoglycosides
  • Tetracyclines
  • Chloramphenicol (correct)
  • Macrolides
  • Which antibiotic class binds to the 30S ribosomal subunit and causes misreading of the mRNA template?

  • Aminoglycosides (correct)
  • Chloramphenicol
  • Tetracyclines
  • Macrolides
  • Which of the following antibiotics inhibits the 70S bacterial ribosome by preventing the attachment of aminoacyl-tRNA to the acceptor site?

  • Chloramphenicol
  • Tetracyclines
  • Aminoglycosides
  • Macrolides (correct)
  • Which antibiotic class binds to the 30S ribosomal subunit and prevents the binding of aminoacyl-tRNA to the acceptor site?

    <p>Tetracyclines (C)</p> Signup and view all the answers

    Which of the following antibiotics is known to cause ototoxicity and nephrotoxicity due to its ability to bind to the 30S ribosomal subunit?

    <p>Aminoglycosides (A)</p> Signup and view all the answers

    Which antibiotic class is known to cause bone and tooth discoloration, especially in children, due to its chelation of calcium ions?

    <p>Tetracyclines (B)</p> Signup and view all the answers

    Which of the following antibiotics is known to cause aplastic anemia and gray baby syndrome in neonates due to its inability to be metabolized and excreted efficiently?

    <p>Chloramphenicol (C)</p> Signup and view all the answers

    Which antibiotic class is known to bind to the 50S ribosomal subunit and cause the dissociation of peptidyl-tRNA from the ribosome?

    <p>Macrolides (B)</p> Signup and view all the answers

    Which antibiotic class is known to inhibit protein synthesis by preventing the binding of aminoacyl-tRNA to the A site on the ribosome?

    <p>Tetracyclines (A)</p> Signup and view all the answers

    Which of the following antibiotics is known to cause gastrointestinal side effects due to its ability to disrupt the normal gut microbiome?

    <p>Macrolides (A)</p> Signup and view all the answers

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