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Questions and Answers
Where are ribosomes located in mammalian cells?
What is the process by which cells make proteins?
What is the difference between mammalian and bacterial ribosomes?
What is the first step in protein synthesis?
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What is the end product of protein synthesis?
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Where does protein synthesis occur in bacterial cells?
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What is the role of initiation in protein synthesis?
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What is the purpose of protein synthesis inhibitors?
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What is the mechanism of action of aminoglycosides?
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What is the significance of the peak/MIC ratio in aminoglycoside therapy?
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Why do aminoglycosides have minimal action against anaerobes?
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How are aminoglycosides excreted from the body?
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What is the half-life of aminoglycosides in patients with normal renal function?
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What is the mechanism of resistance to aminoglycosides?
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What is the preferred treatment for plague and tularaemia?
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What is the significance of the volume of distribution of aminoglycosides?
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What is the primary function of the small and large subunits of the ribosome during translation?
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What is the role of the stop codon during translation?
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What is the primary difference between antibiotics and antimicrobials?
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What is the key difference between bacteriostatic and bactericidal antimicrobials?
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What is the focus of pharmacokinetics?
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What is the primary characteristic of aminoglycosides?
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What is the MIC (minimum inhibitory concentration) of an antimicrobial?
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What is the relationship between gentamicin, amikacin, and tobramycin?
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What is the primary mechanism of action of tigecycline in bacterial cells?
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What is the main reason for the decreased absorption of tetracyclines in the presence of divalent and trivalent cations?
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What is the primary mechanism of resistance to tetracyclines in bacteria?
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What is the primary indication for the use of doxycycline in respiratory tract infections?
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What is the unique feature of demeclocycline compared to other tetracyclines?
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What is the primary route of excretion for tetracyclines?
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What is the primary mechanism of action of tetracyclines against Chlamydia?
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What is the primary reason for the use of tetracyclines in the treatment of acne?
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Which of the following bacteria is not susceptible to aminoglycosides?
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What is the primary mechanism of action of aminoglycosides?
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Which aminoglycoside has the widest spectrum of activity?
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What is the primary side effect of aminoglycosides on the kidney?
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What is the primary side effect of aminoglycosides on the ear?
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What is the primary indication for using tobramycin over gentamicin?
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What is the primary mechanism of action of tetracyclines?
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Which of the following is a common side effect of aminoglycosides that may go unrecognized?
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